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Title: | Association between incident falls and subsequent fractures in patients attending the fracture liaison service after an index fracture: a 3-year prospective observational cohort study | Authors: | Vranken, Lisanne Wyers, Caroline E. Van der Velde, Robert Y. Janzing, Heinrich M. J. Kaarsemakers, Sjoerd Driessen, Johanna Eisman, John Center, Jacqueline R. Nguyen, Tuan, V Tran , Thach Bliuc, Dana GEUSENS, Piet VAN DEN BERGH, Joop |
Issue Date: | 2022 | Publisher: | BMJ PUBLISHING GROUP | Source: | BMJ open, 12 (7) (Art N° e058983) | Abstract: | Objectives To evaluate the risk of subsequent fractures in patients who attended the Fracture Liaison Service (FLS), with and without incident falls after the index fracture. Design A 3-year prospective observational cohort study. Setting An outpatient FLS in the Netherlands. Participants Patients aged 50+ years with a recent clinical fracture. Outcome measures Incident falls and subsequent fractures. Results The study included 488 patients (71.9% women, mean age: 64.6 +/- 8.6 years). During the 3-year follow-up, 959 falls had been ascertained in 296 patients (60.7%) (ie, fallers), and 60 subsequent fractures were ascertained in 53 patients (10.9%). Of the fractures, 47 (78.3%) were fall related, of which 25 (53.2%) were sustained at the first fall incident at a median of 34 weeks. An incident fall was associated with an approximately 9-fold (HR: 8.6, 95% CI 3.1 to 23.8) increase in the risk of subsequent fractures. Conclusion These data suggest that subsequent fractures among patients on treatment prescribed in an FLS setting are common, and that an incident fall is a strong predictor of subsequent fracture risk. Immediate attention for fall risk could be beneficial in an FLS model of care. | Notes: | van den Bergh, JP (corresponding author), VieCuri Med Ctr, Dept Internal Med, Venlo, Netherlands.; van den Bergh, JP (corresponding author), Maastricht Univ, Med Ctr, Res Sch NUTRIM, Dept Internal Med, Maastricht, Netherlands. jvdbergh@viecuri.nl |
Keywords: | internal medicine;orthopaedic & trauma surgery;general medicine (see Internal Medicine) | Document URI: | http://hdl.handle.net/1942/38018 | ISSN: | 2044-6055 | e-ISSN: | 2044-6055 | DOI: | 10.1136/bmjopen-2021-058983 | ISI #: | 000832651800015 | Rights: | Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Open access This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2023 |
Appears in Collections: | Research publications |
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