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http://hdl.handle.net/1942/39022
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DC Field | Value | Language |
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dc.contributor.author | BONNECHERE, Bruno | - |
dc.contributor.author | Amin, Najaf | - |
dc.contributor.author | VAN DUIJN, Cornelia | - |
dc.date.accessioned | 2022-12-12T15:43:02Z | - |
dc.date.available | 2022-12-12T15:43:02Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2022-12-05T11:13:15Z | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (22) (Art N° 13665) | - |
dc.identifier.uri | http://hdl.handle.net/1942/39022 | - |
dc.description.abstract | There is a growing body of evidence highlighting there are significant changes in the gut microbiota composition and relative abundance in various neurological disorders. We performed a systematic review of the different microbiota altered in a wide range of neurological disorders (Alzheimer's disease (AD), Parkinson's disease (PD), multiple sclerosis (MS), amyotrophic lateral sclerosis, and stroke). Fifty-two studies were included representing 5496 patients. At the genus level, the most frequently involved microbiota are Akkermansia, Faecalibacterium, and Prevotella. The overlap between the pathologies was strongest for MS and PD, sharing eight genera (Akkermansia, Butyricicoccus, Bifidobacterium, Coprococcus, Dorea, Faecalibacterium, Parabacteroides, and Prevotella) and PD and stroke, sharing six genera (Enterococcus, Faecalibacterium, Lactobacillus, Parabacteroides, Prevotella, and Roseburia). The identification signatures overlapping for AD, PD, and MS raise the question of whether these reflect a common etiology or rather common consequence of these diseases. The interpretation is hampered by the low number and low power for AD, ALS, and stroke with ample opportunity for false positive and false negative findings. | - |
dc.language.iso | en | - |
dc.publisher | - | |
dc.rights | 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). | - |
dc.subject.other | Alzheimer’s disease | - |
dc.subject.other | Parkinson’s disease | - |
dc.subject.other | atrophic lateral sclerosis | - |
dc.subject.other | gut microbiome | - |
dc.subject.other | multiple sclerosis | - |
dc.subject.other | stroke | - |
dc.subject.other | Humans | - |
dc.subject.other | Akkermansia | - |
dc.subject.other | Prevotella | - |
dc.subject.other | Clostridiaceae | - |
dc.subject.other | Clostridiales | - |
dc.subject.other | Gastrointestinal Microbiome | - |
dc.subject.other | Nervous System Diseases | - |
dc.subject.other | Parkinson Disease | - |
dc.subject.other | Microbiota | - |
dc.subject.other | Multiple Sclerosis | - |
dc.subject.other | Stroke | - |
dc.title | What Are the Key Gut Microbiota Involved in Neurological Diseases? A Systematic Review | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 22 | - |
dc.identifier.volume | 23 | - |
local.bibliographicCitation.jcat | A1 | - |
local.publisher.place | ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
local.bibliographicCitation.artnr | 13665 | - |
dc.identifier.doi | 10.3390/ijms232213665 | - |
dc.identifier.pmid | 36430144 | - |
dc.identifier.isi | 000887481700001 | - |
local.provider.type | PubMed | - |
local.uhasselt.international | yes | - |
item.validation | ecoom 2023 | - |
item.contributor | BONNECHERE, Bruno | - |
item.contributor | Amin, Najaf | - |
item.contributor | VAN DUIJN, Cornelia | - |
item.accessRights | Open Access | - |
item.fullcitation | BONNECHERE, Bruno; Amin, Najaf & VAN DUIJN, Cornelia (2022) What Are the Key Gut Microbiota Involved in Neurological Diseases? A Systematic Review. In: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (22) (Art N° 13665). | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 1661-6596 | - |
crisitem.journal.eissn | 1422-0067 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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ijms-23-13665-v2.pdf | Published version | 5.26 MB | Adobe PDF | View/Open |
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