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http://hdl.handle.net/1942/40755| Title: | Focal segmental glomerulosclerosis associated with the use of the IL-23 inhibitor guselkumab | Authors: | Stryckers, Marijke Van Oevelen, Stefaan Koshy, Priyanka SPRANGERS, Ben Van Craenenbroeck, Amaryllis H. |
Issue Date: | 2023 | Publisher: | OXFORD UNIV PRESS | Source: | Clinical Kidney Journal, 16 (10), p. 1701-1702 | Abstract: | We report a case of a 38-year-old man who developed a nephrotic syndrome shortly after the start of guselkumab for the treatment of plaque psoriasis. Renal biopsy showed focal segmental glomerulosclerosis (FSGS). The clinical course of our case is highly suspect for drug-induced FSGS since the nephrotic syndrome resolved after cessation of the drug without relapse (2 years of follow-up). To the best of our knowledge, this is the first case describing FSGS lesions associated with the use of an interleukin-23 inhibitor. | Notes: | Stryckers, M (corresponding author), H Hart Ziekenhuis, Dept Nephrol, Lier, Belgium. marijke.stryckers@heilighartlier.be |
Keywords: | focal segmental glomerulosclerosis;guselkumab;IL-23 | Document URI: | http://hdl.handle.net/1942/40755 | ISSN: | 2048-8505 | e-ISSN: | 2048-8513 | DOI: | 10.1093/ckj/sfad161 | ISI #: | 001031247900001 | Rights: | The Author(s) 2023. Published by Oxford University Press on behalf of the ERA. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com | Category: | A1 | Type: | Journal Contribution |
| Appears in Collections: | Research publications |
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