Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/41521
Full metadata record
DC FieldValueLanguage
dc.contributor.authorVieira, Luciana-
dc.contributor.authorSilva, Paulo Eugenio-
dc.contributor.authorde Melo, Priscilla Flavia-
dc.contributor.authorMaldaner, Vinicius-
dc.contributor.authorDurigan, Joao Q.-
dc.contributor.authorMarqueti, Rita de Cassia-
dc.contributor.authorNobrega, Otavio-
dc.contributor.authorMathur, Sunita-
dc.contributor.authorBURTIN, Chris-
dc.contributor.authorBarin, Fabricio-
dc.contributor.authorMachado-Silva, Wilcelly-
dc.contributor.authorRamalho, Sergio-
dc.contributor.authorChiappa, Gaspar R.-
dc.contributor.authorGomes, Nadia Oliveira-
dc.contributor.authorCarvalho, Celso R. F.-
dc.contributor.authorCipriano, Graziella F. B.-
dc.contributor.authorCipriano, Gerson-
dc.contributor.editorLuchette, Fred A.-
dc.date.accessioned2023-10-12T11:06:27Z-
dc.date.available2023-10-12T11:06:27Z-
dc.date.issued2023-
dc.date.submitted2023-10-12T09:34:10Z-
dc.identifier.citationCritical Care Research and Practice, 2023 , p. 1 -12 (Art N° ID 9335379)-
dc.identifier.urihttp://hdl.handle.net/1942/41521-
dc.description.abstractObjective. To investigate the effects of an early neuromuscular electrical stimulation (NMES) protocol on muscle quality and size as well as signaling mediators of muscle growth and systemic inflammation in patients with traumatic brain injury (TBI). Design. Two-arm, single-blinded, parallel-group, randomized, controlled trial with a blinded assessment. Setting. Trauma intensive care unit at a university hospital. Participants. Forty consecutive patients on mechanical ventilation (MV) secondary to TBI were prospectively recruited within the first 24 hours following admission. Interventions. (The intervention group (NMES; n = 20) received a daily session of NMES on the rectus femoris muscle for five consecutive days (55 min/each session). The control group (n = 20) received usual care. Main Outcome Measures. Muscle echogenicity and thickness were evaluated by ultrasonography. A daily blood sample was collected to assess circulating levels of insulin-like growth factor I (IGF-I), inflammatory cytokines, and matrix metalloproteinases (MMP). Results. Both groups were similar at baseline. A smaller change in muscle echogenicity and thickness (difference between Day 1 and Day 7) was found in the control group compared to the NMES group (29.9 +/- 2.1 vs. 3.0 +/- 1.2, p < 0.001; -0.79 +/- 0.12 vs. -0.01 +/- 0.06, p < 0.001, respectively). Circulating levels of IGF-I, pro-inflammatory cytokines (IFN-y), and MMP were similar between groups. Conclusion. An early NMES protocol can preserve muscle size and quality and maintain systemic levels of signaling mediators of muscle growth and inflammation in patients with TBI. (is trial is registered with https://www.ensaiosclinicos.gov.br under number RBR-2db.-
dc.description.sponsorshipThe authors thank Larissa Santana, Natalia Lucilia, and Andre Xavier for their support with data acquisition and Carla Nunes Araujo, Vinicius Caroline de Souza, and Maria de Fatima Teles Paes Landim for their technical assistance ´ with IGF-I and cytokine analysis. Tis project was co-funded by Conselho Nacional de Desenvolvimento Tecnologico ´ (CNPq 487.177/2013-4), Fundação de Ensino e Pesquisa em Ciencias da Sa ˆ ude (FEPECS 41/2013), and Fundação de ´ Amparo a Pesquisa do Distrito Federal (FAP-DF 193.000.862/2014). LV was supported by the Coordenação de Aperfeiçoamento de Pessoal de N´ıvel Superior (CAPES, PDSE-99999.004044/2015-00)-
dc.language.isoen-
dc.publisherHINDAWI LTD-
dc.rights2023 Luciana Vieira et al.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited-
dc.titleEarly Neuromuscular Electrical Stimulation Preserves Muscle Size and Quality and Maintains Systemic Levels of Signaling Mediators of Muscle Growth and Inflammation in Patients with Traumatic Brain Injury: A Randomized Clinical Trial-
dc.typeJournal Contribution-
dc.identifier.epage12-
dc.identifier.spage1-
dc.identifier.volume2023-
local.format.pages12-
local.bibliographicCitation.jcatA1-
dc.description.notesCipriano, G (corresponding author), Univ Brasilia, Fac Ceilandia, Sci & Technol Hlth Program PPGCTS, Brasilia, DF, Brazil.; Cipriano, G (corresponding author), UniEVANGEL, Human Movement & Rehabil Program, Anapolis, GO, Brazil.; Cipriano, G (corresponding author), Univ Brasilia, Fac Ceilandia, Rehabil Sci Program PPGCR, Brasilia, DF, Brazil.-
