Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/38950
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Singh, Gurpreet K. | - |
dc.contributor.author | Vollema, E. Mara | - |
dc.contributor.author | STASSEN, Jan | - |
dc.contributor.author | van Rosendael, Alexander | - |
dc.contributor.author | Gegenava, Tea | - |
dc.contributor.author | van der Kley, Frank | - |
dc.contributor.author | Knuuti, Juhani | - |
dc.contributor.author | Marsan, Nina Ajmone | - |
dc.contributor.author | Delgado, Victoria | - |
dc.contributor.author | Bax, Jeroen J. | - |
dc.date.accessioned | 2022-11-30T07:48:44Z | - |
dc.date.available | 2022-11-30T07:48:44Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2022-11-25T10:31:31Z | - |
dc.identifier.citation | AMERICAN JOURNAL OF CARDIOLOGY, 182 , p. 83 -88 | - |
dc.identifier.uri | http://hdl.handle.net/1942/38950 | - |
dc.description.abstract | Several studies have shown an association between aortic stenosis (AS) and coronary atherosclerosis. This study aimed to evaluate the gender differences in aortic valve calcium (AVC) and coronary artery calcium (CAC) and the association between CAC and allcause mortality in patients with severe AS. A total of 260 patients (80 </n> 7 years, 39% men) with severe AS who were scheduled for transcatheter aortic valve implantation (TAVI) were included. AVC and CAC before TAVI were assessed by noncontrast cardiac computed tomography. Patients with coronary intervention or aortic valve replacement before cardiac computed tomography were excluded. Standard reference values of CAC score were used to classify the percentile groups and the distribution of AVC was assessed. The primary end point was all-cause mortality. In men, the AVC score was 3,911 Hounsfield units (HUs) (interquartile range [IQR] 2,525 to 5,259) and in women, 2,409 HU (IQR 1,588 to 3,359) (p <0.001). CAC score in men was 824 HU (IQR 328 to 1,855) and in women, 478 HU (IQR 136 to 962) (p <0.001). In men, the AVC score increased along with the CAC score, whereas in women, the AVC score was similar across the CAC percentile groups. During a median follow-up of 1,095 days, 59 patients (23%) died. No significant gender-difference was seen in all-cause mortality for CAC score (p = 0.187). Men with severe AS show higher AVC and CAC scores than women. Although the pattern of CAC distribution was similar between men and women, the AVC score increased along with the CAC score in men; whereas, in women, the AVC score remained similar across the various percentiles. CAC score was not associated with cumulative mortality in patients with severe AS who underwent TAVI. (c) 2022 Published by Elsevier Inc. (Am J Cardiol 2022;182:83-88) | - |
dc.description.sponsorship | The department of Cardiology of the Leiden University Medical Center received research grants from Abbott Vascular, Bayer, Bioventrix, Biotronik, Boston Scientific, Edwards Lifesciences, GE Healthcare, and Medtronic. Dr. Delgado received speaker fees from Abbott Vascular, Edward Lifesciences, GE Healthcare, MSD, and Medtronic. Dr. Marsan received speaker fees from Abbott Vascular and GE Healthcare. Dr. Bax received speaker fees from Abbott Vascular. The remaining authors have no conflicts of interest to declare. | - |
dc.language.iso | en | - |
dc.publisher | EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC | - |
dc.rights | 2023 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/ 4.0/) (Am J Cardiol 2022;182:83−88) | - |
dc.subject.other | Aortic Valve | - |
dc.subject.other | Calcium | - |
dc.subject.other | Coronary Vessels | - |
dc.subject.other | Female | - |
dc.subject.other | Humans | - |
dc.subject.other | Male | - |
dc.subject.other | Severity of Illness Index | - |
dc.subject.other | Aortic Valve Stenosis | - |
dc.subject.other | Calcinosis | - |
dc.subject.other | Transcatheter Aortic Valve Replacement | - |
dc.title | Comparison of the Quantity of Calcium in the Aortic Valve and the Coronary Arteries in Men Versus Women Who Underwent Transcatheter Aortic Valve Implantation | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 88 | - |
dc.identifier.spage | 83 | - |
dc.identifier.volume | 182 | - |
local.format.pages | 6 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Bax, JJ (corresponding author), Leiden Univ, Dept Cardiol, Med Ctr, Leiden, Netherlands.; Bax, JJ (corresponding author), Univ Turku, Turku Heart Ctr, Turku, Finland.; Bax, JJ (corresponding author), Turku Univ Hosp, Turku, Finland. | - |
dc.description.notes | j.j.bax@lumc.nl | - |
local.publisher.place | 685 ROUTE 202-206 STE 3, BRIDGEWATER, NJ 08807 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.amjcard.2022.07.008 | - |
dc.identifier.pmid | 36049969 | - |
dc.identifier.isi | 000880643200005 | - |
dc.contributor.orcid | Singh, Gurpreet Kaur/0000-0002-6722-4661; Knuuti, | - |
dc.contributor.orcid | Juhani/0000-0003-3156-9593; Bax, Jeroen/0000-0001-7368-0500 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Singh, Gurpreet K.; Stassen, Jan; van Rosendael, Alexander; Gegenava, Tea; van der Kley, Frank; Marsan, Nina Ajmone; Delgado, Victoria; Bax, Jeroen J.] Leiden Univ, Dept Cardiol, Med Ctr, Leiden, Netherlands. | - |
local.description.affiliation | [Stassen, Jan] Jessa Hosp, Dept Cardiol, Hasselt, Belgium. | - |
local.description.affiliation | [Delgado, Victoria] Hosp Badalona Germans Trias & Pujol, Heart Inst, Badalona, Spain. | - |
local.description.affiliation | [Bax, Jeroen J.] Univ Turku, Turku Heart Ctr, Turku, Finland. | - |
local.description.affiliation | [Bax, Jeroen J.] Turku Univ Hosp, Turku, Finland. | - |
local.uhasselt.international | yes | - |
item.accessRights | Open Access | - |
item.contributor | Singh, Gurpreet K. | - |
item.contributor | Vollema, E. Mara | - |
item.contributor | STASSEN, Jan | - |
item.contributor | van Rosendael, Alexander | - |
item.contributor | Gegenava, Tea | - |
item.contributor | van der Kley, Frank | - |
item.contributor | Knuuti, Juhani | - |
item.contributor | Marsan, Nina Ajmone | - |
item.contributor | Delgado, Victoria | - |
item.contributor | Bax, Jeroen J. | - |
item.fulltext | With Fulltext | - |
item.fullcitation | Singh, Gurpreet K.; Vollema, E. Mara; STASSEN, Jan; van Rosendael, Alexander; Gegenava, Tea; van der Kley, Frank; Knuuti, Juhani; Marsan, Nina Ajmone; Delgado, Victoria & Bax, Jeroen J. (2022) Comparison of the Quantity of Calcium in the Aortic Valve and the Coronary Arteries in Men Versus Women Who Underwent Transcatheter Aortic Valve Implantation. In: AMERICAN JOURNAL OF CARDIOLOGY, 182 , p. 83 -88. | - |
crisitem.journal.issn | 0002-9149 | - |
crisitem.journal.eissn | 1879-1913 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Comparison of the Quantity of Calcium in the Aortic Valve and the Coronary Arteries in Men Versus Women Who Underwent Transcatheter Aortic Valve Implantation.pdf | Published version | 614.14 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.