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Title: | Testing the functional reserve of the kidney before hematopoietic stem cell transplantation: doubt remains | Authors: | DE MOOR, Bart SPRANGERS, Ben |
Issue Date: | 2023 | Publisher: | OXFORD UNIV PRESS | Source: | Clinical Kidney Journal, 16 (6) , p. 905 -908 | Abstract: | Acute kidney injury is a common and important complication following hematopoietic stem cell transplantation. In the nephrology community, acute kidney injury is no longer viewed as a simple temporary and potentially reversible decline in kidney clearance as acute kidney injury imposes a risk for immediate and future complications. Therefore, stratifying patients for the risk of acute kidney injury following stem cell transplantation would be very helpful to optimize peri-stem cell transplant management and could potentially improve outcomes in this patient population. In the current issue of CKJ, Mancianti et al. report on the testing of the kidney's functional reserve in patients planned for stem cell transplantation and demonstrate that stem cell transplant candidates with a preserved kidney response on a protein load had a higher chance of full kidney recovery after an episode of acute kidney injury. In this editorial, we discuss the kidney's functional reserve test and its limitations. | Notes: | De Moor, B (corresponding author), Jessa Ziekenhuis, Dept Nephrol, Hasselt, Belgium.; De Moor, B (corresponding author), UHasselt, Biomed Res Inst, Dept Immunol & Infect, Diepenbeek, Belgium. bart.demoor@jesssazh.be |
Keywords: | acute kidney injury;hematopoietic stem cell transplantation;kidney function test | Document URI: | http://hdl.handle.net/1942/40368 | ISSN: | 2048-8505 | e-ISSN: | 2048-8513 | DOI: | 10.1093/ckj/sfad078 | ISI #: | 000992594900001 | Rights: | The Author(s) 2023. Published by Oxford University Press on behalf of the ERA. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com | Category: | A2 | Type: | Journal Contribution |
Appears in Collections: | Research publications |
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Testing the functional reserve of the kidney before hematopoietic stem cell transplantation_ doubt remains.pdf | Published version | 1.08 MB | Adobe PDF | View/Open |
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