Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/37623
Full metadata record
DC FieldValueLanguage
dc.contributor.authorLefort, M.-
dc.contributor.authorSharmin , S.-
dc.contributor.authorAndersen, J. B.-
dc.contributor.authorVukusic, S.-
dc.contributor.authorCasey, R.-
dc.contributor.authorDebouverie, M.-
dc.contributor.authorEdan, G.-
dc.contributor.authorCiron, J.-
dc.contributor.authorRuet, A.-
dc.contributor.authorDe Seze, J.-
dc.contributor.authorMaillart, E.-
dc.contributor.authorZephir, H.-
dc.contributor.authorLabauge, P.-
dc.contributor.authorDefer, G.-
dc.contributor.authorLebrun-Frenay, C.-
dc.contributor.authorMoreau, T.-
dc.contributor.authorBerger , E.-
dc.contributor.authorClavelou, P.-
dc.contributor.authorPelletier, J.-
dc.contributor.authorStankoff, B.-
dc.contributor.authorGout, O.-
dc.contributor.authorThouvenot, E.-
dc.contributor.authorHeinzlef, O.-
dc.contributor.authorAl-Khedr, A.-
dc.contributor.authorBourre, B.-
dc.contributor.authorCasez, O.-
dc.contributor.authorCabre, P.-
dc.contributor.authorMontcuquet, A.-
dc.contributor.authorWahab, A.-
dc.contributor.authorCamdessanche, J. P.-
dc.contributor.authorMaurousset, A.-
dc.contributor.authorBen Nasr, H.-
dc.contributor.authorHankiewicz, K.-
dc.contributor.authorPottier, C.-
dc.contributor.authorMaubeuge, N.-
dc.contributor.authorNifle, C.-
dc.contributor.authorLaplaud, D. A.-
dc.contributor.authorHorakova, D.-
dc.contributor.authorDimitri-Boulos, D.-
dc.contributor.authorHavrdova, E. K.-
dc.contributor.authorAlroughani, R.-
dc.contributor.authorIzquierdo, G.-
dc.contributor.authorEichau, S.-
dc.contributor.authorOzakbas, S.-
dc.contributor.authorPatti, F.-
dc.contributor.authorOnofrj, M.-
dc.contributor.authorLugaresi, A.-
dc.contributor.authorTerzi, M.-
dc.contributor.authorGrammond, P.-
dc.contributor.authorGrand'Maison, F.-
dc.contributor.authorYamout, B.-
dc.contributor.authorPrat, A.-
dc.contributor.authorGirard, M.-
dc.contributor.authorDuquette, P.-
dc.contributor.authorBoz, C.-
dc.contributor.authorTrojano, M.-
dc.contributor.authorMcCombe, P.-
dc.contributor.authorSlee, M.-
dc.contributor.authorLechner-Scott, J.-
dc.contributor.authorTurkoglu, R.-
dc.contributor.authorSola, P.-
dc.contributor.authorFerraro, D.-
dc.contributor.authorGranella, F.-
dc.contributor.authorShaygannejad, V-
dc.contributor.authorPrevost, J.-
dc.contributor.authorMaimone, D.-
dc.contributor.authorSkibina, O.-
dc.contributor.authorBuzzard, K.-
dc.contributor.authorVan der Walt, A.-
dc.contributor.authorKarabudak, R.-
dc.contributor.authorVAN WIJMEERSCH, Bart-
dc.contributor.authorCsepany, T.-
dc.contributor.authorSpitaleri, D.-
dc.contributor.authorVucic, S.-
dc.contributor.authorKoch-Henriksen, N.-
dc.contributor.authorSellebjerg, F.-
dc.contributor.authorSoerensen , P. S.-
dc.contributor.authorChristensen, C. C. Hilt-
dc.contributor.authorRasmussen, P., V-
dc.contributor.authorJensen, M. B.-
dc.contributor.authorFrederiksen, J. L.-
dc.contributor.authorBramow, S.-
dc.contributor.authorMathiesen, H. K.-
dc.contributor.authorSchreiber, K., I-
dc.contributor.authorButzkueven, H.-
dc.contributor.authorMagyari, M.-
dc.contributor.authorKalincik, T.-
dc.contributor.authorLeray, E.-
dc.date.accessioned2022-06-30T13:43:46Z-
dc.date.available2022-06-30T13:43:46Z-
