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DC Field | Value | Language |
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dc.contributor.author | FIEUWS, Steffen | - |
dc.contributor.author | VERBEKE, Geert | - |
dc.contributor.author | MOLENBERGHS, Geert | - |
dc.date.accessioned | 2007-12-07T14:08:51Z | - |
dc.date.available | 2007-12-07T14:08:51Z | - |
dc.date.issued | 2007 | - |
dc.identifier.citation | STATISTICAL METHODS IN MEDICAL RESEARCH, 16(5). p. 387-397 | - |
dc.identifier.issn | 0962-2802 | - |
dc.identifier.uri | http://hdl.handle.net/1942/4011 | - |
dc.description.abstract | Mixed models are widely used for the analysis of one repeatedly measured outcome. If more than one outcome is present, a mixed model can be used for each one. These separate models can be tied together into a multivariate mixed model by specifying a joint distribution for their random effects. This strategy has been used for joining multivariate longitudinal profiles or other types of multivariate repeated data. However, computational problems are likely to occur when the number of outcomes increases. A pairwise modeling approach, in which all possible bivariate mixed models are fitted and where inference follows from pseudo-likelihood arguments, has been proposed to circumvent the dimensional limitations in multivariate mixed models. An analysis on 22-variate longitudinal measurements of hearing thresholds illustrates the performance of the pairwise approach in the context of multivariate linear mixed models. For generalized linear mixed models, a data set containing repeated measurements of seven aspects of psycho-cognitive functioning will be analyzed. | - |
dc.description.sponsorship | The authors acknowledge support from the Interuniversity Attraction Poles Program P5/24 – Belgian State – Federal Office for Scientific, Technical and Cultural Affairs. | - |
dc.language.iso | en | - |
dc.publisher | SAGE PUBLICATIONS LTD | - |
dc.rights | © 2007 SAGE Publications | - |
dc.title | Random-effects models for multivariate repeated measures | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 397 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 387 | - |
dc.identifier.volume | 16 | - |
local.format.pages | 11 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Katholieke Univ Leuven, Ctr Biostat, UZ St Rafael, B-3000 Louvain, Belgium. Hasselt Univ, Ctr Stat, Diepenbeek, Belgium.VERBEKE, G, Katholieke Univ Leuven, Ctr Biostat, UZ St Rafael, Kapucijnenvoer 35, B-3000 Louvain, Belgium.geert.verbeke@med.kuleuven.be | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.bibliographicCitation.oldjcat | A1 | - |
dc.identifier.doi | 10.1177/0962280206075305 | - |
dc.identifier.isi | 000250441300002 | - |
dc.identifier.url | https://www.researchgate.net/publication/6183286_Random-effects_model_for_multivariate_repeated_measures | - |
item.fullcitation | FIEUWS, Steffen; VERBEKE, Geert & MOLENBERGHS, Geert (2007) Random-effects models for multivariate repeated measures. In: STATISTICAL METHODS IN MEDICAL RESEARCH, 16(5). p. 387-397. | - |
item.validation | ecoom 2008 | - |
item.contributor | FIEUWS, Steffen | - |
item.contributor | VERBEKE, Geert | - |
item.contributor | MOLENBERGHS, Geert | - |
item.fulltext | With Fulltext | - |
item.accessRights | Restricted Access | - |
crisitem.journal.issn | 0962-2802 | - |
crisitem.journal.eissn | 1477-0334 | - |
Appears in Collections: | Research publications |
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0962280206075305.pdf Restricted Access | Published version | 380.16 kB | Adobe PDF | View/Open Request a copy |
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