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http://hdl.handle.net/1942/40414
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DC Field | Value | Language |
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dc.contributor.author | Schallmoser, A | - |
dc.contributor.author | Bakjaji, F | - |
dc.contributor.author | Konigsberger, S | - |
dc.contributor.author | John, J | - |
dc.contributor.author | Farber, C | - |
dc.contributor.author | Schmidt, E | - |
dc.contributor.author | Breitenbach-Koller, H | - |
dc.contributor.author | Allam, JP | - |
dc.contributor.author | VERGUTS, Jasper | - |
dc.contributor.author | Sanger, N | - |
dc.date.accessioned | 2023-06-15T11:22:40Z | - |
dc.date.available | 2023-06-15T11:22:40Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2023-06-13T07:20:35Z | - |
dc.identifier.citation | Translational Andrology and Urology, 10 (1) , p. 448 -454 | - |
dc.identifier.uri | http://hdl.handle.net/1942/40414 | - |
dc.description.abstract | Background: Highly viscous semen reduces sperm motility significantly and can contribute to infertility. When processing semen samples, few techniques exist to induce liquefaction in case of seminal hyperviscosity such as different washing steps and mechanical treatment. The use of alpha-chymotrypsin seems controversial due to possible negative effects on fertilisation rates after in vitro fertilization (IVF). The main objective of this study was to examine the influence of mild alpha-chymotrypsin treatment of semen samples on the fertilisation rate after artificial reproductive treatment (ART).Methods: The fertilization rate of 52 ART cycles was examined following IVF using a low dose of alpha-chymotrypsin to induce liquefaction of highly viscous semen and was compared to a control group of 88 ART cycles.Results: There was no significant difference in the fertilization rates of alpha-chymotrypsin treated semen samples compared to the control group; pregnancy rates were unaffected.Conclusions: The use of mild alpha-chymotrypsin treatment of semen samples in case of hyperviscosity does not appear to impact negatively on the fertilization rates after ART and could be regarded as an additional method to induce liquefaction of highly viscous semen samples in IVF. | - |
dc.language.iso | en | - |
dc.publisher | AME PUBL CO | - |
dc.subject.other | Semen | - |
dc.subject.other | chymotrypsin | - |
dc.subject.other | viscosity | - |
dc.title | Effect of mild alpha-chymotrypsin treatment of highly viscous semen samples on fertilization rates | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 454 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 448 | - |
dc.identifier.volume | 10 | - |
local.bibliographicCitation.jcat | A1 | - |
local.publisher.place | FLAT-RM C 16F, KINGS WING PLAZA 1, NO 3 KWAN ST, SHATIN, HONG KONG 00000, PEOPLES R CHINA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.21037/tau-20-1013 | - |
dc.identifier.isi | 000608976700010 | - |
local.provider.type | Web of Science | - |
local.uhasselt.international | yes | - |
item.fullcitation | Schallmoser, A; Bakjaji, F; Konigsberger, S; John, J; Farber, C; Schmidt, E; Breitenbach-Koller, H; Allam, JP; VERGUTS, Jasper & Sanger, N (2021) Effect of mild alpha-chymotrypsin treatment of highly viscous semen samples on fertilization rates. In: Translational Andrology and Urology, 10 (1) , p. 448 -454. | - |
item.contributor | Schallmoser, A | - |
item.contributor | Bakjaji, F | - |
item.contributor | Konigsberger, S | - |
item.contributor | John, J | - |
item.contributor | Farber, C | - |
item.contributor | Schmidt, E | - |
item.contributor | Breitenbach-Koller, H | - |
item.contributor | Allam, JP | - |
item.contributor | VERGUTS, Jasper | - |
item.contributor | Sanger, N | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
crisitem.journal.issn | 2223-4683 | - |
crisitem.journal.eissn | 2223-4691 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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58891-PB5-6470-R2.pdf | Published version | 265.9 kB | Adobe PDF | View/Open |
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