dc.date.issued2022-
dc.date.submitted2022-06-21T11:18:44Z-
dc.identifier.citationBMC Medical research methodology (Online), 22 (1) (Art N° 155)-
dc.identifier.urihttp://hdl.handle.net/1942/37623-
dc.description.abstractBackground Natalizumab and fingolimod are used as high-efficacy treatments in relapsing-remitting multiple sclerosis. Several observational studies comparing these two drugs have shown variable results, using different methods to control treatment indication bias and manage censoring. The objective of this empirical study was to elucidate the impact of methods of causal inference on the results of comparative effectiveness studies. Methods Data from three observational multiple sclerosis registries (MSBase, the Danish MS Registry and French OFSEP registry) were combined. Four clinical outcomes were studied. Propensity scores were used to match or weigh the compared groups, allowing for estimating average treatment effect for treated or average treatment effect for the entire population. Analyses were conducted both in intention-to-treat and per-protocol frameworks. The impact of the positivity assumption was also assessed. Results Overall, 5,148 relapsing-remitting multiple sclerosis patients were included. In this well-powered sample, the 95% confidence intervals of the estimates overlapped widely. Propensity scores weighting and propensity scores matching procedures led to consistent results. Some differences were observed between average treatment effect for the entire population and average treatment effect for treated estimates. Intention-to-treat analyses were more conservative than per-protocol analyses. The most pronounced irregularities in outcomes and propensity scores were introduced by violation of the positivity assumption. Conclusions This applied study elucidates the influence of methodological decisions on the results of comparative effectiveness studies of treatments for multiple sclerosis. According to our results, there are no material differences between conclusions obtained with propensity scores matching or propensity scores weighting given that a study is sufficiently powered, models are correctly specified and positivity assumption is fulfilled.-
dc.description.sponsorshipOFSEP was supported by a grant provided by the French State and handled by the "Agence Nationale de la Recherche", within the framework of the "Investments for the Future" program, under the reference ANR10-COHO-002, by the Eugène Devic EDMUS Foundation against multiple sclerosis and by the ARSEP Foundation. ML has recieved travel grant from ARSEP foundation for this project. The Clinical Outcomes Research unit at the University of Melbourne received funding from NHMRC (grant number-
dc.language.isoen-
dc.publisherBMC-
dc.rightsThe Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. 1140766, 1129789, and 1157717) to support this study. The MSBase Foundation is a not-for-profit organization that receives support from Biogen, Novartis, Merck, Roche, Teva Pharmaeutical Industries and Sanofi Genzyme. The Danish Multiple Sclerosis Registry did not receive any fund‑ ing to collaborate in this study-
dc.subject.otherEffectiveness-
dc.subject.otherMultiple sclerosis-
dc.subject.otherPropensity score-
dc.subject.otherIndication bias-
