Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/40816
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Landi, Antonio | - |
dc.contributor.author | Branca, Mattia | - |
dc.contributor.author | VRANCKX, Pascal | - |
dc.contributor.author | Leonardi, Sergio | - |
dc.contributor.author | Frigoli, Enrico | - |
dc.contributor.author | Heg, Dik | - |
dc.contributor.author | Calabro, Paolo | - |
dc.contributor.author | Esposito, Giovanni | - |
dc.contributor.author | Sardella, Gennaro | - |
dc.contributor.author | Tumscitz, Carlo | - |
dc.contributor.author | Garducci, Stefano | - |
dc.contributor.author | Ando, Giuseppe | - |
dc.contributor.author | Limbruno, Ugo | - |
dc.contributor.author | Sganzerla, Paolo | - |
dc.contributor.author | Santarelli, Andrea | - |
dc.contributor.author | Briguori, Carlo | - |
dc.contributor.author | De la Torre Hernandez, Jose M. | - |
dc.contributor.author | Pedrazzini, Giovanni | - |
dc.contributor.author | Windecker, Stephan | - |
dc.contributor.author | Valgimigli, Marco | - |
dc.date.accessioned | 2023-09-04T07:45:01Z | - |
dc.date.available | 2023-09-04T07:45:01Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2023-09-04T07:26:51Z | - |
dc.identifier.citation | CANADIAN JOURNAL OF CARDIOLOGY, 38 (10) , p. 1488 -1500 | - |
dc.identifier.uri | http://hdl.handle.net/1942/40816 | - |
dc.description.abstract | Background: The comparative effectiveness of transradial (TRA) compared with transfemoral (TFA) access in acute coronary syndrome (ACS) patients undergoing complex percutaneous coronary intervention (PCI) remains unclear. Methods: Among 8404 ACS patients in the Minimising Adverse Haemorrhagic Events by Transradial Access Site and Systemic Implementation of AngioX (MATRIX)dAccess trial, 5233 underwent noncomplex (TRA: n = 2590; TFA: n = 2643) and 1491 complex (TRA: n = 777; TFA: n = 714) PCI. Co-primary outcomes were major adverse cardiovascular events (MACE, the composite of all-cause mortality, myocardial infarction, or stroke) and the composite of MACE and Bleeding Academic Research Consortium (BARC) type 3 or 5 bleeding (net adverse cardiovascular events [NACE]) at 30 days. Results: Rates of 30-day MACE (HR 0.94, 95% CI 0.72-1.22) or NACE (HR 0.89, 95% CI 0.69-1.14) did not significantly differ between groups in the complex PCI group, whereas both primary end points were lower (HR 0.84, 95% CI 0.70-1.00; HR 0.83, 95% CI 0.70-0.98; respectively) with TRA among noncomplex PCI patients, with negative interaction testing (Pint = 0.473 and 0.666, respectively). Access-site BARC type 3 or 5 bleeding was lower with TRA, consistently among complex (HR 0.18, 95% CI 0.05-0.63) and noncomplex (HR 0.41, 95% CI 0.20-0.85) PCI patients, whereas the former group had a greater absolute risk reduction of 1.7% (number needed to treat: 59) owing to their higher absolute risk. Conclusions: Among ACS patients, PCI complexity did not affect the comparative efficacy and safety of TRA vs TFA, whereas the absolute risk reduction of access-site major bleeding was greater with TRA compared with TFA in complex as opposed to noncomplex PCI. | - |
dc.description.sponsorship | The trial was sponsored by the Società Italiana di Cardiologia Invasiva (a nonprofit organisation), which received grant support from The Medicines Company and Terumo. This substudy did not receive any direct or indirect funding. | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.rights | 2022 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved. | - |
dc.subject.other | Femoral Artery | - |
dc.subject.other | Hemorrhage | - |
dc.subject.other | Humans | - |
dc.subject.other | Radial Artery | - |
dc.subject.other | Risk Factors | - |
dc.subject.other | Treatment Outcome | - |
dc.subject.other | Acute Coronary Syndrome | - |
dc.subject.other | Percutaneous Coronary Intervention | - |
dc.title | Radial vs Femoral Access in ACS Patients Undergoing Complex PCI Is Associated With Consistent Bleeding Benefit and No Excess of Risks | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1500 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | 1488 | - |
dc.identifier.volume | 38 | - |
local.format.pages | 13 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Valgimigli, M (corresponding author), Ente Ospedal Cantonale, Cardioctr Ticino Inst, Via Tesserete 48, CH-6900 Lugano, Switzerland. | - |
dc.description.notes | marco.valgimigli@eoc.ch | - |
local.publisher.place | STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.cjca.2022.06.014 | - |
dc.identifier.pmid | 35753631 | - |
dc.identifier.isi | 001043774400001 | - |
