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Title: | Acute heart failure and valvular heart disease: A scientific statement of the Heart Failure Association, the Association for Acute CardioVascular Care and the European Association of Percutaneous Cardiovascular Interventions of the European Society of Cardiology | Authors: | Chioncel, Ovidiu Adamo, Marianna Nikolaou, Maria Parissis, John Mebazaa, Alexandre Yilmaz, Mehmet Birhan Hassager, Christian Moura, Brenda Bauersachs, Johann Harjola, Veli-Pekka Antohi, Elena-Laura Ben-Gal, Tuvia Collins, Sean P. Iliescu, Vlad Anton Abdelhamid, Magdy Celutkiene, Jelena Adamopoulos, Stamatis Lund, Lars H. Cicoira, Mariantonietta Masip, Josep Skouri, Hadi Gustafsson, Finn Rakisheva, Amina Ahrens, Ingo Mortara, Andrea Janowska, Ewa A. Almaghraby, Abdallah Damman, Kevin Miro, Oscar Huber, Kurt Ristic, Arsen Hill, Loreena MULLENS, Wilfried Chieffo, Alaide Bartunek, Jozef Paolisso, Pasquale Bayes-Genis, Antoni Anker, Stefan D. Price, Susanna Filippatos, Gerasimos Ruschitzka, Frank Seferovic, Petar Vidal-Perez, Rafael Vahanian, Alec Metra, Marco McDonagh, Theresa A. Barbato, Emanuele Coats, Andrew J. S. Rosano, Giuseppe M. C. |
Issue Date: | 2023 | Publisher: | WILEY | Source: | EUROPEAN JOURNAL OF HEART FAILURE, 25 (7) , p. 1025-1048 | Abstract: | Acute heart failure (AHF) represents a broad spectrum of disease states, resulting from the interaction between an acute precipitant and a patient's underlying cardiac substrate and comorbidities. Valvular heart disease (VHD) is frequently associated with AHF. AHF may result from several precipitants that add an acute haemodynamic stress superimposed on a chronic valvular lesion or may occur as a consequence of a new significant valvular lesion. Regardless of the mechanism, clinical presentation may vary from acute decompensated heart failure to cardiogenic shock. Assessing the severity of VHD as well as the correlation between VHD severity and symptoms may be difficult in patients with AHF because of the rapid variation in loading conditions, concomitant destabilization of the associated comorbidities and the presence of combined valvular lesions. Evidence-based interventions targeting VHD in settings of AHF have yet to be identified, as patients with severe VHD are often excluded from randomized trials in AHF, so results from these trials do not generalize to those with VHD. Furthermore, there are not rigorously conducted randomized controlled trials in the setting of VHD and AHF, most of the data coming from observational studies. Thus, distinct to chronic settings, current guidelines are very elusive when patients with severe VHD present with AHF, and a clear-cut strategy could not be yet defined. Given the paucity of evidence in this subset of AHF patients, the aim of this scientific statement is to describe the epidemiology, pathophysiology, and overall treatment approach for patients with VHD who present with AHF. [GRAPHICS] | Notes: | Chioncel, O (corresponding author), Emergency Inst Cardiovasc Dis Prof CC Iliescu, Bucharest, Romania.; Chioncel, O (corresponding author), Univ Med & Pharm Carol Davila, Fundeni 258, Bucharest 072435, Romania.; Adamo, M (corresponding author), Univ Brescia, Dept Med & Surg Specialties Radiol Sci & Publ Hlth, Cardiol, Piazza Mercato 15, I-25121 Brescia, Italy. ochioncel@yahoo.co.uk; mariannaadamo@hotmail.com |
Keywords: | Acute heart failure;Management;Valvular heart disease | Document URI: | http://hdl.handle.net/1942/40544 | ISSN: | 1388-9842 | e-ISSN: | 1879-0844 | DOI: | 10.1002/ejhf.2918 | ISI #: | 001008670300001 | Rights: | 2023 European Society of Cardiology. Free access | Category: | A1 | Type: | Journal Contribution |
Appears in Collections: | Research publications |
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European J of Heart Fail - 2023 - Chioncel.pdf | Published version | 1.99 MB | Adobe PDF | View/Open |
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