Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/43370
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dc.contributor.authorCROONS, Hanne-
dc.contributor.authorMARTENS, Dries-
dc.contributor.authorVAN DER STUKKEN, Charlotte-
dc.contributor.authorSLEURS, Hanne-
dc.contributor.authorRASKING, Leen-
dc.contributor.authorPEUSENS, Martien-
dc.contributor.authorRENAERS, Eleni-
dc.contributor.authorPLUSQUIN, Michelle-
dc.contributor.authorNAWROT, Tim-
dc.date.accessioned2024-07-15T07:57:11Z-
dc.date.available2024-07-15T07:57:11Z-
dc.date.issued2024-
dc.date.submitted2024-07-15T06:10:26Z-
dc.identifier.citationFrontiers in pediatrics, 12 (Art N° 1358272)-
dc.identifier.urihttp://hdl.handle.net/1942/43370-
dc.description.abstractTelomere length (TL), a marker of cellular aging, has been studied in adults with regard to its connection to cognitive function. However, little is known about the association between TL and cognitive development in children. This study investigated the interplay between TL and cognitive functioning in 283 Belgian children aged four to six years of the Environmental Influence on Aging in Early Life (ENVIRONAGE) birth cohort. Child leukocyte TL was measured using qPCR, while cognitive functioning, including attention and memory, was assessed using the Cambridge Neuropsychological Test Automated Battery (CANTAB). Linear regression models were employed to examine the association between TL and cognitive outcomes, adjusting for potential confounders. We found an inverse association between TL and the spatial errors made during the Motor Screening task (p = 0.017), indicating a higher motor accuracy in children with longer telomeres. No significant associations were found between TL and other cognitive outcomes. Our results suggest a specific link between TL and motor accuracy but not with the other cognitive domains.-
dc.description.sponsorshipFunding The author(s) declare financial support was received for the research, authorship, and/or publication of this article. ENVIRONAGE is supported by grants of the Research Foundation, Belgium (Grant No. N1518119, No. G082317N and No. 1523817N). DM holds a postdoctoral grant by the Flemish Scientific Fund (FWO grant 12X9623N). LR acknowledges funding from the Special Research Fund (Bijzonder Onderzoeksfonds, BOF) for a doctoral fellowship: BOF20DOC15. Acknowledgments The researchers would like to thank ENVIRONAGE participants, all the ENVIRONAGE follow-up study researchers, midwives, and the staff of the maternity ward of East-Limburg Hospital in Genk.-
dc.language.isoen-
dc.publisherFRONTIERS MEDIA SA-
dc.rights2024 Croons, Martens, Vanderstukken, Sleurs, Rasking, Peusens, Renaers, Plusquin and Nawrot. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.-
dc.subject.othercognition-
dc.subject.othertelomere-
dc.subject.otherattention-
dc.subject.otherchildhood-
dc.subject.otherENVIRONAGE-
dc.titleTelomere length in early childhood and its association with attention: a study in 4-6 year old children-
dc.typeJournal Contribution-
dc.identifier.volume12-
local.format.pages7-
local.bibliographicCitation.jcatA1-
dc.description.notesNawrot, TS (corresponding author), Hasselt Univ, Ctr Environm Sci, Hasselt, Belgium.; Nawrot, TS (corresponding author), Univ Leuven, KU Leuven, Dept Publ Hlth, Leuven, Belgium.-
dc.description.notestim.nawrot@uhasselt.be-
local.publisher.placeAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND-
local.type.refereedRefereed-
local.type.specifiedArticle-
local.bibliographicCitation.artnr1358272-
dc.identifier.doi10.3389/fped.2024.1358272-
dc.identifier.pmid38919841-
dc.identifier.isi001253113600001-
local.provider.typewosris-
local.description.affiliation[Croons, Hanne; Martens, Dries S.; Vanderstukken, Charlotte; Sleurs, Hanne; Rasking, Leen; Peusens, Martien; Renaers, Eleni; Plusquin, Michelle; Nawrot, Tim S.] Hasselt Univ, Ctr Environm Sci, Hasselt, Belgium.-
local.description.affiliation[Nawrot, Tim S.] Univ Leuven, KU Leuven, Dept Publ Hlth, Leuven, Belgium.-
local.uhasselt.internationalno-
item.contributorCROONS, Hanne-
item.contributorMARTENS, Dries-
item.contributorVAN DER STUKKEN, Charlotte-
item.contributorSLEURS, Hanne-
item.contributorRASKING, Leen-
item.contributorPEUSENS, Martien-
item.contributorRENAERS, Eleni-
item.contributorPLUSQUIN, Michelle-
item.contributorNAWROT, Tim-
item.fullcitationCROONS, Hanne; MARTENS, Dries; VAN DER STUKKEN, Charlotte; SLEURS, Hanne; RASKING, Leen; PEUSENS, Martien; RENAERS, Eleni; PLUSQUIN, Michelle & NAWROT, Tim (2024) Telomere length in early childhood and its association with attention: a study in 4-6 year old children. In: Frontiers in pediatrics, 12 (Art N° 1358272).-
item.fulltextWith Fulltext-
item.accessRightsOpen Access-
crisitem.journal.issn2296-2360-
crisitem.journal.eissn2296-2360-
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