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http://hdl.handle.net/1942/39549
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DC Field | Value | Language |
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dc.contributor.author | BIANCHI, Anna | - |
dc.contributor.author | Selva, Anna | - |
dc.contributor.author | RENIERS, Brigitte | - |
dc.contributor.author | Vanhavere, Filip | - |
dc.contributor.author | Conte, Valeria | - |
dc.date.accessioned | 2023-02-21T11:29:46Z | - |
dc.date.available | 2023-02-21T11:29:46Z | - |
dc.date.issued | 2023 | - |
dc.date.submitted | 2023-02-20T13:09:49Z | - |
dc.identifier.citation | PHYSICS IN MEDICINE AND BIOLOGY, 68 (3) (Art N° 034001) | - |
dc.identifier.uri | http://hdl.handle.net/1942/39549 | - |
dc.description.abstract | Objective. Microdosimetry offers a fast tool for radiation quality (RQ) verification to be implemented in treatment planning systems in proton therapy based on variable LET or RBE to move forward from the use of a fixed RBE of 1.1. It is known that the RBE of protons can increase up to 50% higher than that value in the last few millimetres of their range. Microdosimetry can be performed both experimentally and by means of Monte Carlo (MC) simulations. This paper has the aim of comparing the two approaches. Approach. Experimental measurements have been performed using a miniaturized Tissue equivalent proportional counter developed at the Legnaro National Laboratories of the Italian National Institute for Nuclear Physics with the aim of being used as RQ monitors for high intensity beams. MC simulations have been performed using the microdosimetric extension of TOPAS which provides optimized parameters and scorers for this application. Main results. Simulations were compared with experimental microdosimetric spectra in terms of shape of the spectra and their average values. Moreover, the latter have been investigated as possible estimators of LET obtained with the same MC code. The shape of the spectra is in general consistent with the experimental distributions and the average values of the distributions in both cases can predict the RQ increase with depth. Significance. This study aims at the comparison of microdosimetric spectra obtained from both experimental measurements and the microdosimetric extension of TOPAS in the same radiation field. | - |
dc.description.sponsorship | This work was supported by the 5th Scientific Commission of the Italian Institute for Nuclear Physics(INFN), the Belgian nuclear research Centre SCK•CEN and Hasselt University. This work has been partially supported by the ENEN + project that has received funding from the EURATOM research and training Work Programme 2016-2017-1 #755576. | - |
dc.language.iso | en | - |
dc.publisher | IOP Publishing Ltd | - |
dc.rights | 2023 Institute of Physics and Engineering in Medicine | - |
dc.subject.other | microdosimetry | - |
dc.subject.other | Monte Carlo simulations | - |
dc.subject.other | proton therapy | - |
dc.subject.other | TEPC | - |
dc.subject.other | Gas detectors | - |
dc.title | TOPAS simulations of the response of a mini-TEPC: benchmark with experimental data | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 3 | - |
dc.identifier.volume | 68 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Bianchi, A (corresponding author), INFN Lab Nazl Legnaro, viale Univ 2, I-35020 Legnaro, Italy. | - |
dc.description.notes | anna.bianchi@lnl.infn.it | - |
local.publisher.place | TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 034001 | - |
dc.identifier.doi | 10.1088/1361-6560/acabfe | - |
dc.identifier.pmid | 36595254 | - |
dc.identifier.isi | 000919200100001 | - |
dc.contributor.orcid | Conte, Valeria/0000-0002-4256-3827 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Bianchi, Anna; Selva, Anna; Conte, Valeria] INFN Lab Nazl Legnaro, viale Univ 2, I-35020 Legnaro, Italy. | - |
local.description.affiliation | [Reniers, Brigitte] UHasselt, Fac Engn Technol, Nucl Technol Ctr, Ctr Environm Sci, Agoralaan, B-3590 Diepenbeek, Belgium. | - |
local.description.affiliation | [Vanhavere, Filip] SCK CEN, Belgian Nucl Res Ctr, Boeretang 200, B-2400 Mol, Belgium. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.accessRights | Restricted Access | - |
item.fullcitation | BIANCHI, Anna; Selva, Anna; RENIERS, Brigitte; Vanhavere, Filip & Conte, Valeria (2023) TOPAS simulations of the response of a mini-TEPC: benchmark with experimental data. In: PHYSICS IN MEDICINE AND BIOLOGY, 68 (3) (Art N° 034001). | - |
item.contributor | BIANCHI, Anna | - |
item.contributor | Selva, Anna | - |
item.contributor | RENIERS, Brigitte | - |
item.contributor | Vanhavere, Filip | - |
item.contributor | Conte, Valeria | - |
crisitem.journal.issn | 0031-9155 | - |
crisitem.journal.eissn | 1361-6560 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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TOPAS simulations of the response of a mini-TEPC_ benchmark with experimental data.pdf Restricted Access | Published version | 1.01 MB | Adobe PDF | View/Open Request a copy |
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