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http://hdl.handle.net/1942/42330
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DC Field | Value | Language |
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dc.contributor.author | BALISTIERI SANTINELLI, Felipe | - |
dc.contributor.author | RAMARI FERREIRA, Cintia | - |
dc.contributor.author | PONCELET, Marie | - |
dc.contributor.author | SEVERIJNS, Deborah | - |
dc.contributor.author | KOS, Daphne | - |
dc.contributor.author | Pau, Massimiliano | - |
dc.contributor.author | Kalron, Alon | - |
dc.contributor.author | MEYNS, Pieter | - |
dc.contributor.author | FEYS, Peter | - |
dc.date.accessioned | 2024-02-07T09:10:43Z | - |
dc.date.available | 2024-02-07T09:10:43Z | - |
dc.date.issued | 2024 | - |
dc.date.submitted | 2024-01-18T11:04:22Z | - |
dc.identifier.citation | NEUROREHABILITATION AND NEURAL REPAIR, | - |
dc.identifier.uri | http://hdl.handle.net/1942/42330 | - |
dc.description.abstract | Background: Gait characteristics and their changes during the 6-minute walking test (6MWT) in people with multiple sclerosis (pwMS) have been described in the literature, which one may refer to as walking fatigability in the body function level of the International Classification of Functioning, Disability, and Health. However, whether these metrics are reliable is unknown. Objective: To investigate the between-day reliability of the gait characteristics and their changes in pwMS and healthy controls (HCs). Methods: Forty-nine pwMS (EDSS 4.82 ± 1.22 and 54.7 ± 9.36 years) and 23 HCs (50.6 ± 6.1 years) performed the 6MWT, as fast as possible but safely while wearing Inertial Measurement Units. Gait characteristics were measured in the pace, rhythm, variability, asymmetry, kinematics, coordination, and postural control domains and were obtained in intervals of 1 minute during the 6MWT. In addition, gait characteristics change in the last minute compared with the first minute were calculated for all gait variables using a fatigability index (ie, distance walking index). The intraclass correlation coefficient (ICC), Bland-Altman Plots, and Standard error of measurement were applied to investigate reliability. Results: Reliability of gait characteristics, minute-by-minute, and for their changes (ie, using the fatigability index) ranged from poor to excellent (pwMS: ICC 0.46-0.96; HC: ICC 0.09-0.97 and pwMS: ICC 0-0.72; HC: ICC 0-0.77, respectively). Conclusion: Besides coordination, at least 1 variable of each gait domain showed an ICC of moderate or good reliability for gait characteristics changes in both pwMS and HC. These metrics can be incorporated into future clinical trials and research on walking fatigability.Clinical Trial Registration: NCT05412043. | - |
dc.description.sponsorship | The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported by Research Foundation - Flanders (#11O5823N), the MS LIGA Flanders (steunfonds), and the King Beaudouin foundation (fundClaire Fauconnier). Acknowledgments The authors would like to thank all the participants and clinical MS centers of the study for participation, the research foundations for their financial support (Research Foundation—Flanders, MS LIGA Flanders, and the King Beaudouin foundation), and the physiotherapy master students of the University of Hasselt in assisting with data collection. | - |
dc.language.iso | en | - |
dc.publisher | SAGE PUBLICATIONS INC | - |
dc.rights | The Author(s) 2024 Article reuse guidelines: sagepub.com/journals-permissions | - |
dc.subject.other | day-to-day variability | - |
dc.subject.other | fatigue | - |
dc.subject.other | gait | - |
dc.subject.other | multiple sclerosis | - |
dc.subject.other | psychometrics | - |
dc.subject.other | walking | - |
dc.title | Between-Day Reliability of the Gait Characteristics and Their Changes During the 6-Minute Walking Test in People With Multiple Sclerosis | - |
dc.type | Journal Contribution | - |
local.format.pages | 12 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Santinelli, FB (corresponding author), Hasselt Univ, Fac Rehabil Sci, REVAL Res Ctr, Wetenschapspk 5-7, B-3590 Diepenbeek, Belgium. | - |
dc.description.notes | felipe.balistierisantinelli@uhasselt.be | - |
local.publisher.place | 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.status | Early view | - |
dc.identifier.doi | 10.1177/15459683231222412 | - |
dc.identifier.pmid | 38229519 | - |
dc.identifier.isi | 001144916200001 | - |
local.provider.type | PubMed | - |
local.description.affiliation | [Santinelli, Felipe Balistieri; Ramari, Cintia; Severijns, Deborah; Meyns, Pieter; Feys, Peter] Hasselt Univ, Fac Rehabil Sci, REVAL Rehabil Res Ctr, Hasselt, Belgium. | - |
local.description.affiliation | [Santinelli, Felipe Balistieri; Ramari, Cintia; Severijns, Deborah; Feys, Peter] UMSC, Hasselt Pelt, Belgium. | - |
local.description.affiliation | [Poncelet, Marie] Maastricht Univ, Fac Hlth Med & Life Sci, Maastricht, Netherlands. | - |
local.description.affiliation | [Severijns, Deborah] Noorderhart Rehabil & MS Ctr, Pelt, Belgium. | - |
local.description.affiliation | [Kos, Daphne] Natl MS Ctr Melsbroek, Melsbroek, Belgium. | - |
local.description.affiliation | [Kos, Daphne] Katholieke Univ Leuven, Dept Rehabil Sci, Leuven, Belgium. | - |
local.description.affiliation | [Pau, Massimiliano] Univ Cagliari, Dept Mech Chem & Mat Engn, Cagliari, Italy. | - |
local.description.affiliation | [Kalron, Alon] Tel Aviv Univ, Sch Hlth Profess, Dept Phys Therapy, Fac Med, Tel Aviv, Israel. | - |
local.description.affiliation | [Kalron, Alon] Tel Aviv Univ, Sagol Sch Neurosci, Tel Aviv, Israel. | - |
local.description.affiliation | [Santinelli, Felipe Balistieri] Hasselt Univ, Fac Rehabil Sci, REVAL Res Ctr, Wetenschapspk 5-7, B-3590 Diepenbeek, Belgium. | - |
local.uhasselt.international | yes | - |
item.accessRights | Restricted Access | - |
item.fullcitation | BALISTIERI SANTINELLI, Felipe; RAMARI FERREIRA, Cintia; PONCELET, Marie; SEVERIJNS, Deborah; KOS, Daphne; Pau, Massimiliano; Kalron, Alon; MEYNS, Pieter & FEYS, Peter (2024) Between-Day Reliability of the Gait Characteristics and Their Changes During the 6-Minute Walking Test in People With Multiple Sclerosis. In: NEUROREHABILITATION AND NEURAL REPAIR,. | - |
item.fulltext | With Fulltext | - |
item.contributor | BALISTIERI SANTINELLI, Felipe | - |
item.contributor | RAMARI FERREIRA, Cintia | - |
item.contributor | PONCELET, Marie | - |
item.contributor | SEVERIJNS, Deborah | - |
item.contributor | KOS, Daphne | - |
item.contributor | Pau, Massimiliano | - |
item.contributor | Kalron, Alon | - |
item.contributor | MEYNS, Pieter | - |
item.contributor | FEYS, Peter | - |
crisitem.journal.issn | 0888-4390 | - |
Appears in Collections: | Research publications |
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santinelli-et-al-2024-between-day-reliability-of-the-gait-characteristics-and-their-changes-during-the-6-minute-walking.pdf Restricted Access | Early view | 1.43 MB | Adobe PDF | View/Open Request a copy |
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