Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/40873
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | PRINCEN, Ken | - |
dc.contributor.author | MARIEN, Neeve | - |
dc.contributor.author | GUEDENS, Wanda | - |
dc.contributor.author | GRAULUS, Geert-Jan | - |
dc.contributor.author | ADRIAENSENS, Peter | - |
dc.date.accessioned | 2023-09-13T10:29:24Z | - |
dc.date.available | 2023-09-13T10:29:24Z | - |
dc.date.issued | 2023 | - |
dc.date.submitted | 2023-09-13T07:55:34Z | - |
dc.identifier.citation | CHEMBIOCHEM, 24 (20) (Art N° e202300149) | - |
dc.identifier.issn | 1439-4227 | - |
dc.identifier.uri | http://hdl.handle.net/1942/40873 | - |
dc.description.abstract | Successful stem cell applications could have a significant impact on the medical field, where many lives are at stake. However, the translation of stem cells to the clinic could be improved by overcoming challenges in stem cell transplantation and in vivo retention at the site of tissue damage. This review aims to showcase the most recent insights into developing hydrogels that can deliver, retain, and accommodate stem cells for tissue repair. Hydrogels can be used for tissue engineering, as their flexibility and water content makes them excellent substitutes for the native extracellular matrix. Moreover, the mechanical properties of hydrogels are highly tuneable, and recognition moieties to control cell behaviour and fate can quickly be introduced. This review covers the parameters necessary for the physicochemical design of adaptable hydrogels, the variety of (bio)materials that can be used in such hydrogels, their application in stem cell delivery and some recently developed chemistries for reversible crosslinking. Implementing physical and dynamic covalent chemistry has resulted in adaptable hydrogels that can mimic the dynamic nature of the extracellular matrix. | - |
dc.description.sponsorship | K.P. and N.M. acknowledge funding from the Research Foundation Flanders (FWO) under the form of a doctoral fellowship (project nos. 1SB1222N and 1133323N). | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.rights | 2023 Wiley-VCH GmbH. | - |
dc.subject.other | adaptable hydrogels | - |
dc.subject.other | biomaterials | - |
dc.subject.other | dynamic covalent chemistry | - |
dc.subject.other | physicochemical association | - |
dc.subject.other | stem cell retention | - |
dc.title | Hydrogels with Reversible Crosslinks for Improved Localised Stem Cell Retention: A Review | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 20 | - |
dc.identifier.volume | 24 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Adriaensens, P (corresponding author), Hasselt Univ, Inst Mat Res IMO IMOMEC, Biomol Design Grp, Agoralaan Bldg D, B-3590 Diepenbeek, Belgium. | - |
dc.description.notes | peter.adriaensens@uhasselt.be | - |
local.publisher.place | POSTFACH 101161, 69451 WEINHEIM, GERMANY | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
local.bibliographicCitation.artnr | e202300149 | - |
dc.identifier.doi | 10.1002/cbic.202300149 | - |
dc.identifier.pmid | 37220343 | - |
dc.identifier.isi | 001152023600001 | - |
dc.identifier.eissn | 1439-7633 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Princen, Ken; Marien, Neeve; Guedens, Wanda; Graulus, Geert-Jan; Adriaensens, Peter] Hasselt Univ, Inst Mat Res IMO IMOMEC, Biomol Design Grp, Agoralaan Bldg D, B-3590 Diepenbeek, Belgium. | - |
local.uhasselt.international | no | - |
item.fulltext | With Fulltext | - |
item.fullcitation | PRINCEN, Ken; MARIEN, Neeve; GUEDENS, Wanda; GRAULUS, Geert-Jan & ADRIAENSENS, Peter (2023) Hydrogels with Reversible Crosslinks for Improved Localised Stem Cell Retention: A Review. In: CHEMBIOCHEM, 24 (20) (Art N° e202300149). | - |
item.accessRights | Embargoed Access | - |
item.contributor | PRINCEN, Ken | - |
item.contributor | MARIEN, Neeve | - |
item.contributor | GUEDENS, Wanda | - |
item.contributor | GRAULUS, Geert-Jan | - |
item.contributor | ADRIAENSENS, Peter | - |
item.embargoEndDate | 2024-07-31 | - |
crisitem.journal.issn | 1439-4227 | - |
crisitem.journal.eissn | 1439-7633 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
ChemBioChem - 2023 - Princen - Hydrogels with reversible cross_links for improved localised stem cell retention a review (1) (2).pdf Until 2024-07-31 | Peer-reviewed author version | 2.14 MB | Adobe PDF | View/Open Request a copy |
Hydrogels with Reversible Crosslinks for Improved Localised Stem Cell Retention_ A Review.pdf Restricted Access | Published version | 7.53 MB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.