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http://hdl.handle.net/1942/40344
Title: | Single versus multiple dose ivermectin regimen in onchocerciasis-infected persons with epilepsy treated with phenobarbital: a randomized clinical trial in the Democratic Republic of Congo | Data Creator - person: | Mandro, Michel Siewe Fodjo, Joseph Nelson Dusabimana, Alfred Mukendi, Deby HAESENDONCKX, Steven Lokonda, Richard Nakato, Swabra Nyisi, Francoise Abhafule, Germain Wonya'Rossi, D Hotterbeekx, An ABRAMS, Steven Colebunders, Robert |
Data Creator - organization: | University of Antwerp Hasselt University University of Kinshasa Centre de Recherche en Maladies Tropicales de l’Ituri Provincial Health Division Ituri, Ministry of Health Programme National de Lutte contre l’Onchocercose |
Data Curator - person: | Mandro, Michel | Data Curator - organization: | University of Antwerp | Rights Holder - person: | Mandro, Michel | Rights Holder - organization: | University of Antwerp | Publisher: | Zenodo | Issue Date: | 2019 | Abstract: | Open data for a randomized clinical trial performed in onchocerciasis-endemic villages of the Logo health zone in Ituri province in the Democratic Republic of Congo where mass ivermectin administration had never been implemented. Ivermectin naïve, persons with epilepsy with Onchocerca volvulus infection were randomly allocated to receive ivermectin once, twice or thrice over a one year period of follow up. At the same time they were treated with the anti-epileptic drug phenobarbital. At baseline, information was collected on seizure semiology, seizure frequency, epilepsy risk factors, relevant medical history, previous AED and ivermectin use. The primary outcome was seizure freedom during the last four months of the 12-month follow up period. | Research Discipline: | Medical and health sciences > Clinical sciences > Tropical medicine > Tropical medicine (03023501) | Keywords: | Ivermectin;onchocerciasis;epilepsy;Democratic Republic of Congo;Onchocerca volvulus;seizure | DOI: | 10.5281/zenodo.3564280 | Link to publication/dataset: | https://zenodo.org/record/3564280 | Source: | Zenodo. 10.5281/zenodo.3564280 https://zenodo.org/record/3564280 | Publications related to the dataset: | 10.3390/pathogens9030205 | License: | Creative Commons Attribution 4.0 International (CC-BY-4.0) | Access Rights: | Open Access | Version: | 1.0 | Category: | DS | Type: | Dataset |
Appears in Collections: | Datasets |
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