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http://hdl.handle.net/1942/39174
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DC Field | Value | Language |
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dc.contributor.author | Liu, Kang | - |
dc.contributor.author | Zhao, Hongda | - |
dc.contributor.author | Alvarez-Maestro, Mario | - |
dc.contributor.author | Gravas, Stavros | - |
dc.contributor.author | VAN RENTERGHEM, Koenraad | - |
dc.contributor.author | Zeng, Guohua | - |
dc.contributor.author | Ng, Chi-Fai | - |
dc.contributor.author | Laguna, Pilar | - |
dc.contributor.author | Teoh, Jeremy Yuen-Chun | - |
dc.contributor.author | De La Rosette, Jean | - |
dc.date.accessioned | 2023-01-09T08:16:08Z | - |
dc.date.available | 2023-01-09T08:16:08Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2023-01-05T12:01:30Z | - |
dc.identifier.citation | Current Oncology, 29 (12) , p. 9284 -9293 | - |
dc.identifier.uri | http://hdl.handle.net/1942/39174 | - |
dc.description.abstract | Objective: To evaluate the clinical outcomes of UTUC patients with or without concurrent bladder tumor. Design, Setting, and Participants: The Clinical Research Office of the Endourology Society-Urothelial Carcinomas of the Upper Tract (CROES-UTUC) Registry included 1134 UTUC patients with or without concurrent bladder tumor treated between 2014 and 2019. Results: In 218 (19.2%) cases, concurrent bladder tumor was present, while in 916 (80.8%) patients, no bladder cancer was found. In the multivariable Cox regression analysis, concomitant bladder tumor (hazard ratio (HR) 1.562, 95% confidence interval (CI) 0.954-2.560, p = 0.076) indicated a trend associated with recurrence-free survival for UTUC. Further data dissection confirmed that concomitant bladder tumor is a risk factor of bladder recurrence (HR 1.874, 95% CI 1.104-3.183, p = 0.020) but not UTUC recurrence (HR 0.876, 95% CI 0.292-2.625, p = 0.812). Kidney-sparing surgery (KSS) (HR 3.940, 95% CI 1.352-11.486, p = 0.012), pathological T staging >= pT2 (HR 2.840, 95% 1.039-7.763, p = 0.042) were significantly associated with UTUC recurrence. KSS does not affect bladder recurrence (HR 0.619, 95% CI 0.242-1.580, p = 0.315). A limitation is the retrospective nature of the present study analysis. Conclusions: The presence of concomitant bladder tumor does not increase risk of UTUC recurrence, but it results in an increased risk of bladder recurrence. KSS does not affect bladder recurrence and can still be considered in patients with concomitant bladder tumor. | - |
dc.description.sponsorship | This work is supported by an unrestricted educational grant from STORZ to the Clinical Research Office of the Endourology Society (CROES) | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.rights | 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). | - |
dc.subject.other | concomitant bladder tumor | - |
dc.subject.other | upper tract urothelial carcinoma | - |
dc.subject.other | kidney-sparing surgery | - |
dc.subject.other | recurrence-free survival | - |
dc.title | Concomitant Bladder Tumor Is a Risk Factor for Bladder Recurrence but Not Upper Tract | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 9293 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 9284 | - |
dc.identifier.volume | 29 | - |
local.format.pages | 10 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Teoh, JYC (corresponding author), Chinese Univ Hong Kong, SH Ho Urol Ctr, Dept Surg, Hong Kong 999077, Peoples R China. | - |
dc.description.notes | jeremyteoh@surgery.cuhk.edu.hk | - |
local.publisher.place | ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.3390/curroncol29120727 | - |
dc.identifier.pmid | 36547141 | - |
dc.identifier.isi | 000900604800001 | - |
dc.contributor.orcid | Teoh, Jeremy Yuen-Chun/0000-0002-9361-2342; Ng, | - |
dc.contributor.orcid | Chi-Fai/0000-0002-1723-9646 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Liu, Kang; Zhao, Hongda; Ng, Chi-Fai; Teoh, Jeremy Yuen-Chun] Chinese Univ Hong Kong, SH Ho Urol Ctr, Dept Surg, Hong Kong 999077, Peoples R China. | - |
local.description.affiliation | [Alvarez-Maestro, Mario] La Paz Univ Hosp, Dept Urol, Madrid 28001, Spain. | - |
local.description.affiliation | [Gravas, Stavros] Univ Thessaly, Fac Med, Sch Hlth Sci, Dept Urol, Larisa 41001, Greece. | - |
local.description.affiliation | [Van Renterghem, Koen] Jessa Hosp Univ Hasselt, Dept Urol, B-3500 Hasselt, Belgium. | - |
local.description.affiliation | [Zeng, Guohua] Guangzhou Med Univ, Dept Urol, Guangdong Key Lab Urol, Affiliated Hosp 1, Guangzhou 510000, Peoples R China. | - |
local.description.affiliation | [Laguna, Pilar; De La Rosette, Jean] Istanbul Medipol Univ, Medipol Mega Univ Hosp, Dept Urol, TR-34000 Istanbul, Turkey. | - |
local.uhasselt.international | yes | - |
item.accessRights | Open Access | - |
item.contributor | Liu, Kang | - |
item.contributor | Zhao, Hongda | - |
item.contributor | Alvarez-Maestro, Mario | - |
item.contributor | Gravas, Stavros | - |
item.contributor | VAN RENTERGHEM, Koenraad | - |
item.contributor | Zeng, Guohua | - |
item.contributor | Ng, Chi-Fai | - |
item.contributor | Laguna, Pilar | - |
item.contributor | Teoh, Jeremy Yuen-Chun | - |
item.contributor | De La Rosette, Jean | - |
item.fulltext | With Fulltext | - |
item.fullcitation | Liu, Kang; Zhao, Hongda; Alvarez-Maestro, Mario; Gravas, Stavros; VAN RENTERGHEM, Koenraad; Zeng, Guohua; Ng, Chi-Fai; Laguna, Pilar; Teoh, Jeremy Yuen-Chun & De La Rosette, Jean (2022) Concomitant Bladder Tumor Is a Risk Factor for Bladder Recurrence but Not Upper Tract. In: Current Oncology, 29 (12) , p. 9284 -9293. | - |
crisitem.journal.issn | 1198-0052 | - |
crisitem.journal.eissn | 1718-7729 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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Concomitant Bladder Tumor Is a Risk Factor for Bladder Recurrence but Not Upper Tract.pdf | Published version | 1.03 MB | Adobe PDF | View/Open |
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