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http://hdl.handle.net/1942/37463
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DC Field | Value | Language |
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dc.contributor.author | Omote, Kazunori | - |
dc.contributor.author | VERBRUGGE, Frederik | - |
dc.contributor.author | Borlaug, Barry A. | - |
dc.date.accessioned | 2022-06-08T09:43:13Z | - |
dc.date.available | 2022-06-08T09:43:13Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2022-05-19T08:45:42Z | - |
dc.identifier.citation | Annual Review of Medicine, 73 (1) , p. 321 -337 | - |
dc.identifier.uri | http://hdl.handle.net/1942/37463 | - |
dc.description.abstract | Approximately half of all patients with heart failure (HF) have a preserved ejection fraction, and the prevalence is growing rapidly given the aging population in many countries and the rising prevalence of obesity, diabetes, and hypertension. Functional capacity and quality of life are severely impaired in heart failure with preserved ejection fraction (HFpEF), and morbidity and mortality are high. In striking contrast to HF with reduced ejection fraction, there are few effective treatments currently identified for HFpEF, and these are limited to decongestion by diuretics, promotion of a healthy active lifestyle, and management of comorbidities. Improved phenotyping of subgroups within the overall HFpEF population might enhance individualization of treatment. This review focuses on the current understanding of the pathophysiologic mechanisms underlying HFpEF and treatment strategies for this complex syndrome. | - |
dc.description.sponsorship | National Institutes of Health [R01 HL128526]; Special Research Fund | - |
dc.language.iso | en | - |
dc.publisher | ANNUAL REVIEWS | - |
dc.rights | 2022 by Annual Reviews. All rights reserved | - |
dc.subject.other | heart failure | - |
dc.subject.other | heart failure with preserved ejection fraction | - |
dc.subject.other | pathophysiology | - |
dc.subject.other | treatment | - |
dc.subject.other | Aged | - |
dc.subject.other | Comorbidity | - |
dc.subject.other | Humans | - |
dc.subject.other | Quality of Life | - |
dc.subject.other | Stroke Volume | - |
dc.subject.other | Ventricular Function, Left | - |
dc.subject.other | Heart Failure | - |
dc.title | Heart Failure with Preserved Ejection Fraction: Mechanisms and Treatment Strategies | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 337 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 321 | - |
dc.identifier.volume | 73 | - |
local.format.pages | 17 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Borlaug, BA (corresponding author), Mayo Clin, Dept Cardiovasc Med, Rochester, MN 55905 USA. | - |
dc.description.notes | borlaug.barry@mayo.edu | - |
local.publisher.place | 4139 EL CAMINO WAY, PO BOX 10139, PALO ALTO, CA 94303-0139 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
dc.identifier.doi | 10.1146/annurev-med-042220-022745 | - |
dc.identifier.pmid | 34379445 | - |
dc.identifier.isi | WOS:000789889600021 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Omote, Kazunori; Verbrugge, Frederik H.; Borlaug, Barry A.] Mayo Clin, Dept Cardiovasc Med, Rochester, MN 55905 USA. | - |
local.description.affiliation | [Verbrugge, Frederik H.] Univ Hosp Brussels, Ctr Cardiovasc Dis, B-1090 Jette, Belgium. | - |
local.description.affiliation | [Verbrugge, Frederik H.] Hasselt Univ, Fac Med & Life Sci, Biomed Res Inst, B-3500 Hasselt, Belgium. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.contributor | Omote, Kazunori | - |
item.contributor | VERBRUGGE, Frederik | - |
item.contributor | Borlaug, Barry A. | - |
item.accessRights | Open Access | - |
item.validation | ecoom 2023 | - |
item.fullcitation | Omote, Kazunori; VERBRUGGE, Frederik & Borlaug, Barry A. (2022) Heart Failure with Preserved Ejection Fraction: Mechanisms and Treatment Strategies. In: Annual Review of Medicine, 73 (1) , p. 321 -337. | - |
crisitem.journal.issn | 0066-4219 | - |
crisitem.journal.eissn | 1545-326X | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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annurev-med-042220-022745.pdf | Published version | 686.66 kB | Adobe PDF | View/Open |
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