A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease

Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/40233

Title:	A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease
Authors:	Dagorn, Pascale Gluais Buchholz, Bjoern Kraus, Andre Batchuluun, Battsetseg Bange, Hester BLOCKKEN, Laura Steinberg, Gregory R. Moller, David E. Hallakou-Bozec, Sophie
Issue Date:	2023
Publisher:	ELSEVIER SCIENCE INC
Source:	KIDNEY INTERNATIONAL, 103 (5) , p. 917 -929
Abstract:	A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease
Notes:	Hallakou-Bozec, S (corresponding author), Poxel SA, 259 Av Jean Jaures, F-69007 Lyon, France. sophie.bozec@poxelpharma.com
Keywords:	ADPKD;AMPK;PXL770;fibrosis;inflammation;mitochondria;Mice;Animals;Dogs;Adenosine Monophosphate;AMP-Activated Protein Kinases;Kidney;Mice, Knockout;Disease Progression;TRPP Cation Channels;Polycystic Kidney, Autosomal Dominant;Renal Insufficiency;Cysts
Document URI:	http://hdl.handle.net/1942/40233
ISSN:	0085-2538
e-ISSN:	1523-1755
DOI:	10.1016/j.kint.2023.01.026
ISI #:	000984794600001
Rights:	2023, International Society of Nephrology. Published by Elsevier Inc. This is an open access article under the CC BY license (http:// creativecommons.org/licenses/by/4.0/).
Category:	A1
Type:	Journal Contribution
Appears in Collections:	Research publications

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