Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/43334
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Minter, Maria | - |
dc.contributor.author | van Odijk, Jenny | - |
dc.contributor.author | Augustin, Hanna | - |
dc.contributor.author | VILACA CAVALLARI MACHADO, Felipe | - |
dc.contributor.author | Franssen, Frits M. E. | - |
dc.contributor.author | SPRUIT, Martijn A. | - |
dc.contributor.author | Vanfleteren, Lowie E. G. W. | - |
dc.date.accessioned | 2024-07-05T11:03:15Z | - |
dc.date.available | 2024-07-05T11:03:15Z | - |
dc.date.issued | 2024 | - |
dc.date.submitted | 2024-07-05T08:46:21Z | - |
dc.identifier.citation | International Journal of Chronic Obstructive Pulmonary Disease, 19 , p. 1291 -1302 | - |
dc.identifier.uri | http://hdl.handle.net/1942/43334 | - |
dc.description.abstract | Background: Alterations in body weight and composition are common in patients with chronic obstructive pulmonary disease (COPD) and are independent predictors for morbidity and mortality. Low vitamin D status is also more prevalent in patients with COPD compared to controls and has been related to lower lung function, muscle atrophy and impaired musculoskeletal function. This study aimed to evaluate the association between vitamin D levels and status with body composition (BC), as well as with its changes over time. Patients and Methods: Patients with COPD and controls without COPD, participating in the Individualized COPD Evaluation in relation to Ageing (ICE-Age) study, a prospective observational study, were included. Plasma 25-hydroxyvitamin D (25(OH)D) was measured at baseline and BC was measured by dual -energy X-ray absorptiometry scan, at baseline and after two years of follow-up. Multiple linear regression analyses were performed to assess the relationships between 25(OH)D (nmol/l) and longitudinal changes in BMI, fat -free mass index (FFMI), fat mas index (FMI) and bone mineral density (BMD). Results: A total of 192 patients with COPD (57% males, mean +/- SD age, 62 +/- 7, FEV1, 49 +/- 16% predicted) and 199 controls (45% males, mean +/- SD age 61 +/- 7) were included in this study. Vitamin D levels were significantly lower in patients with COPD (64 +/- 26 nmol/L, 95% CI 60-68 nmol/L versus 75 +/- 25 nmol/L, 95% CI 72-79 nmol/L) compared to controls. Both patients and controls presented a significant decline in FFMI and T -score hip, but vitamin D level or status did not determine differences in BC or changes in BC over time in either COPD or controls. Conclusion: Vitamin D status was not associated with BC or longitudinal changes in BC. However, vitamin D insufficiency and low BMD were more prevalent in patients with COPD compared to controls. | - |
dc.description.sponsorship | FF reports grants and personal fees from AstraZeneca, grants, and personal fees from Chiesi, grants and personal fees from GlaxoSmithKline, personal fees from Pieris, grants and personal fees from Sanofi, outside the submitted work. MAS reports grants and/or fees from Netherlands Lung Foundation Netherlands, Stichting Astma Bestrijding, Boehringer Ingelheim, AstraZeneca, Chiesi, GSK, Sanofi and TEVA, all paid to the institution and all outside the submitted work. LEGWV reports personal fees for lectures and/or advisory boards from AstraZeneca, GSK, Chiesi, Pulmonx, Novartis, Boehringer, Menarini, Grifols and reports research grants from AstraZeneca paid to the institution, all outside the submitted work. The authors report no other conflicts of interest in this work. | - |
dc.language.iso | en | - |
dc.publisher | DOVE MEDICAL PRESS LTD | - |
dc.rights | 2024 Minter et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms. php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php) | - |
dc.subject.other | chronic obstructive pulmonary disease | - |
dc.subject.other | chronic obstructive pulmonary disease | - |
dc.subject.other | body composition | - |
dc.subject.other | body composition | - |
dc.subject.other | vitamin D | - |
dc.subject.other | vitamin D | - |
dc.subject.other | longitudinal changes | - |
dc.subject.other | longitudinal changes | - |
dc.subject.other | fat-free mass | - |
dc.subject.other | fat-free mass | - |
dc.subject.other | bone mineral density | - |
dc.subject.other | bone mineral density | - |
dc.title | Vitamin D Status and Longitudinal Changes in Body Composition in Patients with Chronic Obstructive Pulmonary Disease - A Prospective Observational Study | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1302 | - |
dc.identifier.spage | 1291 | - |
dc.identifier.volume | 19 | - |
local.format.pages | 12 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Minter, M (corresponding author), SV Hosp Grp, Angered Hosp, Dept Lung Med, S-42422 Angered, Sweden. | - |
dc.description.notes | maria.minter@gu.se | - |
local.publisher.place | PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.2147/COPD.S458102 | - |
dc.identifier.pmid | 38895044 | - |
dc.identifier.isi | 001244947200001 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Minter, Maria; van Odijk, Jenny; Augustin, Hanna; Vanfleteren, Lowie E. G. W.] Univ Gothenburg, Inst Med, Sahlgrenska Acad, Dept Internal Med & Clin Nutr, S-40530 Gothenburg, Sweden. | - |
local.description.affiliation | [Minter, Maria] SV Hosp Grp, Angered Hosp, Dept Lung Med, S-42422 Angered, Sweden. | - |
local.description.affiliation | [Machado, Felipe V. C.] Hasselt Univ, Fac Rehabil Sci, Rehabil Res Ctr REVAL, Diepenbeek, Belgium. | - |
local.description.affiliation | [Machado, Felipe V. C.] Hasselt Univ, Biomed Res Inst BIOMED, Fac Med & Life Sci, Diepenbeek, Belgium. | - |
local.description.affiliation | [Franssen, Frits M. E.; Spruit, Martijn A.; Vanfleteren, Lowie E. G. W.] Ciro, Dept Res & Dev, Horn, Netherlands. | - |
local.description.affiliation | [Franssen, Frits M. E.; Spruit, Martijn A.; Vanfleteren, Lowie E. G. W.] Maastricht Univ Med Ctr, Dept Resp Med, Maastricht, Netherlands. | - |
local.description.affiliation | [Franssen, Frits M. E.; Spruit, Martijn A.] Maastricht Univ Med Ctr, Fac Hlth Med & Life Sci, Sch Nutr & Translat Res Metab NUTRIM, Dept Resp Med, Maastricht, Netherlands. | - |
local.uhasselt.international | yes | - |
item.fullcitation | Minter, Maria; van Odijk, Jenny; Augustin, Hanna; VILACA CAVALLARI MACHADO, Felipe; Franssen, Frits M. E.; SPRUIT, Martijn A. & Vanfleteren, Lowie E. G. W. (2024) Vitamin D Status and Longitudinal Changes in Body Composition in Patients with Chronic Obstructive Pulmonary Disease - A Prospective Observational Study. In: International Journal of Chronic Obstructive Pulmonary Disease, 19 , p. 1291 -1302. | - |
item.contributor | Minter, Maria | - |
item.contributor | van Odijk, Jenny | - |
item.contributor | Augustin, Hanna | - |
item.contributor | VILACA CAVALLARI MACHADO, Felipe | - |
item.contributor | Franssen, Frits M. E. | - |
item.contributor | SPRUIT, Martijn A. | - |
item.contributor | Vanfleteren, Lowie E. G. W. | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
crisitem.journal.issn | 1178-2005 | - |
crisitem.journal.eissn | 1178-2005 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
COPD_A_458102 1291..1302.pdf | Published version | 1.43 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.