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Title: | Isokinetic testing of quadriceps function in COPD: feasibility, responsiveness, and minimal important differences in patients undergoing pulmonary rehabilitation | Authors: | Stoffels, Anouk A. F. Meys, Roy Hees, Hieronymus W. H. van Franssen, Frits M. E. Borst, Bram van den Hul, Alex J. van 't Klijn, Peter H. Vaes, Anouk W. DE BRANDT, Jana BURTIN, Chris SPRUIT, Martijn A. BASES-consortium, BASES-consortium |
Issue Date: | 2022 | Publisher: | ASSOCIACAO BRASILEIRA PESQUISA POS-GRADUACAO FISIOTERAPIA-ABRAPG-FT | Source: | Brazilian Journal of Physical Therapy, 26 (5) (Art N° 100451) | Abstract: | Background: Isokinetic testing of peripheral muscle function is valid and reliable in patients with chronic obstructive pulmonary disease (COPD).Objective: To evaluate whether and to what extent isokinetic testing of quadriceps function meets pre-defined test criteria in patients with COPD; to determine the response to pulmonary rehabilitation (PR), and to calculate minimal important differences (MIDs) of isokinetic quadri-ceps function.Methods: Retrospective analysis of 2033 patients with COPD (age: 65 +/- 9 years, body mass index: 26 +/- 6 kg/m2, FEV1: 49 +/- 22% predicted) who followed a comprehensive PR program. Pre and post PR isokinetic quadriceps function was assessed with 30 maximal extension -flexion contractions at an angular speed of 90 degrees/s on a computerized dynamometer. The chosen anchors were 6-min walk test and COPD assessment test.Results: Pre PR, 27% of the patients performed the isokinetic test incorrectly. In male and female patients with a correct pre and post PR isokinetic test, peak torque (A=10 +/- 13 Nm or 9% and A=7 +/- 9 Nm or 10%, respectively) and total work (A=263 +/- 270 J or 14% and A=198 +/- 190 J or 15%, respectively) improved significantly. There was no change in work fatigue index following PR. Using distribution-based calculations, MID estimates for peak torque and total work ranged between 6-7 Nm and 97-135 J in males and between 4-5 Nm and 62-99 J in females.Conclusions: Based on the current test criteria, three in four patients with COPD performed the isokinetic quadriceps test correctly during baseline PR assessment. Furthermore, peak torque and total work, but not work fatigue index, were responsive to PR and sex-specific MIDs were established.(c) 2022 The Author(s). Published by Elsevier Espana, S.L.U. on behalf of Associacao Brasileira de Pesquisa e Pos-Graduacao em Fisioterapia. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | Notes: | Stoffels, AAF (corresponding author), Radboud Univ Nijmegen, Med Ctr, Dept Pulm Dis, NL-6500 HB Nijmegen, Netherlands. anouk.stoffels@radboudumc.nl |
Keywords: | Minimal important difference;Muscles;Quadriceps;Rehabilitation;Chronic obstructive pulmonary disease | Document URI: | http://hdl.handle.net/1942/38928 | ISSN: | 1413-3555 | e-ISSN: | 1809-9246 | DOI: | 10.1016/j.bjpt.2022.100451 | ISI #: | 000879416300001 | Rights: | 2022 The Author(s). Published by Elsevier España, S.L.U. on behalf of Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2023 |
Appears in Collections: | Research publications |
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