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http://hdl.handle.net/1942/40443
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DC Field | Value | Language |
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dc.contributor.author | Galloo, Xavier | - |
dc.contributor.author | Meucci, Maria Chiara | - |
dc.contributor.author | STASSEN, Jan | - |
dc.contributor.author | Dietz, Marlieke F. | - |
dc.contributor.author | Prihadi, Edgard A. | - |
dc.contributor.author | van der Bijl, Pieter | - |
dc.contributor.author | Marsan, Nina Ajmone | - |
dc.contributor.author | Braun, Jerry | - |
dc.contributor.author | Bax, Jeroen J. | - |
dc.contributor.author | Delgado, Victoria | - |
dc.date.accessioned | 2023-06-20T07:03:56Z | - |
dc.date.available | 2023-06-20T07:03:56Z | - |
dc.date.issued | 2023 | - |
dc.date.submitted | 2023-06-16T09:50:10Z | - |
dc.identifier.citation | STRUCTURAL HEART-THE JOURNAL OF THE HEART TEAM, 7 (1) (Art N° 100101) | - |
dc.identifier.uri | http://hdl.handle.net/1942/40443 | - |
dc.description.abstract | Background: Changes in right ventricular (RV) dimensions and function after tricuspid valve (TV) surgery and their association with long-term outcomes remain largely unexplored. The current study evaluated RV reverse remodeling, based on changes in RV dimensions and function, after TV surgery for significant (moderate or severe) tricuspid regurgitation (TR) and their association with outcome.Methods: A total of 121 patients (mean age 63 +/- 12 years, 47% males) with significant TR treated with TV surgery were included in this analysis. The population was stratified by tertiles of percentage reduction of RV end-systolic area (RVESA) and absolute change of RV fractional area change (RVFAC). Five-year mortality rates were compared across the tertiles of RV remodeling and independent associates of mortality were investigated.Results: Tertile 3 consisted of patients presenting with a reduction in RVESA >= 17.2% and an improvement in RVFAC >= 2.3% after TV surgery. Cumulative survival rates were significantly better in patients within tertile 3 of RVESA reduction: 90% vs. 49% for tertile 1 and 69% for tertile 2 (log-rank p = 0.002) and within tertile 3 of RVFAC improvement: 87% vs. 57% for tertile 1 and 65% for tertile 2 (log-rank p = 0.02). Tertiles 3 of RVESA reduction and RVFAC improvement were both independently associated with better survival after TV surgery compared to tertiles 1 (hazard ratio: 0.221 [95% CI: 0.074-0.658] and 0.327 [95% CI: 0.118-0.907], respectively).Conclusions: The extent of RV reverse remodeling, based on reduction in RVESA and improvement in RVFAC, was associated with better survival at 5-year follow-up of TV surgery for significant TR. | - |
dc.description.sponsorship | The Department of Cardiology, Heart Lung Center, Leiden University Medical Centre has received research grants from Abbott Vascular, Bayer, Biotronik, Bioventrix, Boston Scientific, Edwards Lifesciences, GE Healthcare, Ionis, Medtronic, and Novartis. J.S. received funding from the European Society of Cardiology (ESC Training Grant App000064741). N.A.M. received speaker fees from Abbott Vascular and GE Healthcare. J.J.B. received speaker fees from Abbott Vascular and Edwards Lifesciences. V.D. received speaker fees from Abbott Vascular, Edwards Lifesciences, GE Healthcare, Medtronic, MSD, and Novartis. The other authors had no conflicts to declare. | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.rights | 2022 The Author(s). Published by Elsevier Inc. on behalf of Cardiovascular Research Foundation. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | - |
dc.subject.other | Prognosis | - |
dc.subject.other | Right ventricular remodeling | - |
dc.subject.other | Tricuspid regurgitation | - |
dc.subject.other | Tricuspid valve surgery | - |
dc.title | Right Ventricular Reverse Remodeling After Tricuspid Valve Surgery for Significant Tricuspid Regurgitation | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 1 | - |
dc.identifier.volume | 7 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Delgado, V (corresponding author), Leiden Univ, Dept Cardiol, Med Ctr, Albinusdreef 2, NL-2330 RC Leiden, Netherlands. | - |
dc.description.notes | v.delgado@lumc.nl | - |
local.publisher.place | STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 100101 | - |
dc.identifier.doi | 10.1016/j.shj.2022.100101 | - |
dc.identifier.pmid | 37275311 | - |
dc.identifier.isi | 000996308200001 | - |
dc.contributor.orcid | Bax, Jeroen/0000-0001-7368-0500; delgado, victoria/0000-0002-9841-2737; | - |
dc.contributor.orcid | Braun, Jerry/0000-0002-4504-6235 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Galloo, Xavier; Meucci, Maria Chiara; Stassen, Jan; Dietz, Marlieke F.; Prihadi, Edgard A.; van der Bijl, Pieter; Marsan, Nina Ajmone; Bax, Jeroen J.; Delgado, Victoria] Leiden Univ, Dept Cardiol, Med Ctr, Leiden, Netherlands. | - |
local.description.affiliation | [Galloo, Xavier] Vrije Univ Brussel VUB, Univ Ziekenhuis Brussel UZ Brussel, Dept Cardiol, Brussels, Belgium. | - |
local.description.affiliation | [Meucci, Maria Chiara] Univ Cattolica Sacro Cuore, Dept Cardiovasc & Thorac Sci, Rome, Italy. | - |
local.description.affiliation | [Stassen, Jan] Jessa Hosp, Dept Cardiol, Hasselt, Belgium. | - |
local.description.affiliation | [Prihadi, Edgard A.] Ziekenhuis Netwerk Antwerpen ZNA Middelheim, Hartcentrum, Antwerp, Belgium. | - |
local.description.affiliation | [Braun, Jerry] Leiden Univ, Dept Cardiothorac Surg, Med Ctr, Leiden, Netherlands. | - |
local.description.affiliation | [Bax, Jeroen J.] Univ Turku, Turku Univ Hosp, Heart Ctr, Turku, Finland. | - |
local.description.affiliation | [Delgado, Victoria] Leiden Univ, Dept Cardiol, Med Ctr, Albinusdreef 2, NL-2330 RC Leiden, Netherlands. | - |
local.uhasselt.international | yes | - |
item.fullcitation | Galloo, Xavier; Meucci, Maria Chiara; STASSEN, Jan; Dietz, Marlieke F.; Prihadi, Edgard A.; van der Bijl, Pieter; Marsan, Nina Ajmone; Braun, Jerry; Bax, Jeroen J. & Delgado, Victoria (2023) Right Ventricular Reverse Remodeling After Tricuspid Valve Surgery for Significant Tricuspid Regurgitation. In: STRUCTURAL HEART-THE JOURNAL OF THE HEART TEAM, 7 (1) (Art N° 100101). | - |
item.fulltext | With Fulltext | - |
item.contributor | Galloo, Xavier | - |
item.contributor | Meucci, Maria Chiara | - |
item.contributor | STASSEN, Jan | - |
item.contributor | Dietz, Marlieke F. | - |
item.contributor | Prihadi, Edgard A. | - |
item.contributor | van der Bijl, Pieter | - |
item.contributor | Marsan, Nina Ajmone | - |
item.contributor | Braun, Jerry | - |
item.contributor | Bax, Jeroen J. | - |
item.contributor | Delgado, Victoria | - |
item.accessRights | Open Access | - |
crisitem.journal.issn | 2474-8706 | - |
crisitem.journal.eissn | 2474-8714 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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Right Ventricular Reverse Remodeling After Tricuspid Valve Surgery for Significant Tricuspid Regurgitation.pdf | Published version | 1.22 MB | Adobe PDF | View/Open |
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