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http://hdl.handle.net/1942/37635
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DC Field | Value | Language |
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dc.contributor.author | van't Hul, AJ | - |
dc.contributor.author | Koolen, EH | - |
dc.contributor.author | Antons, JC | - |
dc.contributor.author | de Man, M | - |
dc.contributor.author | Djamin, RS | - |
dc.contributor.author | in't Veen, JCCM | - |
dc.contributor.author | Simons, SO | - |
dc.contributor.author | van den Heuvel , M | - |
dc.contributor.author | van den Borst, B | - |
dc.contributor.author | SPRUIT, Martijn A. | - |
dc.date.accessioned | 2022-07-04T11:42:48Z | - |
dc.date.available | 2022-07-04T11:42:48Z | - |
dc.date.issued | 2020 | - |
dc.date.submitted | 2022-07-04T09:48:42Z | - |
dc.identifier.citation | ERJ open research, 6 (4) , p. 00438-2020 | - |
dc.identifier.uri | http://hdl.handle.net/1942/37635 | - |
dc.description.abstract | Introduction: The present study assessed the prevalence of nine treatable traits (TTs) pinpointing nonpharmacological interventions in patients with COPD upon first referral to a pulmonologist, how these TTs co-occurred and whether and to what extent the TTs increased the odds having a severely impaired health status.Methods: Data were collected from a sample of 402 COPD patients. A second sample of 381 patients with COPD was used for validation. Nine TTs were assessed: current smoking status, activity-related dyspnoea, frequent exacerbations <12 months, severe fatigue, depressed mood, poor physical capacity, low physical activity, poor nutritional status and a low level of self-management activation. For each TT the odds ratio (OR) of having a severe health status impairment was calculated. Furthermore, a graphic representation was created, the COPD sTRAITosphere, to visualise TTs prevalence and OR.Results: On average 3.9 +/- 2.0 TTs per patient were observed. These TTs occurred relatively independently of each other and coexisted in 151 unique combinations. A significant positive correlation was found between the number of TTs and Clinical COPD Questionnaire total score (r=0.58; p<0.001). Patients with severe fatigue (OR: 8.8), severe activity-related dyspnoea (OR: 5.8) or depressed mood (OR: 4.2) had the highest likelihood of having a severely impaired health status. The validation sample corroborated these findings.Conclusions: Upon first referral to a pulmonologist, COPD patients show multiple TTs indicating them to several nonpharmacological interventions. These TTs coexist in many different combinations, are relatively independent and increase the likelihood of having a severely impaired health status. | - |
dc.description.sponsorship | We would like to express our gratitude to all pulmonologists, respiratory nurses, pulmonary function technicians and workers of the clinometric department from both Bernhoven and Radboudumc who contributed to the collection of data for this study and for the interesting discussions we had during the process of explaining the results. | - |
dc.language.iso | en | - |
dc.publisher | EUROPEAN RESPIRATORY SOC JOURNALS LTD | - |
dc.rights | ERS 2020. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. | - |
dc.title | Treatable traits qualifying for nonpharmacological interventions in COPD patients upon first referral to a pulmonologist: the COPD sTRAITosphere | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 00438-2020 | - |
dc.identifier.volume | 6 | - |
local.bibliographicCitation.jcat | A1 | - |
local.publisher.place | 442 GLOSSOP RD, SHEFFIELD S10 2PX, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1183/23120541.00438-2020 | - |
dc.identifier.pmid | 33263050 | - |
dc.identifier.isi | 000603682700085 | - |
dc.identifier.eissn | - | |
local.provider.type | Web of Science | - |
local.uhasselt.international | yes | - |
item.fullcitation | van't Hul, AJ; Koolen, EH; Antons, JC; de Man, M; Djamin, RS; in't Veen, JCCM; Simons, SO; van den Heuvel , M; van den Borst, B & SPRUIT, Martijn A. (2020) Treatable traits qualifying for nonpharmacological interventions in COPD patients upon first referral to a pulmonologist: the COPD sTRAITosphere. In: ERJ open research, 6 (4) , p. 00438-2020. | - |
item.fulltext | With Fulltext | - |
item.validation | ecoom 2023 | - |
item.contributor | van't Hul, AJ | - |
item.contributor | Koolen, EH | - |
item.contributor | Antons, JC | - |
item.contributor | de Man, M | - |
item.contributor | Djamin, RS | - |
item.contributor | in't Veen, JCCM | - |
item.contributor | Simons, SO | - |
item.contributor | van den Heuvel , M | - |
item.contributor | van den Borst, B | - |
item.contributor | SPRUIT, Martijn A. | - |
item.accessRights | Open Access | - |
crisitem.journal.eissn | 2312-0541 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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00438-2020.full.pdf | Published version | 638.07 kB | Adobe PDF | View/Open |
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