dc.subject.otherCausal contrasts-
dc.subject.otherCensoring-
dc.subject.otherPositivity assumption-
dc.titleImpact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis-
dc.typeJournal Contribution-
dc.identifier.issue1-
dc.identifier.volume22-
local.bibliographicCitation.jcatA1-
dc.description.notesLeray, E (corresponding author), Univ Rennes, Arenes UMR 6051, RSMS Rech Serv & Management Sante U1309, EHESP,CNRS,Inserm, Rennes, France.; Leray, E (corresponding author), Univ Rennes, CIC 1414 Ctr D, CHU Rennes, Invest Clin Rennes,Inserm, F-35000 Rennes, France.; Kalincik, T (corresponding author), Univ Melbourne, Dept Med, Melbourne, Vic, Australia.-
dc.description.notestomas.kalincik@unimelb.edu.au; emmanuelle.leray@ehesp.fr-
local.publisher.placeCAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND-
local.type.refereedRefereed-
local.type.specifiedArticle-
local.bibliographicCitation.artnr155-
dc.identifier.doi10.1186/s12874-022-01623-8-
dc.identifier.pmid35637426-
dc.identifier.isiWOS:000805581400002-
dc.contributor.orcidBramow, Stephan/0000-0001-9482-1771; Sellebjerg,-
dc.contributor.orcidFinn/0000-0002-1333-9623-
local.provider.typewosris-
local.description.affiliation[Lefort, M.; Leray, E.] Univ Rennes, Arenes UMR 6051, RSMS Rech Serv & Management Sante U1309, EHESP,CNRS,Inserm, Rennes, France.-
local.description.affiliation[Lefort, M.; Leray, E.] Univ Rennes, CIC 1414 Ctr D, CHU Rennes, Invest Clin Rennes,Inserm, F-35000 Rennes, France.-
local.description.affiliation[Sharmin, S.; Kalincik, T.] Univ Melbourne, Dept Med, Melbourne, Vic, Australia.-
local.description.affiliation[Sharmin, S.; Magyari, M.] Royal Melbourne Hosp, Melbourne MS Ctr, Dept Neurol, Melbourne, Vic, Australia.-
local.description.affiliation[Andersen, J. B.] Copenhagen Univ Hosp, Rigshosp Glostrup, Dept Neurol, Danish Multiple Sclerosis Registry, Copenhagen, Denmark.-
local.description.affiliation[Vukusic, S.; Casey, R.] Hosp Civils Lyon, Serv Neurol, Sclerose Plaques Pathol Myeline & Neuroinflammat, Hop Neurol Pierre Wertheimer, F-69677 Lyon, France.-
local.description.affiliation[Vukusic, S.; Casey, R.] Ctr Neurosci Lyon, UMR5292, Observ Francais Sclerose Plaques, INSERM 1028, F-69003 Lyon, France.-
local.description.affiliation[Vukusic, S.; Casey, R.] CNRS, F-69003 Lyon, France.-
local.description.affiliation[Vukusic, S.; Casey, R.] Univ Claude Bernard Lyon 1, Fac Med Lyon Est, F-69000 Lyon, France.-
local.description.affiliation[Casey, R.] Eugene Devic EDMUS Fdn, F-69677 Lyon, France.-
local.description.affiliation[Debouverie, M.] Ctr Hosp Reg Univ Nancy, Serv Neurol, Hop Cent, Nancy, France.-
local.description.affiliation[Edan, G.] Ctr Hosp Univ Rennes, Serv Neurol, Hop Pontchaillou, Rennes, France.-
local.description.affiliation[Ciron, J.] Ctr Hosp Univ Toulouse, Dept Neurol, CRC SEP, Hop Purpan, Toulouse, France.-
local.description.affiliation[Ruet, A.] Ctr Hosp Univ Bordeaux, Serv Neurol, Hop Pellegrin, Bordeaux, France.-
local.description.affiliation[De Seze, J.] Hop Univ Strasbourg, Serv Malad Inflammatoires Syst Nerveux Neurol, Ctr Invest Clin Strasbourg, Hop Hautepierre,INSERM 1434, Strasbourg, France.-
local.description.affiliation[Maillart, E.] Hop La Pitie Salpetriere, Assistance Publ Hop Paris, Serv Neurol, Paris, France.-
