Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/42864
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dc.contributor.authorWILLEMS, Emily-
dc.contributor.authorSCHEPERS, Melissa-
dc.contributor.authorAit-Tihyaty, M.-
dc.contributor.authorVANMIERLO, Tim-
dc.date.accessioned2024-05-06T11:21:33Z-
dc.date.available2024-05-06T11:21:33Z-
dc.date.issued2023-
dc.date.submitted2024-05-06T07:32:44Z-
dc.identifier.citationGLIA, 71 (S1) , p. E791-
dc.identifier.urihttp://hdl.handle.net/1942/42864-
dc.description.abstractBackground: Sphingosine-1-phosphate (S1P1) receptor modulators are used clinically to treat relapsing forms of multiple sclerosis (MS). Selective functional antagonism of the S1PR1 subtype by ponesimod prevents lymphocyte egression from lymph nodes, hence hampering neuroinflammation in MS. Recent findings suggest a potential additional role for ponesimod in the Central Nervous System (CNS) in the differentiation of oligodendrocyte precursor cells (OPC) into mature myelinating oligodendrocytes, and therefore potentially having some effects on remyelination.-
dc.language.isoen-
dc.publisherWILEY-
dc.titleThe Monoselective Sphingosine-1-Phosphate Receptor-1 Modulator Ponesimod Enhances Remyelination in the Cuprizone Model of Demyelination-
dc.typeJournal Contribution-
local.bibliographicCitation.conferencedateJUL 08-11, 2023-
local.bibliographicCitation.conferencename16th European Meeting on Glial Cells in Health and Disease-
local.bibliographicCitation.conferenceplaceBerlin, GERMANY-
dc.identifier.issueS1-
dc.identifier.spageE791-
dc.identifier.volume71-
local.format.pages1-
local.bibliographicCitation.jcatM-
local.publisher.place111 RIVER ST, HOBOKEN 07030-5774, NJ USA-
local.type.refereedRefereed-
local.type.specifiedMeeting Abstract-
dc.identifier.isi001191372500660-
local.provider.typewosris-
local.description.affiliation[Willems, E.; Schepers, M.; Vanmierlo, T.] Hasselt Univ, Biomed Res Inst, Hasselt, Belgium.-
local.description.affiliation[Willems, E.; Schepers, M.; Vanmierlo, T.] Maastricht Univ, Sch Mental Hlth & Neurosci, Maastricht, Netherlands.-
local.description.affiliation[Ait-Tihyaty, M.] Janssen Res Dev, Titusville, FL USA.-
local.uhasselt.internationalyes-
item.fullcitationWILLEMS, Emily; SCHEPERS, Melissa; Ait-Tihyaty, M. & VANMIERLO, Tim (2023) The Monoselective Sphingosine-1-Phosphate Receptor-1 Modulator Ponesimod Enhances Remyelination in the Cuprizone Model of Demyelination. In: GLIA, 71 (S1) , p. E791.-
item.fulltextWith Fulltext-
item.contributorWILLEMS, Emily-
item.contributorSCHEPERS, Melissa-
item.contributorAit-Tihyaty, M.-
item.contributorVANMIERLO, Tim-
item.accessRightsRestricted Access-
crisitem.journal.issn0894-1491-
crisitem.journal.eissn1098-1136-
Appears in Collections:Research publications
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