Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/43148
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DC Field | Value | Language |
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dc.contributor.author | Backer, MD | - |
dc.contributor.author | Sengar, M | - |
dc.contributor.author | Mathews, V | - |
dc.contributor.author | Salvaggio, S | - |
dc.contributor.author | DELTUVAITE-THOMAS, Vaiva | - |
dc.contributor.author | Chiem, JC | - |
dc.contributor.author | Saad, ED | - |
dc.contributor.author | BUYSE, Marc | - |
dc.date.accessioned | 2024-06-14T07:57:20Z | - |
dc.date.available | 2024-06-14T07:57:20Z | - |
dc.date.issued | 2024 | - |
dc.date.submitted | 2024-06-14T07:35:33Z | - |
dc.identifier.citation | Clinical Trials, 21 (2) , p. 180 -188 | - |
dc.identifier.uri | http://hdl.handle.net/1942/43148 | - |
dc.description.abstract | Showing "similar efficacy" of a less intensive treatment typically requires a non-inferiority trial. Yet such trials may be challenging to design and conduct. In acute promyelocytic leukemia, great progress has been achieved with the introduction of targeted therapies, but toxicity remains a major clinical issue. There is a pressing need to show the favorable benefit/risk of less intensive treatment regimens. | - |
dc.description.sponsorship | The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported, in part, by the Government of Wallonia, Belgium (Grant No. BioWin Consortium Agreement No. 7979). | - |
dc.language.iso | en | - |
dc.publisher | SAGE PUBLICATIONS LTD | - |
dc.rights | The Author(s) 2023 | - |
dc.subject.other | Generalized pairwise comparisons | - |
dc.subject.other | prioritized outcomes | - |
dc.subject.other | net treatment benefit | - |
dc.subject.other | non-inferiority | - |
dc.subject.other | benefit/risk | - |
dc.subject.other | acute promyelocytic leukemia | - |
dc.title | Design of a clinical trial using generalized pairwise comparisons to test a less intensive treatment regimen | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 188 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 180 | - |
dc.identifier.volume | 21 | - |
local.bibliographicCitation.jcat | A1 | - |
local.publisher.place | 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1177/17407745231206465 | - |
dc.identifier.pmid | 37877379 | - |
dc.identifier.isi | 001087484500001 | - |
local.provider.type | Web of Science | - |
local.uhasselt.international | yes | - |
item.fullcitation | Backer, MD; Sengar, M; Mathews, V; Salvaggio, S; DELTUVAITE-THOMAS, Vaiva; Chiem, JC; Saad, ED & BUYSE, Marc (2024) Design of a clinical trial using generalized pairwise comparisons to test a less intensive treatment regimen. In: Clinical Trials, 21 (2) , p. 180 -188. | - |
item.fulltext | With Fulltext | - |
item.contributor | Backer, MD | - |
item.contributor | Sengar, M | - |
item.contributor | Mathews, V | - |
item.contributor | Salvaggio, S | - |
item.contributor | DELTUVAITE-THOMAS, Vaiva | - |
item.contributor | Chiem, JC | - |
item.contributor | Saad, ED | - |
item.contributor | BUYSE, Marc | - |
item.accessRights | Open Access | - |
crisitem.journal.issn | 1740-7745 | - |
crisitem.journal.eissn | 1740-7753 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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backer-et-al-2023-design-of-a-clinical-trial-using-generalized-pairwise-comparisons-to-test-a-less-intensive-treatment.pdf | Published version | 1.79 MB | Adobe PDF | View/Open |
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