local.description.affiliation[Zephir, H.] Ctr Hosp Univ Lille, Serv Neurol D, Hop Salengro, Lille, France.-
local.description.affiliation[Labauge, P.] Ctr Hosp Univ Montpellier, Serv Neurol, Hop Gui de Chauliac, Montpellier, France.-
local.description.affiliation[Defer, G.] Ctr Hosp Univ Caen Normandie, Serv Neurol, Hop Cote Nacre, Caen, France.-
local.description.affiliation[Lebrun-Frenay, C.] Univ Nice Cote Azur, Ctr Hosp Univ Nice, Serv Neurol, UR2CA URRIS,Hop Pasteur 2, Nice, France.-
local.description.affiliation[Moreau, T.] Ctr Hosp Univ Dijon Bourgogne, Serv Neurol, Hop Francois Mitterrand, Malad Inflammatoires Syst Nerveux & Neurol Gen, Dijon, France.-
local.description.affiliation[Berger, E.] Ctr Hosp Reg Univ Besancon, Serv Neurol, Hop Jean Minjoz, Besancon, France.-
local.description.affiliation[Clavelou, P.] Ctr Hosp Univ Clermont Ferrand, Serv Neurol, Hop Gabriel Montepied, Clermont Ferrand, France.-
local.description.affiliation[Pelletier, J.] Aix Marseille Univ, Hop La Timone, AP HM, Serv Neurol,Pole Neurosci Clin, F-13005 Marseille, France.-
local.description.affiliation[Stankoff, B.] Hop St Antoine, Assistance Publ Hop Paris, Serv Neurol, Paris, France.-
local.description.affiliation[Gout, O.] Fdn Adolphe de Rothschild Loeil & Cerveau, Serv Neurol, Paris, France.-
local.description.affiliation[Thouvenot, E.] Ctr Hosp Univ Nimes, Serv Neurol, Hop Caremeau, Nimes, France.-
local.description.affiliation[Heinzlef, O.] Ctr Hosp Intercommunal Poissy St Germain En Laye, Serv Neurol, Poissy, France.-
local.description.affiliation[Al-Khedr, A.] Ctr Hosp Univ Amiens Picardie, Serv Neurol, Site Sud, Amiens, France.-
local.description.affiliation[Bourre, B.] Rouen Univ Hosp, F-76000 Rouen, France.-
local.description.affiliation[Casez, O.] Ctr Hosp Univ Grenoble Alpes, Serv Neurol, Site Nord, Grenoble, France.-
local.description.affiliation[Cabre, P.] Ctr Hosp Univ Martinique, Serv Neurol, Hop Pierre Zobda Quitman, Fort De France, Martinique, France.-
local.description.affiliation[Montcuquet, A.] Ctr Hosp Univ Limoges, Serv Neurol, Hop Dupuytren, Limoges, France.-
local.description.affiliation[Wahab, A.] Hop Henri Mondor, Assistance Publ Hop Paris, Serv Neurol, Creteil, France.-
local.description.affiliation[Camdessanche, J. P.] Ctr Hosp Univ St Etienne, Hop Nord, Serv Neurol, St Etienne, France.-
local.description.affiliation[Maurousset, A.] Ctr Hosp Reg Univ Tours, Serv Neurol, Hop Bretonneau, Tours, France.-
local.description.affiliation[Ben Nasr, H.] Ctr Hosp Sud Francilien, Serv Neurol, Corbeil Essonnes, France.-
local.description.affiliation[Hankiewicz, K.] Hop Casanova, Ctr Hosp St Denis, Serv Neurol, St Denis, France.-
local.description.affiliation[Pottier, C.] Ctr Hosp Pontoise, Serv Neurol, Pontoise, France.-
local.description.affiliation[Maubeuge, N.] Ctr Hosp Univ Poitiers, Serv Neurol, Site Miletrie, Poitiers, France.-
local.description.affiliation[Dimitri-Boulos, D.] Hop Bicetre, Assistance Publ Hop Paris, Serv Neurol, Le Kremlin Bicetre, France.-
local.description.affiliation[Nifle, C.] Ctr Hosp Versailles, Serv Neurol, Hop Andre Mignot, Le Chesnay, France.-
local.description.affiliation[Laplaud, D. A.] CHU Nantes, Serv Neurol, F-44093 Nantes, France.-
local.description.affiliation[Laplaud, D. A.] CHU Nantes, CIC015 INSERM, F-44093 Nantes, France.-
