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Title: | Virologic suppression and associated factors in HIV infected Ugandan female sex workers: a cross-sectional study | Authors: | Owachi, D Anguzu, G Kigozi, J COX, Janneke Castelnuovo, B Semitala, F Meya, D |
Issue Date: | 2021 | Publisher: | MAKERERE UNIV, COLL HEALTH SCIENCES,SCH MED | Source: | African health sciences (Print), 21 (2) , p. 603 -613 | Abstract: | Introduction: Key populations have disproportionately higher HIV prevalence rates than the general population.Objective: To determine the level of virologic suppression and associated factors in female Commercial Sex Workers (CSW) who completed six months of ART and compare with the female general population (GP).Methods: Clinical records of CSW and GPs who initiated ART between December 2014 to December 2016 from seven urban clinics were analyzed to determine virologic suppression (viral load < 1000 copies/ml) and associated factors.Results: We identified 218 CSW and 182 female GPs. CSW had median age of 28 (IQR 25-31) vs 31 (IQR 26-37); median baseline CD4 446 (IQR 308-696) vs 352 (IQR 164-493) cells/microL; and optimal ART adherence levels at 70.6% vs 92.8% respectively, compared to GP. Virologic suppression in CSW and GPs was 85.7% and 89.6% respectively, P=0.28. Overall virologic suppression in CSW was 55% while Retention in care after 6 months of ART was 77.5%. Immediate ART initiation (<2weeks) and tuberculosis independently predicted virologic suppression in CSW with adjusted odds ratios 0.07 (95% C.I. 0.01-0.55, P=0.01) and 0.09 (95% C.I. 0.01-0.96, P=0.046) respectively.Conclusion: Virologic suppression in both groups is similar, however, intensified follow-up is needed to improve treatment outcomes. | Keywords: | Adult;Cross-Sectional Studies;Female;HIV Infections;Health Services Accessibility;Humans;Medication Adherence;Sex Workers;Uganda;Viral Load;Antiretroviral Therapy, Highly Active | Document URI: | http://hdl.handle.net/1942/37709 | ISSN: | 1680-6905 | e-ISSN: | 1729-0503 | DOI: | 10.4314/ahs.v21i2.15 | ISI #: | 000750856500003 | Rights: | 2021Owachi D et al. Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | Category: | A1 | Type: | Journal Contribution |
Appears in Collections: | Research publications |
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