Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/43148
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dc.contributor.authorBacker, MD-
dc.contributor.authorSengar, M-
dc.contributor.authorMathews, V-
dc.contributor.authorSalvaggio, S-
dc.contributor.authorDELTUVAITE-THOMAS, Vaiva-
dc.contributor.authorChiem, JC-
dc.contributor.authorSaad, ED-
dc.contributor.authorBUYSE, Marc-
dc.date.accessioned2024-06-14T07:57:20Z-
dc.date.available2024-06-14T07:57:20Z-
dc.date.issued2024-
dc.date.submitted2024-06-14T07:35:33Z-
dc.identifier.citationClinical Trials, 21 (2) , p. 180 -188-
dc.identifier.urihttp://hdl.handle.net/1942/43148-
dc.description.abstractShowing "similar efficacy" of a less intensive treatment typically requires a non-inferiority trial. Yet such trials may be challenging to design and conduct. In acute promyelocytic leukemia, great progress has been achieved with the introduction of targeted therapies, but toxicity remains a major clinical issue. There is a pressing need to show the favorable benefit/risk of less intensive treatment regimens.-
dc.description.sponsorshipThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported, in part, by the Government of Wallonia, Belgium (Grant No. BioWin Consortium Agreement No. 7979).-
dc.language.isoen-
dc.publisherSAGE PUBLICATIONS LTD-
dc.rightsThe Author(s) 2023-
dc.subject.otherGeneralized pairwise comparisons-
dc.subject.otherprioritized outcomes-
dc.subject.othernet treatment benefit-
dc.subject.othernon-inferiority-
dc.subject.otherbenefit/risk-
dc.subject.otheracute promyelocytic leukemia-
dc.titleDesign of a clinical trial using generalized pairwise comparisons to test a less intensive treatment regimen-
dc.typeJournal Contribution-
dc.identifier.epage188-
dc.identifier.issue2-
dc.identifier.spage180-
dc.identifier.volume21-
local.bibliographicCitation.jcatA1-
local.publisher.place1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND-
local.type.refereedRefereed-
local.type.specifiedArticle-
dc.identifier.doi10.1177/17407745231206465-
dc.identifier.pmid37877379-
dc.identifier.isi001087484500001-
local.provider.typeWeb of Science-
local.uhasselt.internationalyes-
item.contributorBacker, MD-
item.contributorSengar, M-
item.contributorMathews, V-
item.contributorSalvaggio, S-
item.contributorDELTUVAITE-THOMAS, Vaiva-
item.contributorChiem, JC-
item.contributorSaad, ED-
item.contributorBUYSE, Marc-
item.accessRightsOpen Access-
item.fulltextWith Fulltext-
item.validationecoom 2024-
item.fullcitationBacker, MD; Sengar, M; Mathews, V; Salvaggio, S; DELTUVAITE-THOMAS, Vaiva; Chiem, JC; Saad, ED & BUYSE, Marc (2024) Design of a clinical trial using generalized pairwise comparisons to test a less intensive treatment regimen. In: Clinical Trials, 21 (2) , p. 180 -188.-
crisitem.journal.issn1740-7745-
crisitem.journal.eissn1740-7753-
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