dc.contributor.orcid | Landi, Antonio/0000-0002-0412-1083; Leonardi, | - |
dc.contributor.orcid | Sergio/0000-0002-4800-6132; ESPOSITO, Giovanni/0000-0003-0565-7127; Heg, | - |
dc.contributor.orcid | Dik/0000-0002-8766-7945 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Landi, Antonio; Pedrazzini, Giovanni; Valgimigli, Marco] Ente Osped Cantonale, Cardioctr Ticino Inst, Div Cardiol, Lugano, Switzerland. | - |
local.description.affiliation | [Branca, Mattia; Frigoli, Enrico; Heg, Dik] Univ Bern, Clin Trials Unit, Fac Med, Bern, Switzerland. | - |
local.description.affiliation | [Vranckx, Pascal] Jessa Ziekenhuis, Hartctr Hasselt, Dept Cardiol & Crit Care Med, Hasselt, Belgium. | - |
local.description.affiliation | [Vranckx, Pascal] Univ Hasselt, Fac Med & Life Sci, Hasselt, Belgium. | - |
local.description.affiliation | [Leonardi, Sergio] Univ Pavia, Pavia, Italy. | - |
local.description.affiliation | [Leonardi, Sergio] Fdn IRCCS Policlin San Matteo, Pavia, Italy. | - |
local.description.affiliation | [Calabro, Paolo] Univ Campania Luigi Vanvitelli, St Anna San Sebastiano Hosp, Div Cardiol, Dept Translat Med, Caserta, Italy. | - |
local.description.affiliation | [Esposito, Giovanni] Univ Naples Federico II, Dept Adv Biomed Sci, Naples, Italy. | - |
local.description.affiliation | [Sardella, Gennaro] Sapienza Univ Rome, Dept Cardiovasc Sci, Policlin Umberto I, Rome, Italy. | - |
local.description.affiliation | [Tumscitz, Carlo] Azienda Osped Univ Ferrara, Cardiol Unit, Cona, Italy. | - |
local.description.affiliation | [Garducci, Stefano] Vimercate Hosp, Osped Azienda Socio Sanit Terr, Unita Operat Complessa Cardiol, Vimercate, Italy. | - |
local.description.affiliation | [Ando, Giuseppe] Univ Messina, Azienda Ospedal Univ Policlin Gaetano Martino, Messina, Italy. | - |
local.description.affiliation | [Limbruno, Ugo] Misericordia Hosp, Dept Cardiol, Grosseto, Italy. | - |
local.description.affiliation | [Sganzerla, Paolo] IRCCS Ist Auxol Italiano, Osped San Luca, Milan, Italy. | - |
local.description.affiliation | [Santarelli, Andrea] Infermi Hosp, Cardiovasc Dept, Rimini, Italy. | - |
local.description.affiliation | [Briguori, Carlo] Mediterranea Cardioctr, Intervent Cardiol Unit, Naples, Italy. | - |
local.description.affiliation | [De la Torre Hernandez, Jose M.] Hosp Univ Marqu Valdecilla, Inst Invest Sanitaria Valdecilla, Santander, Spain. | - |
local.description.affiliation | [Pedrazzini, Giovanni; Valgimigli, Marco] Univ Italian Switzerland, Dept Biomed Sci, Lugano, Switzerland. | - |
local.description.affiliation | [Windecker, Stephan] Univ Bern, Dept Cardiol, Bern, Switzerland. | - |
local.uhasselt.international | yes | - |
item.contributor | Landi, Antonio | - |
item.contributor | Branca, Mattia | - |
item.contributor | VRANCKX, Pascal | - |
item.contributor | Leonardi, Sergio | - |
item.contributor | Frigoli, Enrico | - |
item.contributor | Heg, Dik | - |
item.contributor | Calabro, Paolo | - |
item.contributor | Esposito, Giovanni | - |
item.contributor | Sardella, Gennaro | - |
item.contributor | Tumscitz, Carlo | - |
item.contributor | Garducci, Stefano | - |
item.contributor | Ando, Giuseppe | - |
item.contributor | Limbruno, Ugo | - |
item.contributor | Sganzerla, Paolo | - |
item.contributor | Santarelli, Andrea | - |
item.contributor | Briguori, Carlo | - |
item.contributor | De la Torre Hernandez, Jose M. | - |
item.contributor | Pedrazzini, Giovanni | - |
item.contributor | Windecker, Stephan | - |
item.contributor | Valgimigli, Marco | - |
item.accessRights | Open Access | - |
item.fullcitation | Landi, Antonio; Branca, Mattia; VRANCKX, Pascal; Leonardi, Sergio; Frigoli, Enrico; Heg, Dik; Calabro, Paolo; Esposito, Giovanni; Sardella, Gennaro; Tumscitz, Carlo; Garducci, Stefano; Ando, Giuseppe; Limbruno, Ugo; Sganzerla, Paolo; Santarelli, Andrea; Briguori, Carlo; De la Torre Hernandez, Jose M.; Pedrazzini, Giovanni; Windecker, Stephan & Valgimigli, Marco (2022) Radial vs Femoral Access in ACS Patients Undergoing Complex PCI Is Associated With Consistent Bleeding Benefit and No Excess of Risks. In: CANADIAN JOURNAL OF CARDIOLOGY, 38 (10) , p. 1488 -1500. | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 0828-282X | - |
crisitem.journal.eissn | 1916-7075 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Radial vs Femoral Access in ACS Patients Undergoing Complex PCI Is Associated With Consistent Bleeding Benefit and No Excess of Risks.pdf Restricted Access | Published version | 2.86 MB | Adobe PDF | View/Open Request a copy |
auteursversie.pdf | Peer-reviewed author version | 2.25 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.