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http://hdl.handle.net/1942/40688
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DC Field | Value | Language |
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dc.contributor.author | Dams, Lore | - |
dc.contributor.author | Van der Gucht, Elien | - |
dc.contributor.author | Devoogdt, Nele | - |
dc.contributor.author | Smeets, Ann | - |
dc.contributor.author | Bernar, Koen | - |
dc.contributor.author | Morlion, Bart | - |
dc.contributor.author | Godderis, Lode | - |
dc.contributor.author | Haenen, Vincent | - |
dc.contributor.author | De Vrieze, Tessa | - |
dc.contributor.author | FIEUWS, Steffen | - |
dc.contributor.author | Moloney, Niamh | - |
dc.contributor.author | Van Wilgen, Paul | - |
dc.contributor.author | Meeus , Mira | - |
dc.contributor.author | De Groef, An | - |
dc.date.accessioned | 2023-08-21T07:51:26Z | - |
dc.date.available | 2023-08-21T07:51:26Z | - |
dc.date.issued | 2023 | - |
dc.date.submitted | 2023-08-03T09:57:32Z | - |
dc.identifier.citation | PAIN, 164 (7) , p. 1489 -1501 | - |
dc.identifier.issn | 0304-3959 | - |
dc.identifier.issn | 1872-6623 | - |
dc.identifier.uri | http://hdl.handle.net/1942/40688 | - |
dc.description.abstract | Pain is one of the most common and long-lasting side effects reported by women surgically treated for breast cancer. Educational interventions may optimize the current physical therapy modalities for pain prevention or relief in this population. Pain neuroscience education (PNE) is an educational intervention that explains the pain experience not only from a biomedical perspective but also the psychological and social factors that contribute to it. Through a double-blinded randomized controlled trial (EduCan trial) it was investigated if PNE, in addition to the standard physiotherapy program immediately after breast cancer surgery, was more effective over the course of 18 months postoperatively than providing a biomedical explanation for pain. Primary outcome was the change in pain-related disability (Pain Disability Index, 0-70) over 12 months. Secondary outcomes included change in pain intensity, upper limb function, physical activity level, and emotional functioning over 4, 6, 8, 12, and 18 months postoperatively. Multivariate linear models for repeated (longitudinal) measures were used to compare changes. Preoperative and postoperative moderators of the change in pain-related disability were also explored. Of 184 participants randomized, the mean (SD) age in the PNE and biomedical education group was 55.4 (11.5) and 55.2 (11.4) years, respectively. The change in pain-related disability from baseline to 12 months postoperatively did not differ between the 2 groups (PNE 4.22 [95% confidence interval [CI]: 1.40-7.03], biomedical 5.53 [95% CI: 2.74-8.32], difference in change -1.31 [95% CI: -5.28 to 2.65], P = 0.516). Similar results were observed for all secondary outcomes. Future research should explore whether a more patient-tailored intervention would yield better results. | - |
dc.description.sponsorship | The study is funded by Research Foundations—Flanders (FWO) (T005117N). The authors thank Frauke Penen for treating the patients. We are grateful to the nurses of the surgical oncology department and the medical staff of the multidisciplinary breast clinic for encouraging patients to participate in our study. Finally, we would like to thank all of the patients who participated in this study. Support statement: A. De Groef and T. De Vrieze are postdoctoral research fellows of the FWO-Flanders. | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.rights | 2023 International Association for the Study of Pain | - |
dc.subject.other | Breast cancer | - |
dc.subject.other | Randomized controlled trial | - |
dc.subject.other | Pain neuroscience education | - |
dc.subject.other | Biopsychosocial | - |
dc.subject.other | Pain-related disability | - |
dc.title | Effect of pain neuroscience education after breast cancer surgery on pain, physical, and emotional functioning: a double-blinded randomized controlled trial (EduCan trial) | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1501 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 1489 | - |
dc.identifier.volume | 164 | - |
local.format.pages | 13 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Dams, L (corresponding author), Univ Antwerp, Dept Rehabil Sci & Physiotherapy, Campus Drie Eiken Univ Pl 1,R315, B-2610 Antwerp, Belgium. | - |
dc.description.notes | lore.dams@uantwerpen.be; elienvandergucht@gmail.com; | - |
dc.description.notes | nele.devoogdt@kuleuven.be; ann.smeets@uzleuven.be; | - |
dc.description.notes | koen.bernar@uzleuven.be; bart.morlion@uzleuven.be; | - |
dc.description.notes | lode.godderis@kuleuven.be; vincent.haenen@kuleuven.be; | - |
dc.description.notes | tessa.devrieze@kuleuven.be; steffen.fieuws@kuleuven.be; | - |
