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http://hdl.handle.net/1942/43641
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DC Field | Value | Language |
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dc.contributor.author | VERGUTS, Jasper | - |
dc.contributor.author | Soors, Eline | - |
dc.contributor.author | CALLEBAUT, Ina | - |
dc.contributor.author | EVERS, Stefan | - |
dc.contributor.author | VANDENBRANDE, Jeroen | - |
dc.contributor.author | Ceulemans, Angelique | - |
dc.contributor.author | SMEETS, Wouter | - |
dc.contributor.author | Al Tmimi, Layth | - |
dc.contributor.author | STESSEL, Bjorn | - |
dc.date.accessioned | 2024-09-02T12:38:11Z | - |
dc.date.available | 2024-09-02T12:38:11Z | - |
dc.date.issued | 2024 | - |
dc.date.submitted | 2024-09-02T11:54:59Z | - |
dc.identifier.citation | BJOG (Oxford. Print), | - |
dc.identifier.uri | http://hdl.handle.net/1942/43641 | - |
dc.description.abstract | Objective: To examine if peritoneal conditioning with an altered insufflation gas mixture is associated with reduced postoperative pain intensity compared to the standard insufflation gas (i.e., 100% CO2). Design: A prospective, single-centre, randomized, double-blind, superiority trial was performed. Setting: This study was conducted between 4 April 2019 and 10 February 2022 at the Jessa Hospital, Hasselt, Belgium. Population: Patients scheduled for elective gynaecologic laparoscopic surgery. Methods: Seventy-four patients scheduled for elective gynaecologic laparoscopic surgery were randomised to receive either the standard insufflation gas with 100 CO2 (n = 37; control group) or the altered gas mixture of 86% CO2, 10% N2O and 4% O-2 (n = 37; experimental group). Main Outcome Measures: Postoperative pain was assessed at 4, 8 and 24 hours after surgery and on postoperative day (POD) 7 by an 11-point Numeric Rating Scale, with 0 indicating no pain and 10 indicating worst imaginable pain. Results: No significant differences were found between the control and experimental groups regarding postoperative pain at 4, 8 and 24 h after surgery, as well as on POD7. In addition, the median (25% and 75%) total amount of IV piritramide consumption during the first 24 h after surgery was not significantly different between groups (control group: 18.0 [10.0, 27.0] mg vs. experimental group: 17.0 [10.0, 34.0] mg, p = 0.62). Conclusion: The alternative insufflation gas mixture comprising 86% CO2, 10% N2O and 4% O-2 used for the pneumoperitoneum during gynaecologic laparoscopic surgery does not appear to reduce postoperative pain compared to the standard insufflation gas of 100% CO2. | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.subject.other | insufflation gas | - |
dc.subject.other | laparoscopic surgery | - |
dc.subject.other | pain | - |
dc.title | Addition of nitrous oxide and oxygen to carbon dioxide pneumoperitoneum during laparoscopic surgery for pain reduction: A double-blinded randomized controlled trial | - |
dc.type | Journal Contribution | - |
local.format.pages | 8 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Verguts, J (corresponding author), Jessa Hosp, Dept Obstet & Gynaecol, Stadsomvaart 11, B-3500 Hasselt, Belgium. | - |
dc.description.notes | jasper.verguts@jessazh.be | - |
local.publisher.place | 111 RIVER ST, HOBOKEN 07030-5774, NJ USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.status | Early view | - |
dc.identifier.doi | 10.1111/1471-0528.17939 | - |
dc.identifier.pmid | 39164861 | - |
dc.identifier.isi | WOS:001294764200001 | - |
dc.contributor.orcid | Callebaut, Ina/0000-0002-6666-6783; Verguts, Jasper/0000-0002-2185-1213 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Verguts, Jasper] Jessa Hosp, Dept Obstet & Gynaecol, Stadsomvaart 11, B-3500 Hasselt, Belgium. | - |
local.description.affiliation | [Verguts, Jasper; Callebaut, Ina; Ceulemans, Angelique; Stessel, Bjorn] LCRC, Fac Med & Life Sci, Diepenbeek, Belgium. | - |
local.description.affiliation | [Soors, Eline; Al Tmimi, Layth] Univ Hosp, Dept Anaesthesiol & Pain Med, Leuven, Belgium. | - |
local.description.affiliation | [Soors, Eline; Callebaut, Ina; Evers, Stefan; Vandenbrande, Jeroen; Stessel, Bjorn] Jessa Hosp, Dept Anesthesiol & Pain Med, Hasselt, Belgium. | - |
local.description.affiliation | [Smeets, Wouter] Univ Hasselt, Data Sci Inst, Diepenbeek, Belgium. | - |
local.description.affiliation | [Al Tmimi, Layth] Katholieke Univ Leuven, Dept Cardiovasc Sci, Leuven, Belgium. | - |
local.uhasselt.international | no | - |
item.fullcitation | VERGUTS, Jasper; Soors, Eline; CALLEBAUT, Ina; EVERS, Stefan; VANDENBRANDE, Jeroen; Ceulemans, Angelique; SMEETS, Wouter; Al Tmimi, Layth & STESSEL, Bjorn (2024) Addition of nitrous oxide and oxygen to carbon dioxide pneumoperitoneum during laparoscopic surgery for pain reduction: A double-blinded randomized controlled trial. In: BJOG (Oxford. Print),. | - |
item.fulltext | No Fulltext | - |
item.contributor | VERGUTS, Jasper | - |
item.contributor | Soors, Eline | - |
item.contributor | CALLEBAUT, Ina | - |
item.contributor | EVERS, Stefan | - |
item.contributor | VANDENBRANDE, Jeroen | - |
item.contributor | Ceulemans, Angelique | - |
item.contributor | SMEETS, Wouter | - |
item.contributor | Al Tmimi, Layth | - |
item.contributor | STESSEL, Bjorn | - |
item.accessRights | Closed Access | - |
crisitem.journal.issn | 1470-0328 | - |
crisitem.journal.eissn | 1471-0528 | - |
Appears in Collections: | Research publications |
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