local.description.affiliation[Laplaud, D. A.] INSERM CR1064, F-44000 Nantes, France.-
local.description.affiliation[Horakova, D.; Havrdova, E. K.] Charles Univ Prague, Fac Med 1, Dept Neurol, Prague, Czech Republic.-
local.description.affiliation[Horakova, D.; Havrdova, E. K.] Charles Univ Prague, Fac Med 1, Ctr Clin Neurosci, Prague, Czech Republic.-
local.description.affiliation[Horakova, D.; Havrdova, E. K.] Gen Univ Hosp, Prague, Czech Republic.-
local.description.affiliation[Alroughani, R.] Amiri Hosp, Dept Med, Div Neurol, Sharq, Kuwait.-
local.description.affiliation[Izquierdo, G.; Eichau, S.] Hosp Univ Virgen Macarena, Seville, Spain.-
local.description.affiliation[Ozakbas, S.] Dokuz Eylul Univ, Konak Izmir, Turkey.-
local.description.affiliation[Patti, F.] Univ Catania, GF Ingrassia Dept, Catania, Italy.-
local.description.affiliation[Patti, F.] Policlin G Rodolico, Catania, Italy.-
local.description.affiliation[Onofrj, M.] Univ G dAnnunzio, Dept Neurosci Imaging & Clin Sci, Chieti, Italy.-
local.description.affiliation[Lugaresi, A.] Univ Bologna, Dipartimento Sci Biomed & Neuromotorie, Bologna, Italy.-
local.description.affiliation[Lugaresi, A.] IRCCS Ist Sci Neurol Bologna, Bologna, Italy.-
local.description.affiliation[Terzi, M.] 19 Mayis Univ, Med Fac, Samsun, Turkey.-
local.description.affiliation[Grammond, P.] CISSS Chaudiere Appalache, Levis, PQ, Canada.-
local.description.affiliation[Grand'Maison, F.] Neuro Rive Sud, Longueuil, PQ, Canada.-
local.description.affiliation[Yamout, B.] Amer Univ Beirut, Nehme & Therese Tohme Multiple Sclerosis Ctr, Med Ctr, Beirut, Lebanon.-
local.description.affiliation[Prat, A.; Girard, M.; Duquette, P.] Hop Notre Dame De Bon Secours, Montreal, PQ, Canada.-
local.description.affiliation[Prat, A.; Girard, M.; Duquette, P.] CHUM, Montreal, PQ, Canada.-
local.description.affiliation[Prat, A.; Girard, M.; Duquette, P.] Univ Montreal, Montreal, PQ, Canada.-
local.description.affiliation[Boz, C.] Farabi Hosp, KTU Med Fac, Trabzon, Turkey.-
local.description.affiliation[Trojano, M.] Univ Bari, Dept Basic Med Sci Neurosci & Sense Organs, Bari, Italy.-
local.description.affiliation[McCombe, P.] Univ Queensland, Brisbane, Qld, Australia.-
local.description.affiliation[McCombe, P.] Royal Brisbane & Womens Hosp, Herston, Qld, Australia.-
local.description.affiliation[Slee, M.] Flinders Univ S Australia, Adelaide, SA, Australia.-
local.description.affiliation[Lechner-Scott, J.] Univ Newcastle, Sch Med & Publ Hlth, Newcastle, NSW, Australia.-
local.description.affiliation[Lechner-Scott, J.] John Hunter Hosp, Dept Neurol, Hunter New England Hlth, Newcastle, NSW, Australia.-
local.description.affiliation[Turkoglu, R.] Haydarpasa Numune Training & Res Hosp, Istanbul, Turkey.-
local.description.affiliation[Sola, P.; Ferraro, D.] Azienda Osped Univ, Dept Neurosci, Modena, Italy.-
local.description.affiliation[Granella, F.] Univ Parma, Dept Med & Surg, Parma, Italy.-
local.description.affiliation[Granella, F.] Parma Univ Hosp, Dept Emergency & Gen Med, Parma, Italy.-
local.description.affiliation[Shaygannejad, V] Isfahan Univ Med Sci, Esfahan, Iran.-
local.description.affiliation[Prevost, J.] CSSS St Jerome, St Jerome, PQ, Canada.-