dc.description.notes | niamh.moloney@mq.edu.au; p.vanwilgen@transcare.nl; | - |
dc.description.notes | mira.meeus@uantwerpen.be; an.degroef@kuleuven.be | - |
local.publisher.place | TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1097/j.pain.0000000000002838 | - |
dc.identifier.pmid | 36637138 | - |
dc.identifier.isi | 001011949500008 | - |
dc.contributor.orcid | Meeus, Mira/0000-0002-2022-5114; Godderis, Lode/0000-0003-4764-8835; De | - |
dc.contributor.orcid | Groef, An/0000-0001-6771-2836; De Vrieze, Tessa/0000-0002-5719-6169; | - |
dc.contributor.orcid | Dams, Lore/0000-0002-1283-6185; Haenen, Vincent/0000-0001-7056-6286; Van | - |
dc.contributor.orcid | der Gucht, Elien/0000-0002-9778-1143 | - |
dc.identifier.eissn | 1872-6623 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Dams, Lore; Van der Gucht, Elien; Haenen, Vincent; Meeus, Mira; De Groef, An] Univ Antwerp, Fac Med & Hlth Sci, Dept Rehabil Sci & Physiotherapy, MOVANT, Antwerp, Belgium. | - |
local.description.affiliation | [Dams, Lore; Van der Gucht, Elien; Devoogdt, Nele; Haenen, Vincent; De Vrieze, Tessa; De Groef, An] KU Leuven Univ Leuven, Dept Rehabil Sci, Leuven, Belgium. | - |
local.description.affiliation | [Dams, Lore; Van der Gucht, Elien; Haenen, Vincent; Van Wilgen, Paul; Meeus, Mira; De Groef, An] Pain Mot Int Res Grp, Brussels, Belgium. | - |
local.description.affiliation | [Devoogdt, Nele] UZ Leuven Univ Hosp Leuven, Ctr Lymphedema, Dept Phys Med & Rehabil, Leuven, Belgium. | - |
local.description.affiliation | [Devoogdt, Nele] UZ Leuven Univ Hosp Leuven, Dept Vasc Surg, Leuven, Belgium. | - |
local.description.affiliation | [Smeets, Ann] Univ Hosp Leuven, Dept Surg Oncol, Leuven, Belgium. | - |
local.description.affiliation | [Bernar, Koen; Morlion, Bart] Univ Hosp Leuven, Leuven Ctr Algol & Pain Management, Leuven, Belgium. | - |
local.description.affiliation | [Morlion, Bart] KU Leuven Univ Leuven, Dept Cardiovasc Sci, Sect Anaesthesiol & Algol, Leuven, Belgium. | - |
local.description.affiliation | [Godderis, Lode] Univ Leuven, Ctr Environm & Hlth, Leuven, Belgium. | - |
local.description.affiliation | [Godderis, Lode] IDEWE, External Serv Prevent & Protect Work, Leuven, Belgium. | - |
local.description.affiliation | [Fieuws, Steffen] Univ Leuven, Interuniv Ctr Biostat & Stat Bioinformat, Leuven, Belgium. | - |
local.description.affiliation | [Fieuws, Steffen] Univ Hasselt, Leuven, Belgium. | - |
local.description.affiliation | Macquarie Univ, Fac Med Hlth & Human Sci, Dept Hlth Profess, Sydney, Australia. | - |
local.description.affiliation | Univ Auckland, Fac Sci, Dept Exercise Sci, Auckland, New Zealand. | - |
local.description.affiliation | Vrije Univ Brussel, Fac Phys Educ & Physiotherapy, Dept Physiotherapy Human Physiol & Anat, Brussels, Belgium. | - |
local.description.affiliation | Transcare Transdisciplinary Pain Management Ctr, Groningen, Netherlands. | - |
local.description.affiliation | Univ Ghent, Fac Med & Hlth Sci, Dept Rehabil Sci & Physiotherapy, Ghent, Belgium. | - |
local.description.affiliation | [Dams, Lore] Univ Antwerp, Dept Rehabil Sci & Physiotherapy, Campus Drie Eiken Univ Pl 1,R315, B-2610 Antwerp, Belgium. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.fullcitation | Dams, Lore; Van der Gucht, Elien; Devoogdt, Nele; Smeets, Ann; Bernar, Koen; Morlion, Bart; Godderis, Lode; Haenen, Vincent; De Vrieze, Tessa; FIEUWS, Steffen; Moloney, Niamh; Van Wilgen, Paul; Meeus , Mira & De Groef, An (2023) Effect of pain neuroscience education after breast cancer surgery on pain, physical, and emotional functioning: a double-blinded randomized controlled trial (EduCan trial). In: PAIN, 164 (7) , p. 1489 -1501. | - |
item.embargoEndDate | 2024-07-01 | - |
item.contributor | Dams, Lore | - |
item.contributor | Van der Gucht, Elien | - |
item.contributor | Devoogdt, Nele | - |
item.contributor | Smeets, Ann | - |
item.contributor | Bernar, Koen | - |
item.contributor | Morlion, Bart | - |
item.contributor | Godderis, Lode | - |
item.contributor | Haenen, Vincent | - |
item.contributor | De Vrieze, Tessa | - |
item.contributor | FIEUWS, Steffen | - |
item.contributor | Moloney, Niamh | - |
item.contributor | Van Wilgen, Paul | - |
item.contributor | Meeus , Mira | - |
item.contributor | De Groef, An | - |
item.accessRights | Embargoed Access | - |
crisitem.journal.issn | 0304-3959 | - |
crisitem.journal.eissn | 1872-6623 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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PAIN-D-22-00566 1489..1501.pdf Restricted Access | Published version | 557.35 kB | Adobe PDF | View/Open Request a copy |
Dams 2022_EduCan primary outcome_accepted.pdf Until 2024-07-01 | Peer-reviewed author version | 1.85 MB | Adobe PDF | View/Open Request a copy |
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