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http://hdl.handle.net/1942/43649
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DC Field | Value | Language |
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dc.contributor.author | MINGELS, Sarah | - |
dc.contributor.author | GRANITZER, Marita | - |
dc.contributor.author | Schmid, Annina | - |
dc.contributor.author | Graven-Nielsen, Thomas | - |
dc.contributor.author | Dankaerts, Wim | - |
dc.date.accessioned | 2024-09-03T07:56:12Z | - |
dc.date.available | 2024-09-03T07:56:12Z | - |
dc.date.issued | 2024 | - |
dc.date.submitted | 2024-09-03T07:23:14Z | - |
dc.identifier.citation | BMJ open, 14 (6) (Art N° e074743) | - |
dc.identifier.uri | http://hdl.handle.net/1942/43649 | - |
dc.description.abstract | Background An endogenous pain modulation profile, reflecting antinociceptive and pronociceptive mechanisms, may help to direct management by targeting the involved pain mechanism. For individuals with cervicogenic headache (CeH), the characteristics of such profiles were never investigated. However, the individual nature of experiencing pain demands profiling within a multidimensional framework including psychosocial lifestyle characteristics. The objective of the current protocol is to assess the pain modulation profile, which includes psychosocial lifestyle characteristics among people with CeH. Methods and analysis A protocol is described to map pain modulation profiles in people with CeH. A cross-sectional non-randomised experimental design will be used to assess feasibility of mapping these profiles. The pain modulation profile is composed based on results on the Depression, Anxiety, Stress Scale, Pittsburgh Sleep Quality Index, Headache Impact Test and on responses to temporal summation of pain (pinprick), conditioned pain modulation and widespread hyperalgesia (mechanical pressure pain threshold and cuff algometry). Primary analyses will report results relating to outcomes on feasibility. Secondary analyses will involve an analysis of proportions (%) of the different psychosocial lifestyle profiles and pain profiles. Ethics and dissemination Ethical approval was granted by the Ethics Committee Research UZ/KU Leuven (Registration number B3222024001434) on 30 May 2024. Results will be published in peer-reviewed journals, at scientific conferences and, through press releases. Protocol V.3. protocol date: 3 June 2024. | - |
dc.description.sponsorship | AS was funded in whole, or in part, by the Wellcome Trust (222101/Z/20/Z). For the purpose of open access, the author has applied a CC BY public copyright license to any Author Accepted Manuscript version arising from this submission. TGN is a part of the Center for Neuroplasticity and Pain (CNAP) supported by the Danish National Research Foundation (DNRF121). SM is supported by the Leuven University (PDMt1/22/016). The sponsor has no role in composing the study design, collection, management, analysis and interpretation of data, writing of the report or the decision to submit the report for publication. | - |
dc.language.iso | en | - |
dc.publisher | BMJ PUBLISHING GROUP | - |
dc.rights | Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/ licenses/by/4.0/. | - |
dc.subject.other | feasibility studies | - |
dc.subject.other | chronic pain | - |
dc.subject.other | neurological pain | - |
dc.subject.other | risk factors | - |
dc.title | Cross-sectional experimental assessment of pain modulation as part of multidimensional profiling of people with cervicogenic headache: protocol for a feasibility study | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 6 | - |
dc.identifier.volume | 14 | - |
local.format.pages | 10 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Mingels, S (corresponding author), Leuven Univ, Fac Kinesiol & Rehabil Sci, Dept Rehabil Sci, Musculoskeletal Res Unit, Leuven, Belgium.; Mingels, S (corresponding author), Hasselt Univ, Biomed Res Inst, Fac Rehabil Sci, REVAL Rehabil Res Ctr, Hasselt, Belgium. | - |
dc.description.notes | sarah.mingels@kuleuven.be | - |
local.publisher.place | BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | e074743 | - |
dc.identifier.doi | 10.1136/bmjopen-2023-074743 | - |
dc.identifier.pmid | 38890144 | - |
dc.identifier.isi | 001261053900090 | - |
dc.contributor.orcid | Mingels, Sarah/0000-0001-9024-2377 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Mingels, Sarah; Dankaerts, Wim] Leuven Univ, Fac Kinesiol & Rehabil Sci, Dept Rehabil Sci, Musculoskeletal Res Unit, Leuven, Belgium. | - |
local.description.affiliation | [Mingels, Sarah; Granitzer, Marita] Hasselt Univ, Biomed Res Inst, Fac Rehabil Sci, REVAL Rehabil Res Ctr, Hasselt, Belgium. | - |
local.description.affiliation | [Schmid, Annina] Univ Oxford, Nuffield Dept Clin Neurosci, Oxford, England. | - |
local.description.affiliation | [Graven-Nielsen, Thomas] Aalborg Univ, Dept Hlth Sci & Technol, Ctr Neuroplast & Pain CNAP, Aalborg, Denmark. | - |
local.uhasselt.international | yes | - |
item.fullcitation | MINGELS, Sarah; GRANITZER, Marita; Schmid, Annina; Graven-Nielsen, Thomas & Dankaerts, Wim (2024) Cross-sectional experimental assessment of pain modulation as part of multidimensional profiling of people with cervicogenic headache: protocol for a feasibility study. In: BMJ open, 14 (6) (Art N° e074743). | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
item.contributor | MINGELS, Sarah | - |
item.contributor | GRANITZER, Marita | - |
item.contributor | Schmid, Annina | - |
item.contributor | Graven-Nielsen, Thomas | - |
item.contributor | Dankaerts, Wim | - |
crisitem.journal.issn | 2044-6055 | - |
crisitem.journal.eissn | 2044-6055 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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e074743.full.pdf | Published version | 576.09 kB | Adobe PDF | View/Open |
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