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http://hdl.handle.net/1942/37700
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DC Field | Value | Language |
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dc.contributor.author | RAMARI FERREIRA, Cintia | - |
dc.contributor.author | Hvid, Lars G. | - |
dc.contributor.author | Dalgas, Ulrik | - |
dc.contributor.author | Diniz, Ana R. | - |
dc.contributor.author | von Glehn, Felipe | - |
dc.contributor.author | de David, Ana C. | - |
dc.date.accessioned | 2022-07-13T07:06:43Z | - |
dc.date.available | 2022-07-13T07:06:43Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2022-07-07T09:25:55Z | - |
dc.identifier.citation | Clinical biomechanics (Bristol), 96 (Art N° 105668) | - |
dc.identifier.uri | http://hdl.handle.net/1942/37700 | - |
dc.description.abstract | Background: Limitations in physical function are common in Multiple Sclerosis (MS), yet it is neither clear how muscle power implicates physical function and walking-fatigability. This pilot-study aims to investigate (1) deficits in muscle power/force alongside walking in persons with MS; (2) associations between muscle power/ force and physical functions and (3) the impact of prolonged walking in muscle power/force. Methods: 30 relapse-remitting persons with MS and 28 healthy controls performed chair rise and plantar flexion on a force platform before and after 12-minutes of intermittent walking to measure lower extremity muscle power/force. GaitRite measured walking speed. The percentage change in distance walked was also calculated. Persons with MS were classified into subgroups according to walking-fatigability and mobility disability status (Patient Determined Disease Steps). Findings: Higher deficits in muscle power compared to force were observed in persons with MS vs. healthy controls particularly in persons with MS having higher disability. Muscle power and force were associated with walking capacity, mobility disability and subjective fatigue, but not with percentage change in distance walked. Persons with MS slowed down over the course of the 12-min intermittent walking, whereas decrements in walking speed and muscle power/force (derived from chair rise) were observed in persons with MS presenting walking-fatigability only. Interpretation: Muscle power and force are impaired in persons with MS and appear to be critical for physical function in MS. This exploratory pilot study further suggests that muscle power/force from chair rise could contributes to walking-fatigability which therefore offer future treatment targets. | - |
dc.description.sponsorship | This work was partially funded by the Coordination for the Improvement of Higher Education (CAPES, Brazil – Finance Code 001). We thank the neurologists Carlos Bernardo Tauil and Eber Castro Correa for the assistance with inviting the patients from their private clinics to participate in this study, and the Apemigos (Association of People with Multiple Sclerosis from the Federal District) for encouraging the participants to contribute with the multiple sclerosis research projects. At last, we thank all the participants. | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.rights | 2022 Elsevier Ltd. All rights reserved. | - |
dc.subject.other | Multiple sclerosis | - |
dc.subject.other | Functional capacity | - |
dc.subject.other | Fatigue | - |
dc.subject.other | Muscle function | - |
dc.subject.other | Walking | - |
dc.subject.other | Disability | - |
dc.title | Implications of lower extremity muscle power and force for walking and fatigability in multiple sclerosis-An exploratory pilot-study | - |
dc.type | Journal Contribution | - |
dc.identifier.volume | 96 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Ramari, C (corresponding author), Hasselt Univ, REVAL Rehabil Res Ctr, Fac Rehabil Sci, Hasselt, Belgium. | - |
dc.description.notes | cintia.ramariferreira@uhasselt.be | - |
local.publisher.place | THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 105668 | - |
dc.identifier.doi | 10.1016/j.clinbiomech.2022.105668 | - |
dc.identifier.pmid | 35594782 | - |
dc.identifier.isi | WOS:000804741800007 | - |
dc.contributor.orcid | Dalgas, Ulrik/0000-0003-4132-2789; G Hvid, Lars/0000-0003-3233-0429 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Ramari, Cintia; de David, Ana C.] Univ Brasilia, Fac Phys Educ, Brasilia, DF, Brazil. | - |
local.description.affiliation | [Ramari, Cintia] Hasselt Univ, REVAL Rehabil Res Ctr, Fac Rehabil Sci, Hasselt, Belgium. | - |
local.description.affiliation | [Hvid, Lars G.; Dalgas, Ulrik] Aarhus Univ, Dept Publ Hlth, Exercise Biol, Aarhus, Denmark. | - |
local.description.affiliation | [Hvid, Lars G.] Danish MS Hosp, Ry, Denmark. | - |
local.description.affiliation | [Hvid, Lars G.] Danish MS Hosp, Haslev, Denmark. | - |
local.description.affiliation | [Diniz, Ana R.; de David, Ana C.] Univ Brasilia, Fac Ceilandia, Brasilia, DF, Brazil. | - |
local.description.affiliation | [von Glehn, Felipe] Univ Brasilia, Fac Med, Brasilia, DF, Brazil. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.fullcitation | RAMARI FERREIRA, Cintia; Hvid, Lars G.; Dalgas, Ulrik; Diniz, Ana R.; von Glehn, Felipe & de David, Ana C. (2022) Implications of lower extremity muscle power and force for walking and fatigability in multiple sclerosis-An exploratory pilot-study. In: Clinical biomechanics (Bristol), 96 (Art N° 105668). | - |
item.contributor | RAMARI FERREIRA, Cintia | - |
item.contributor | Hvid, Lars G. | - |
item.contributor | Dalgas, Ulrik | - |
item.contributor | Diniz, Ana R. | - |
item.contributor | von Glehn, Felipe | - |
item.contributor | de David, Ana C. | - |
item.accessRights | Open Access | - |
item.validation | ecoom 2023 | - |
crisitem.journal.issn | 0268-0033 | - |
crisitem.journal.eissn | 1879-1271 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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Implications of lower extremity muscle power and force for walking and fatigability in multiple sclerosis – An exploratory pilot-study.pdf Restricted Access | Published version | 1.01 MB | Adobe PDF | View/Open Request a copy |
Ramari 2022.pdf | Peer-reviewed author version | 412.07 kB | Adobe PDF | View/Open |
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