Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/40769
Title: | Use of Real-Time Cine MRI to Assess the Respirophasic Variation of the Inferior Vena Cava-Proof-of-Concept and Validation Against Transthoracic Echocardiography | Authors: | Bogaert, Jan BEKHUIS, Youri Rosseel, Thomas Lavaux, Stijn Dausin, Christophe Voigt, Jens-Uwe CLAESSEN, Guido Dresselaers, Tom |
Issue Date: | 2023 | Publisher: | WILEY | Source: | JOURNAL OF MAGNETIC RESONANCE IMAGING, | Status: | Early view | Abstract: | Background: In clinical practice, the right heart filling status is assessed using the respirophasic variation of the inferior vena cava (IVC) assessed by transthoracic echocardiography (TTE) showing moderate correlations with the catheter-based reference standard. Purpose: To develop and validate a similar approach using MRI. Study Type: Prospective. Population: 37 male elite cyclists (mean age 26 +/- 4 years). Field Strength/Sequence: Real-time balanced steady-state free-precession cine sequence at 1.5 Tesla. Assessment: Respirophasic variation included assessment of expiratory size of the upper hepatic part of the IVC and degree of inspiratory collapse expressed as collapsibility index (CI). The IVC was studied either in long-axis direction (TTE) or using two transverse slices, separated by 30 mm (MRI) during operator-guided deep breathing. For MRI, in addition to the TTE-like diameter, IVC area and major and minor axis diameters were also assessed, together with the corresponding CIs. Statistical Tests: Repeated measures ANOVA test with Bonferroni correction. Intraclass correlation coefficient (ICC) and Bland-Altman analysis for intrareader and inter-reader agreement. A P value <0.05 was considered statistically significant. Results: No significant differences in expiratory IVC diameter were found between TTE and MRI, i.e., 25 +/- 4 mmvs. 25 +/- 3 mm (P = 0.242), but MRI showed a higher CI, i.e., 76% +/- 14% vs. 66% +/- 14% (P < 0.05). As the IVC presented a noncircular shape, i.e., major and minor expiratory diameter of 28 +/- 4 mm and 21 +/- 4 mm, respectively, the CI varied according to the orientation, i.e., 63% +/- 27% vs. 75% +/- 16%, respectively. Alternatively, expiratory IVC area was 4.3 +/- 1.1 cm(2) and showed a significantly higher CI, i.e., 86% +/- 14% than diameter-based CI (P < 0.05). All participants showed a CI >50% with MRI versus 35/37 (94%) with TTE. ICC values ranged 0.546-0.841 for MRI and 0.545-0.704 for TTE. Conclusion: Assessment of the respirophasic IVC variation is feasible with MRI. Adding this biomarker may be of particular use in evaluating heart failure patients. Level of Evidence: 1 Technical Efficacy Stage: 2 | Notes: | Bogaert, J (corresponding author), UZ Leuven, Dept Radiol, Leuven, Belgium.; Bogaert, J (corresponding author), Katholieke Univ Leuven, Dept Imaging & Pathol, Herestr 49-B, B-3000 Leuven, Belgium. Jan.bogaert@uzleuven.be |
Keywords: | heart failure;central venous pressure;inferior vena cava | Document URI: | http://hdl.handle.net/1942/40769 | ISSN: | 1053-1807 | e-ISSN: | 1522-2586 | DOI: | 10.1002/jmri.28863 | ISI #: | 001026055000001 | Rights: | 2023 International Society for Magnetic Resonance in Medicine. | Category: | A1 | Type: | Journal Contribution |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Use of Real‐Time Cine MRI to Assess the Respirophasic Variation of the Inferior Vena Cava—Proof‐of‐Concept and Validation Against Transthoracic Echocardiography.pdf Restricted Access | Early view | 1.56 MB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.