Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/38862
Title: | Public and occupational health risks related to lead exposure updated according to present-day blood lead levels | Authors: | Yu, Yu-Ling Yang, Wen-Yi Hara, Azusa Asayama, Kei ROELS, Harry NAWROT, Tim Staessen, Jan A. |
Issue Date: | 2022 | Publisher: | SPRINGERNATURE | Source: | HYPERTENSION RESEARCH, 46 (2), p. 395-407 | Abstract: | Lead is an environmental hazard that should be addressed worldwide. Over time, human lead exposure in the western world has decreased drastically to levels comparable to those among humans living in the preindustrial era, who were mainly exposed to natural sources of lead. To re-evaluate the potential health risks associated with present-day lead exposure, a two-pronged approach was applied. First, recently published population metrics describing the adverse health effects associated with lead exposure at the population level were critically assessed. Next, the key results of the Study for Promotion of Health in Recycling Lead (SPHERL; NCT02243904) were summarized and put in perspective with those of the published population metrics. To our knowledge, SPHERL is the first prospective study that accounted for interindividual variability between people with respect to their vulnerability to the toxic effects of lead exposure by assessing the participants' health status before and after occupational lead exposure. The overall conclusion of this comprehensive review is that mainstream ideas about the public and occupational health risks related to lead exposure urgently need to be updated because a large portion of the available literature became obsolete given the sharp decrease in exposure levels over the past 40 years. | Notes: | Staessen, JA (corresponding author), Nonprofit Res Assoc Alliance Promot Prevent Med, Mechelen, Belgium.; Staessen, JA (corresponding author), Univ Leuven, Fac Med, Biomed Sci Grp, Leuven, Belgium. jan.staessen@appremed.org |
Keywords: | Environmental medicine;Hypertension;Lead;Mortality;Occupational medicine | Document URI: | http://hdl.handle.net/1942/38862 | ISSN: | 0916-9636 | e-ISSN: | 1348-4214 | DOI: | 10.1038/s41440-022-01069-x | ISI #: | 000869586700001 | Rights: | The Author(s) 2022. This article is published with open access | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2023 |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Public and occupational health risks related to lead exposure updated according to present-day blood lead levels.pdf | Published version | 1.92 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.