Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/37671
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oulkadi, Sanad | - |
dc.contributor.author | PETERS, Benjamin | - |
dc.contributor.author | Vliegen, Anne-Sophie | - |
dc.date.accessioned | 2022-07-07T11:26:52Z | - |
dc.date.available | 2022-07-07T11:26:52Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2022-07-07T09:27:40Z | - |
dc.identifier.citation | JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 54 (4),p. 686-695 | - |
dc.identifier.uri | http://hdl.handle.net/1942/37671 | - |
dc.description.abstract | The recreatinal use of nitrous oxide has become more common in recent years, especially in adolescents and young adults. It has been mainly associated with medical conditions like megaloblastic anemia and (myelo)neuropathy. We report on the thromboembolic complications, a less known side effect, associated with recreational inhalation of nitrous oxide. An extensive literature search was performed for publications reporting on the thromboembolic complications associated with recreational nitrous oxide abuse. Data about sex, age, location of thrombosis, laboratory findings, therapy and outcome were collected. A total of 13 case reports or case series were identified comprising a total of 14 patients. The reported thromboembolic side effects included deep venous thrombosis, pulmonary embolism, mesenterial-, portal and splenic vein thrombosis, cerebral sinus thrombosis, cortical vein thrombosis, stroke, acute myocardial infarction and peripheral artery thromboembolism. These side effects are possibly mediated by the interaction of nitrous oxide with vitamin B12, a cofactor of the methionine synthase complex, which eventually results in elevation of plasma levels of homocysteine. Despite being a known risk factor for cardiovascular disease, the exact pathophysiological mechanism remains unclear. Cessation of nitrous oxide inhalation is necessary to prevent recurrent thrombosis. Nitrous oxide abuse may thus result in a wide spectrum of thromboembolic complications. One should be aware of this etiology, especially in a young person with no obvious risk factors for cardiovascular disease. Spreading awareness is important to inform people about the potentially serious side effects associated with nitrous oxide inhalation. | - |
dc.description.sponsorship | None to declare; this work is not funded by any third party | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.rights | The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022 | - |
dc.subject.other | Nitrous oxide abuse | - |
dc.subject.other | Thrombosis | - |
dc.subject.other | Embolism | - |
dc.subject.other | Hyperhomocysteinaemia | - |
dc.subject.other | Vitamin B12 | - |
dc.title | Thromboembolic complications of recreational nitrous oxide (ab)use: a systematic review | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 695 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 686 | - |
dc.identifier.volume | 54 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Oulkadi, S (corresponding author), Jessa Hosp, Dept Radiol, Resident Radiol, Hasselt, Belgium.; Oulkadi, S (corresponding author), Univ Antwerp, Fac Med & Hlth Sci, Antwerp, Belgium. | - |
dc.description.notes | sanadoulkadi@gmail.com | - |
local.publisher.place | VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
dc.identifier.doi | 10.1007/s11239-022-02673-x | - |
dc.identifier.pmid | 35759070 | - |
dc.identifier.isi | WOS:000816998000001 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Oulkadi, Sanad] Jessa Hosp, Dept Radiol, Resident Radiol, Hasselt, Belgium. | - |
local.description.affiliation | [Oulkadi, Sanad] Univ Antwerp, Fac Med & Hlth Sci, Antwerp, Belgium. | - |
local.description.affiliation | [Peters, Benjamin] Jessa Hosp, Cardiac Imaging, Dept Radiol, Hasselt, Belgium. | - |
local.description.affiliation | [Vliegen, Anne-Sophie] Jessa Hosp, Thorac Imaging, Dept Radiol, Hasselt, Belgium. | - |
local.uhasselt.international | no | - |
item.fullcitation | Oulkadi, Sanad; PETERS, Benjamin & Vliegen, Anne-Sophie (2022) Thromboembolic complications of recreational nitrous oxide (ab)use: a systematic review. In: JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 54 (4),p. 686-695. | - |
item.accessRights | Restricted Access | - |
item.fulltext | With Fulltext | - |
item.contributor | Oulkadi, Sanad | - |
item.contributor | PETERS, Benjamin | - |
item.contributor | Vliegen, Anne-Sophie | - |
crisitem.journal.issn | 0929-5305 | - |
crisitem.journal.eissn | 1573-742X | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
s11239-022-02673-x.pdf Restricted Access | Published version | 1.15 MB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.