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Title: | Heart failure during the COVID-19 pandemic: clinical, diagnostic, management, and organizational dilemmas | Authors: | Palazzuoli, Alberto Metra, Marco Collins, Sean P. Adamo, Marianna Ambrosy, Andrew P. Antohi, Laura E. Ben Gal, Tuvia Farmakis, Dimitrios Gustafsson, Finn Hill, Loreena Lopatin, Yuri Tramonte, Francesco Lyon, Alexander Masip, Josep Miro, Oscar Moura, Brenda MULLENS, Wilfried Radu, Razvan, I Abdelhamid, Magdy Anker, Stefan Chioncel, Ovidiu |
Issue Date: | 2022 | Publisher: | WILEY PERIODICALS, INC | Source: | ESC Heart Failure, 9 (6), P. 3713-3736 | Abstract: | The coronavirus 2019 (COVID-19) infection pandemic has affected the care of patients with heart failure (HF). Several consensus documents describe the appropriate diagnostic algorithm and treatment approach for patients with HF and associated COVID-19 infection. However, few questions about the mechanisms by which COVID can exacerbate HF in patients with high-risk (Stage B) or symptomatic HF (Stage C) remain unanswered. Therefore, the type of HF occurring during infection is poorly investigated. The diagnostic differentiation and management should be focused on the identification of the HF phenotype, underlying causes, and subsequent tailored therapy. In this framework, the relationship existing between COVID and onset of acute decompensated HF, isolated right HF, and cardiogenic shock is questioned, and the specific management is mainly based on local hospital organization rather than a standardized model. Similarly, some specific populations such as advanced HF, heart transplant, patients with left ventricular assist device (LVAD), or valve disease remain under investigated. In this systematic review, we examine recent advances regarding the relationships between HF and COVID-19 pandemic with respect to epidemiology, pathogenetic mechanisms, and differential diagnosis. Also, according to the recent HF guidelines definition, we highlight different clinical profile identification, pointing out the main concerns in understudied HF populations. | Notes: | Palazzuoli, A (corresponding author), Univ Siena, S Maria Alle Scotte Hosp, Cardio Thorac & Vasc Dept, Cardiovasc Dis Unit, I-53100 Siena, Italy. palazzuoli2@unisi.it |
Keywords: | COVID-19;Heart failure;Diagnostic differentiation;Management | Document URI: | http://hdl.handle.net/1942/38688 | ISSN: | 2055-5822 | e-ISSN: | 2055-5822 | DOI: | 10.1002/ehf2.14118 | ISI #: | 000854081300001 | Rights: | © 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2023 |
Appears in Collections: | Research publications |
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Heart failure during the COVID‐19 pandemic_ clinical, diagnostic, management, and organizational dilemmas.pdf | Published version | 1.24 MB | Adobe PDF | View/Open |
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