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http://hdl.handle.net/1942/40177
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DC Field | Value | Language |
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dc.contributor.author | Garcia-Carro, Clara | - |
dc.contributor.author | Jhaveri, Kenar D. | - |
dc.contributor.author | SPRANGERS, Ben | - |
dc.date.accessioned | 2023-05-25T06:30:45Z | - |
dc.date.available | 2023-05-25T06:30:45Z | - |
dc.date.issued | 2023 | - |
dc.date.submitted | 2023-05-23T09:17:38Z | - |
dc.identifier.citation | Clinical Kidney Journal, 16 (5) , p. 773 -775 | - |
dc.identifier.uri | http://hdl.handle.net/1942/40177 | - |
dc.description.abstract | In the last decade, immune checkpoint inhibitors (ICI) have become a cornerstone in the treatment of a wide range of malignancies. It is well established that ICI are associated with multiple immune-related adverse events, a spectrum of autoimmune toxicities, that can also affect the kidney. In this issue of Clinical Kidney Journal, Kanbay et al. report the first meta-analysis and systematic review evaluating the impact of ICI-related acute kidney injury (ICI-AKI) on long-term kidney and patient outcomes (including mortality). The authors report a high incidence of ICI-AKI (mostly mild AKI episodes) with high rates of recovery resulting in a good kidney outcomes. However, the occurrence of ICI-AKI has a significant impact on mortality in ICI-treated patients probably related to temporary or definitive cessation of ICI. Additional studies are needed to establish the safety of ICI re-challenging in patients with ICI-AKI, and to determine the optimal treatment strategy for them. | - |
dc.language.iso | en | - |
dc.publisher | OXFORD UNIV PRESS | - |
dc.rights | The Author(s) 2023. Published by Oxford University Press on behalf of the ERA. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com | - |
dc.subject.other | acute kidney injury | - |
dc.subject.other | immune checkpoint inhibitors | - |
dc.subject.other | immune-related adverse events | - |
dc.subject.other | mortality | - |
dc.subject.other | onconephrology | - |
dc.title | Revisiting the role of acute kidney injury in patients on immune checkpoint inhibitors: a good prognosis renal event with a significant impact on survival | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 775 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 773 | - |
dc.identifier.volume | 16 | - |
local.format.pages | 3 | - |
local.bibliographicCitation.jcat | A2 | - |
dc.description.notes | Sprangers, B (corresponding author), Ziekenhuis Oost Limburg, Dept Med, Div Nephrol, Genk, Belgium.; Sprangers, B (corresponding author), Biomed Res Inst, Dept Immunol & Infect, Diepenbeek, Belgium. | - |
dc.description.notes | ben.sprangers@zol.be | - |
local.publisher.place | GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Editorial Material | - |
dc.identifier.doi | 10.1093/ckj/sfad035 | - |
dc.identifier.pmid | 37151419 | - |
dc.identifier.isi | 000979293500001 | - |
dc.contributor.orcid | Jhaveri, Kenar D/0000-0003-1578-0524 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Garcia-Carro, Clara] San Carlos Clin Univ Hosp, Nephrol Dept, Madrid, Spain. | - |
local.description.affiliation | [Jhaveri, Kenar D.] Donald & Barbara Zucker Sch Med Hofstra Northwell, Div Kidney Dis & Hypertens, Dept Med, Great Neck, NY USA. | - |
local.description.affiliation | [Sprangers, Ben] Ziekenhuis Oost Limburg, Dept Med, Div Nephrol, Genk, Belgium. | - |
local.description.affiliation | [Sprangers, Ben] Biomed Res Inst, Dept Immunol & Infect, Diepenbeek, Belgium. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.fullcitation | Garcia-Carro, Clara; Jhaveri, Kenar D. & SPRANGERS, Ben (2023) Revisiting the role of acute kidney injury in patients on immune checkpoint inhibitors: a good prognosis renal event with a significant impact on survival. In: Clinical Kidney Journal, 16 (5) , p. 773 -775. | - |
item.accessRights | Open Access | - |
item.contributor | Garcia-Carro, Clara | - |
item.contributor | Jhaveri, Kenar D. | - |
item.contributor | SPRANGERS, Ben | - |
crisitem.journal.issn | 2048-8505 | - |
crisitem.journal.eissn | 2048-8513 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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Revisiting the role of acute kidney injury in patients on immune checkpoint inhibitors_ a good prognosis renal event with a significant impact on survival.pdf | Published version | 187.6 kB | Adobe PDF | View/Open |
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