local.description.affiliation[Maimone, D.] Garibaldi Hosp, Catania, Italy.-
local.description.affiliation[Skibina, O.; Buzzard, K.; Van der Walt, A.] Monash Univ, Melbourne, Vic, Australia.-
local.description.affiliation[Karabudak, R.] Hacettepe Univ, Ankara, Turkey.-
local.description.affiliation[Van Wijmeersch, B.] Rehabil & MS Ctr Overpelt, Hasselt, Belgium.-
local.description.affiliation[Van Wijmeersch, B.] Hasselt Univ, Hasselt, Belgium.-
local.description.affiliation[Csepany, T.] Univ Debrecen, Fac Med, Dept Neurol, Debrecen, Hungary.-
local.description.affiliation[Spitaleri, D.] Azienda Osped Rilievo Nazl San Giuseppe Moscati A, Avellino, Italy.-
local.description.affiliation[Vucic, S.] Westmead Hosp, Sydney, NSW, Australia.-
local.description.affiliation[Koch-Henriksen, N.] Aarhus Univ Hosp Aarhus, Dept Clin Epidemiol, Aarhus, Denmark.-
local.description.affiliation[Sellebjerg, F.; Soerensen, P. S.; Bramow, S.; Schreiber, K., I; Magyari, M.] Copenhagen Univ Hosp, Rigshosp Glostrup, Danish Multiple Sclerosis Ctr, Dept Neurol, DK-2600 Glostrup, Denmark.-
local.description.affiliation[Christensen, C. C. Hilt] Aalborg Univ Hosp, Dept Neurol, Multiple Sclerosis Unit, Aalborg, Denmark.-
local.description.affiliation[Rasmussen, P., V] Aarhus Univ Hosp, Neurol, PJJ Blvd, DK-8200 Aarhus N, Denmark.-
local.description.affiliation[Jensen, M. B.] Univ Hosp Northern Sealand, Dept Neurol, Copenhagen, Denmark.-
local.description.affiliation[Frederiksen, J. L.] Univ Copenhagen, Dept Clin Med, Copenhagen, Denmark.-
local.description.affiliation[Mathiesen, H. K.] Copenhagen Univ Hosp Herlev, Dept Neurol, Copenhagen, Denmark.-
local.description.affiliation[Butzkueven, H.] Monash Univ, Cent Clin Sch, Melbourne, Vic, Australia.-
local.description.affiliation[Butzkueven, H.] Alfred Hosp, Dept Neurol, Melbourne, Vic, Australia.-
local.description.affiliation[Butzkueven, H.] Monash Univ, Dept Neurol, Box Hill Hosp, Melbourne, Vic, Australia.-
local.uhasselt.internationalyes-
item.validationecoom 2023-
item.contributorLefort, M.-
item.contributorSharmin , S.-
item.contributorAndersen, J. B.-
item.contributorVukusic, S.-
item.contributorCasey, R.-
item.contributorDebouverie, M.-
item.contributorEdan, G.-
item.contributorCiron, J.-
item.contributorRuet, A.-
item.contributorDe Seze, J.-
item.contributorMaillart, E.-
item.contributorZephir, H.-
item.contributorLabauge, P.-
item.contributorDefer, G.-
item.contributorLebrun-Frenay, C.-
item.contributorMoreau, T.-
item.contributorBerger , E.-
item.contributorClavelou, P.-
item.contributorPelletier, J.-
item.contributorStankoff, B.-
item.contributorGout, O.-
item.contributorThouvenot, E.-
item.contributorHeinzlef, O.-
item.contributorAl-Khedr, A.-
item.contributorBourre, B.-
item.contributorCasez, O.-
item.contributorCabre, P.-
item.contributorMontcuquet, A.-
item.contributorWahab, A.-
item.contributorCamdessanche, J. P.-
item.contributorMaurousset, A.-
item.contributorBen Nasr, H.-
item.contributorHankiewicz, K.-
item.contributorPottier, C.-
item.contributorMaubeuge, N.-
item.contributorNifle, C.-
item.contributorLaplaud, D. A.-
item.contributorHorakova, D.-
item.contributorDimitri-Boulos, D.-
item.contributorHavrdova, E. K.-
item.contributorAlroughani, R.-
item.contributorIzquierdo, G.-
item.contributorEichau, S.-
item.contributorOzakbas, S.-
