Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/41527
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Finlayson, Marcia | - |
dc.contributor.author | FEYS, Peter | - |
dc.contributor.author | Dalgas, Ulrik | - |
dc.contributor.author | KOS, Daphne | - |
dc.date.accessioned | 2023-10-12T13:23:36Z | - |
dc.date.available | 2023-10-12T13:23:36Z | - |
dc.date.issued | 2023 | - |
dc.date.submitted | 2023-10-12T12:55:25Z | - |
dc.identifier.citation | Multiple Sclerosis Journal, 29 (9) , p. 1186 -1194 | - |
dc.identifier.uri | http://hdl.handle.net/1942/41527 | - |
dc.description.abstract | Background:Rehabilitation is an essential health care service and a critical component of comprehensive multiple sclerosis (MS) care. Objective:As part of a 2-day meeting hosted by the International Advisory Committee on Clinical Trials in MS in December 2022, a panel initiated a discussion on the conceptual and practical issues related to selecting intermediate outcomes for clinical trials of MS rehabilitation interventions. Results:The overarching goal of rehabilitation - optimal functioning - was acknowledged as a complex biopsychosocial phenomenon that varies with patient priorities and environmental context. This complexity means that multiple causal pathways and potential intermediate outcomes must be carefully considered during the design of clinical trials in MS rehabilitation that aim to improve functioning. In addition, practical issues must be considered such as psychometric properties of outcome measures, measure type, and characteristics of the target population, including severity of dysfunction. Conclusion:This article uses the International Classification of Functioning, Disability and Health as a foundation for determining relevant intermediate outcomes for clinical trials of MS rehabilitation interventions. | - |
dc.description.sponsorship | The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: The International Advisory Committee on Clinical Trials in Multiple Sclerosis and the International Conference on Innovations in Clinical Trial Design & Enhancing Inclusivity of Clinical Trial Populations were supported by the National Multiple Sclerosis Society and the European Committee for Treatment and Research in Multiple Sclerosis. There was no involvement of the sponsors in the design, collection, analysis or interpretation of data discussed at the Conference. The opinions expressed are those of the authors. Open access was made possible by the participation of Queen’s University in the Canadian Research Knowledge Network. | - |
dc.language.iso | en | - |
dc.publisher | SAGE PUBLICATIONS LTD | - |
dc.rights | The Author(s), 2023 | - |
dc.subject.other | Multiple sclerosis | - |
dc.subject.other | rehabilitation | - |
dc.subject.other | functional status | - |
dc.subject.other | outcome measure | - |
dc.subject.other | clinical trial | - |
dc.subject.other | International Classification of Functioning | - |
dc.subject.other | Disability and Health | - |
dc.title | Intermediate outcomes for clinical trials of multiple sclerosis rehabilitation interventions: Conceptual and practical considerations | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1194 | - |
dc.identifier.issue | 9 | - |
dc.identifier.spage | 1186 | - |
dc.identifier.volume | 29 | - |
local.format.pages | 9 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Finlayson, M (corresponding author), Queens Univ, Sch Rehabil Therapy, 31 George St, Kingston, ON K7L 3N6, Canada. | - |
dc.description.notes | marcia.finlayson@queensu.ca | - |
local.publisher.place | 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
dc.identifier.doi | 10.1177/13524585231189674 | - |
dc.identifier.pmid | 37555489 | - |
dc.identifier.isi | 001045112500020 | - |
dc.contributor.orcid | Dalgas, Ulrik/0000-0003-4132-2789; Kos, Daphne/0000-0003-3566-2269 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Finlayson, Marcia] Queens Univ, Sch Rehabil Therapy, Kingston, ON, Canada. | - |
local.description.affiliation | [Feys, Peter] Hasselt Univ, Fac Rehabil Sci, REVAL Rehabil Res Ctr, Hasselt, Belgium. | - |
local.description.affiliation | [Feys, Peter] UMSC Hasselt, Pelt, Belgium. | - |
local.description.affiliation | [Dalgas, Ulrik] Aarhus Univ, Dept Publ Hlth, Exercise Biol, Aarhus, Denmark. | - |
local.description.affiliation | [Kos, Daphne] Katholieke Univ Leuven, Dept Rehabil Sci, Leuven, Belgium. | - |
local.description.affiliation | [Kos, Daphne] Natl Multiple Sclerosis Ctr Melsbroek, Steenokkerzeel, Belgium. | - |
local.uhasselt.international | yes | - |
item.fullcitation | Finlayson, Marcia; FEYS, Peter; Dalgas, Ulrik & KOS, Daphne (2023) Intermediate outcomes for clinical trials of multiple sclerosis rehabilitation interventions: Conceptual and practical considerations. In: Multiple Sclerosis Journal, 29 (9) , p. 1186 -1194. | - |
item.contributor | Finlayson, Marcia | - |
item.contributor | FEYS, Peter | - |
item.contributor | Dalgas, Ulrik | - |
item.contributor | KOS, Daphne | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
crisitem.journal.issn | 1352-4585 | - |
crisitem.journal.eissn | 1477-0970 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Intermediate outcomes for clinical trials of multiple sclerosis rehabilitation interventions_ Conceptual and practical considerations.pdf | Published version | 849.49 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.