dc.description.noteslutavernard@gmail.com; pauloeugenio.bsb@gmail.com;-
dc.description.notespriscillaflavia@yahoo.com.br; viniciusmaldaner@gmail.com;-
dc.description.notesjoaodurigan@gmail.com; marqueti@gmail.com; otavionobrega@unb.br;-
dc.description.notessunita.mathur@utoronto.ca; chris.burtin@uhasselt.be;-
dc.description.notesfabriciobarin@gmail.com; wilcellym@gmail.com; shrramalho@gmail.com;-
dc.description.notesgaspar.chiappa@gmail.com; ftnadiagomes@gmail.com; cscarval@usp.br;-
dc.description.notesgrafb@unb.br; cipriano@unb.br-
local.publisher.placeADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND-
local.type.refereedRefereed-
local.type.specifiedArticle-
local.bibliographicCitation.artnrID 9335379-
dc.identifier.doi10.1155/2023/9335379-
dc.identifier.pmid37547450-
dc.identifier.isi001043418300001-
dc.contributor.orcidNobrega, Otavio T/0000-0003-1775-7176; Durigan,-
dc.contributor.orcidJoao/0000-0002-7511-5289; Marqueti, Rita de Cassia/0000-0001-9126-3882;-
dc.contributor.orcidMathur, Sunita/0000-0001-5564-9796-
local.provider.typewosris-
local.description.affiliation[Vieira, Luciana; Silva, Paulo Eugenio; de Melo, Priscilla Flavia; Maldaner, Vinicius; Durigan, Joao Q.; Marqueti, Rita de Cassia; Nobrega, Otavio; Barin, Fabricio; Machado-Silva, Wilcelly; Ramalho, Sergio; Cipriano, Graziella F. B.; Cipriano, Gerson] Univ Brasilia, Fac Ceilandia, Sci & Technol Hlth Program PPGCTS, Brasilia, DF, Brazil.-
local.description.affiliation[Vieira, Luciana; Silva, Paulo Eugenio; de Melo, Priscilla Flavia] Hosp Base Dist Fed, Phys Therapy Div, Brasilia, DF, Brazil.-
local.description.affiliation[Maldaner, Vinicius; Chiappa, Gaspar R.; Gomes, Nadia Oliveira; Cipriano, Gerson] UniEVANGEL, Human Movement & Rehabil Program, Anapolis, GO, Brazil.-
local.description.affiliation[Durigan, Joao Q.; Marqueti, Rita de Cassia; Cipriano, Graziella F. B.; Cipriano, Gerson] Univ Brasilia, Fac Ceilandia, Rehabil Sci Program PPGCR, Brasilia, DF, Brazil.-
local.description.affiliation[Nobrega, Otavio] Univ Brasilia UnB, Med Sci Grad Program PPGCM, Brasilia, DF, Brazil.-
local.description.affiliation[Mathur, Sunita] Queens Univ, Sch Rehabil Therapy, Kingston, ON, Canada.-
local.description.affiliation[Burtin, Chris] Hasselt Univ, Fac Rehabil Sci, Biomed Res Inst, Rehabil Res Ctr, Hasselt, Belgium.-
local.description.affiliation[Carvalho, Celso R. F.] Univ Sao Paulo, Sch Med, Sao Paulo, SP, Brazil.-
local.uhasselt.internationalyes-
item.fulltextWith Fulltext-
item.accessRightsOpen Access-
item.fullcitationVieira, Luciana; Silva, Paulo Eugenio; de Melo, Priscilla Flavia; Maldaner, Vinicius; Durigan, Joao Q.; Marqueti, Rita de Cassia; Nobrega, Otavio; Mathur, Sunita; BURTIN, Chris; Barin, Fabricio; Machado-Silva, Wilcelly; Ramalho, Sergio; Chiappa, Gaspar R.; Gomes, Nadia Oliveira; Carvalho, Celso R. F.; Cipriano, Graziella F. B. & Cipriano, Gerson (2023) Early Neuromuscular Electrical Stimulation Preserves Muscle Size and Quality and Maintains Systemic Levels of Signaling Mediators of Muscle Growth and Inflammation in Patients with Traumatic Brain Injury: A Randomized Clinical Trial. In: Critical Care Research and Practice, 2023 , p. 1 -12 (Art N° ID 9335379).-
item.contributorVieira, Luciana-
item.contributorSilva, Paulo Eugenio-
item.contributorde Melo, Priscilla Flavia-
item.contributorMaldaner, Vinicius-
item.contributorDurigan, Joao Q.-
item.contributorMarqueti, Rita de Cassia-
item.contributorNobrega, Otavio-
item.contributorMathur, Sunita-
item.contributorBURTIN, Chris-
item.contributorBarin, Fabricio-
item.contributorMachado-Silva, Wilcelly-
item.contributorRamalho, Sergio-
item.contributorChiappa, Gaspar R.-
item.contributorGomes, Nadia Oliveira-
item.contributorCarvalho, Celso R. F.-
item.contributorCipriano, Graziella F. B.-
item.contributorCipriano, Gerson-
item.contributorLuchette, Fred A.-
crisitem.journal.issn2090-1305-
crisitem.journal.eissn2090-1313-
Appears in Collections:Research publications
Files in This Item:
File Description SizeFormat 
CCRP9335379 1..12.pdfPublished version507.9 kBAdobe PDFView/Open
Show simple item record

WEB OF SCIENCETM
Citations

1
checked on Jul 26, 2024

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.