item.contributorPatti, F.-
item.contributorOnofrj, M.-
item.contributorLugaresi, A.-
item.contributorTerzi, M.-
item.contributorGrammond, P.-
item.contributorGrand'Maison, F.-
item.contributorYamout, B.-
item.contributorPrat, A.-
item.contributorGirard, M.-
item.contributorDuquette, P.-
item.contributorBoz, C.-
item.contributorTrojano, M.-
item.contributorMcCombe, P.-
item.contributorSlee, M.-
item.contributorLechner-Scott, J.-
item.contributorTurkoglu, R.-
item.contributorSola, P.-
item.contributorFerraro, D.-
item.contributorGranella, F.-
item.contributorShaygannejad, V-
item.contributorPrevost, J.-
item.contributorMaimone, D.-
item.contributorSkibina, O.-
item.contributorBuzzard, K.-
item.contributorVan der Walt, A.-
item.contributorKarabudak, R.-
item.contributorVAN WIJMEERSCH, Bart-
item.contributorCsepany, T.-
item.contributorSpitaleri, D.-
item.contributorVucic, S.-
item.contributorKoch-Henriksen, N.-
item.contributorSellebjerg, F.-
item.contributorSoerensen , P. S.-
item.contributorChristensen, C. C. Hilt-
item.contributorRasmussen, P., V-
item.contributorJensen, M. B.-
item.contributorFrederiksen, J. L.-
item.contributorBramow, S.-
item.contributorMathiesen, H. K.-
item.contributorSchreiber, K., I-
item.contributorButzkueven, H.-
item.contributorMagyari, M.-
item.contributorKalincik, T.-
item.contributorLeray, E.-
item.accessRightsOpen Access-
item.fullcitationLefort, M.; Sharmin , S.; Andersen, J. B.; Vukusic, S.; Casey, R.; Debouverie, M.; Edan, G.; Ciron, J.; Ruet, A.; De Seze, J.; Maillart, E.; Zephir, H.; Labauge, P.; Defer, G.; Lebrun-Frenay, C.; Moreau, T.; Berger , E.; Clavelou, P.; Pelletier, J.; Stankoff, B.; Gout, O.; Thouvenot, E.; Heinzlef, O.; Al-Khedr, A.; Bourre, B.; Casez, O.; Cabre, P.; Montcuquet, A.; Wahab, A.; Camdessanche, J. P.; Maurousset, A.; Ben Nasr, H.; Hankiewicz, K.; Pottier, C.; Maubeuge, N.; Nifle, C.; Laplaud, D. A.; Horakova, D.; Dimitri-Boulos, D.; Havrdova, E. K.; Alroughani, R.; Izquierdo, G.; Eichau, S.; Ozakbas, S.; Patti, F.; Onofrj, M.; Lugaresi, A.; Terzi, M.; Grammond, P.; Grand'Maison, F.; Yamout, B.; Prat, A.; Girard, M.; Duquette, P.; Boz, C.; Trojano, M.; McCombe, P.; Slee, M.; Lechner-Scott, J.; Turkoglu, R.; Sola, P.; Ferraro, D.; Granella, F.; Shaygannejad, V; Prevost, J.; Maimone, D.; Skibina, O.; Buzzard, K.; Van der Walt, A.; Karabudak, R.; VAN WIJMEERSCH, Bart; Csepany, T.; Spitaleri, D.; Vucic, S.; Koch-Henriksen, N.; Sellebjerg, F.; Soerensen , P. S.; Christensen, C. C. Hilt; Rasmussen, P., V; Jensen, M. B.; Frederiksen, J. L.; Bramow, S.; Mathiesen, H. K.; Schreiber, K., I; Butzkueven, H.; Magyari, M.; Kalincik, T. & Leray, E. (2022) Impact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis. In: BMC Medical research methodology (Online), 22 (1) (Art N° 155).-
item.fulltextWith Fulltext-
crisitem.journal.eissn1471-2288-
Appears in Collections:Research publications
Files in This Item:
File Description SizeFormat 
Impact of methodological choices in comparative effectiveness studies_ application in natalizumab versus fingolimod comparison among patients with multiple sclerosis.pdfPublished version1.31 MBAdobe PDFView/Open
Show simple item record

WEB OF SCIENCETM
Citations

3
checked on Apr 30, 2024

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.