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http://hdl.handle.net/1942/38085
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DC Field | Value | Language |
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dc.contributor.author | Song, James | - |
dc.contributor.author | VERBEECK, Johan | - |
dc.contributor.author | Huang , Bo | - |
dc.contributor.author | Hoaglin, David C. | - |
dc.contributor.author | Gamalo-Siebers, Margaret | - |
dc.contributor.author | Seifu, Yodit | - |
dc.contributor.author | Wang, Duolao | - |
dc.contributor.author | Cooner, Freda | - |
dc.contributor.author | Dong, Gaohong | - |
dc.date.accessioned | 2022-09-15T07:20:21Z | - |
dc.date.available | 2022-09-15T07:20:21Z | - |
dc.date.issued | 2023 | - |
dc.date.submitted | 2022-08-25T09:11:42Z | - |
dc.identifier.citation | Journal of biopharmaceutical statistics (Print), 33 (2), p. 140-150 | - |
dc.identifier.uri | http://hdl.handle.net/1942/38085 | - |
dc.description.abstract | Generalized pairwise comparisons and win statistics (i.e., win ratio, win odds and net benefit) are advantageous in analyzing and interpreting a composite of multiple outcomes in clinical trials. An important limitation of these statistics is their inability to adjust for covariates other than by stratified analysis. Because the win ratio does not account for ties, the win odds, a modification that includes ties, has attracted attention. We review and combine information on the win odds to articulate the statistical inferences for the win odds. We also show alternative variance estimators based on the exact permutation and bootstrap as well as statistical inference via the probabilistic index. Finally, we extend multiple-covariate regression probabilistic index models to the win odds with a univariate outcome. As an illustration we apply the regression models to the data in the CHARM trial. | - |
dc.description.sponsorship | The author(s) reported there is no funding associated with the work featured in this article. | - |
dc.language.iso | en | - |
dc.publisher | TAYLOR & FRANCIS INC | - |
dc.rights | 2022 Taylor & Francis Group, LLC | - |
dc.subject.other | Win ratio | - |
dc.subject.other | win odds | - |
dc.subject.other | net benefit | - |
dc.subject.other | win statistics | - |
dc.subject.other | probabilistic index model | - |
dc.subject.other | bootstrap | - |
dc.subject.other | permutation | - |
dc.title | The win odds: statistical inference and regression | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 150 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 140 | - |
dc.identifier.volume | 33 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Song, J (corresponding author), BeiGene, Ridgefield Pk, NJ 07660 USA. | - |
dc.description.notes | james.song@beigene.com | - |
local.publisher.place | 530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1080/10543406.2022.2089156 | - |
dc.identifier.pmid | 35946932 | - |
dc.identifier.isi | 000838600800001 | - |
dc.contributor.orcid | Hoaglin, David/0000-0003-1336-181X; Dong, Gaohong/0000-0002-9848-1329; | - |
dc.contributor.orcid | Wang, Duolao/0000-0003-2788-2464; Verbeeck, Johan/0000-0002-4923-1032 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Song, James; Dong, Gaohong] BeiGene, Ridgefield Pk, NJ 07660 USA. | - |
local.description.affiliation | [Verbeeck, Johan] Univ Hasselt, I Biostat, DSI, Hasselt, Belgium. | - |
local.description.affiliation | [Huang, Bo] Pfizer Inc, Groton, CT 06340 USA. | - |
local.description.affiliation | [Hoaglin, David C.] UMass Chan Med Sch, Dept Populat & Quantitat Hlth Sci, Worcester, MA USA. | - |
local.description.affiliation | [Gamalo-Siebers, Margaret] Pfizer Inc, Collegeville, PA USA. | - |
local.description.affiliation | [Seifu, Yodit] Bristol Myers Squibb, New York, NJ USA. | - |
local.description.affiliation | [Wang, Duolao] Univ Liverpool Liverpool Sch Trop Med, Liverpool, Merseyside, England. | - |
local.description.affiliation | [Cooner, Freda] Amgen Inc, Thousand Oaks, CA USA. | - |
local.uhasselt.international | yes | - |
item.fullcitation | Song, James; VERBEECK, Johan; Huang , Bo; Hoaglin, David C.; Gamalo-Siebers, Margaret; Seifu, Yodit; Wang, Duolao; Cooner, Freda & Dong, Gaohong (2023) The win odds: statistical inference and regression. In: Journal of biopharmaceutical statistics (Print), 33 (2), p. 140-150. | - |
item.validation | ecoom 2023 | - |
item.accessRights | Open Access | - |
item.fulltext | With Fulltext | - |
item.contributor | Song, James | - |
item.contributor | VERBEECK, Johan | - |
item.contributor | Huang , Bo | - |
item.contributor | Hoaglin, David C. | - |
item.contributor | Gamalo-Siebers, Margaret | - |
item.contributor | Seifu, Yodit | - |
item.contributor | Wang, Duolao | - |
item.contributor | Cooner, Freda | - |
item.contributor | Dong, Gaohong | - |
crisitem.journal.issn | 1054-3406 | - |
crisitem.journal.eissn | 1520-5711 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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Microsoft Word - WO_revised__2__Final2.pdf | Peer-reviewed author version | 916.84 kB | Adobe PDF | View/Open |
The win odds_ statistical inference and regression.pdf Restricted Access | Published version | 903.83 kB | Adobe PDF | View/Open Request a copy |
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