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http://hdl.handle.net/1942/40233| Title: | A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease | Authors: | Dagorn, Pascale Gluais Buchholz, Bjoern Kraus, Andre Batchuluun, Battsetseg Bange, Hester BLOCKKEN, Laura Steinberg, Gregory R. Moller, David E. Hallakou-Bozec, Sophie |
Issue Date: | 2023 | Publisher: | ELSEVIER SCIENCE INC | Source: | KIDNEY INTERNATIONAL, 103 (5) , p. 917 -929 | Abstract: | A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease | Notes: | Hallakou-Bozec, S (corresponding author), Poxel SA, 259 Av Jean Jaures, F-69007 Lyon, France. sophie.bozec@poxelpharma.com |
Keywords: | ADPKD;AMPK;PXL770;fibrosis;inflammation;mitochondria;Mice;Animals;Dogs;Adenosine Monophosphate;AMP-Activated Protein Kinases;Kidney;Mice, Knockout;Disease Progression;TRPP Cation Channels;Polycystic Kidney, Autosomal Dominant;Renal Insufficiency;Cysts | Document URI: | http://hdl.handle.net/1942/40233 | ISSN: | 0085-2538 | e-ISSN: | 1523-1755 | DOI: | 10.1016/j.kint.2023.01.026 | ISI #: | 000984794600001 | Rights: | 2023, International Society of Nephrology. Published by Elsevier Inc. This is an open access article under the CC BY license (http:// creativecommons.org/licenses/by/4.0/). | Category: | A1 | Type: | Journal Contribution |
| Appears in Collections: | Research publications |
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| A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease.pdf | Published version | 2.65 MB | Adobe PDF | View/Open |
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