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http://hdl.handle.net/1942/39067
Title: | End‑Tidal CO2 in Patients with Panic Disorder, Stress‑Related or Functional Syndromes, Versus Healthy Controls | Authors: | RAMAKERS, Indra VAN DEN HOUTE, Maaike Van Oudenhove, Lukas Van den Bergh, Omer BOGAERTS, Katleen |
Issue Date: | 2022 | Publisher: | Source: | APPLIED PSYCHOPHYSIOLOGY AND BIOFEEDBACK, | Status: | Early view | Abstract: | A dysregulated autonomic stress physiology is hypothesized to play an important role in the etiology and perpetuation of somatic symptoms that cannot be (fully) explained by an organic disease. The aim of this study was to focus on the role of the respiratory system. We examined end-tidal CO2 concentration (PetCO2) in healthy controls (n=30), patients with panic disorder (n=36), and patients with stress-related (overstrain; n=35, burnout; n=44) or functional syndromes [fbromyalgia (FM) and/or chronic fatigue syndrome (CFS); n=36]. Participants went through a rest period and a respiratory challenge with recovery, whilst PetCO2 was continuously monitored by a capnograph. Taken together, our results suggest: (1) an overactive respiratory system to be a possible transdiagnostic underlying factor of overstrain, burnout, and panic disorder, and (2) the presence of a less active respiratory fght-fight response in the more chronic and severe functional syndromes (FM/CFS). | Keywords: | Stress;Panic disorder;Psychophysiology;Functional syndrome;Burnout;PetCO2 | Document URI: | http://hdl.handle.net/1942/39067 | ISSN: | 1090-0586 | e-ISSN: | 1573-3270 | DOI: | 10.1007/s10484-022-09573-z | ISI #: | 000895581000001 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2023 |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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Ramakers et al, 2022, Applied Psychophysiol Biofeedback, accepted manuscript.pdf | Peer-reviewed author version | 928.07 kB | Adobe PDF | View/Open |
s10484-022-09573-z.pdf Restricted Access | Early view | 700.89 kB | Adobe PDF | View/Open Request a copy |
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