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http://hdl.handle.net/1942/43693
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DC Field | Value | Language |
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dc.contributor.author | Yedidya, Idit | - |
dc.contributor.author | STASSEN, Jan | - |
dc.contributor.author | Butcher, Steele | - |
dc.contributor.author | van Wijngaarden, Aniek L. | - |
dc.contributor.author | Wu, Yoska | - |
dc.contributor.author | van der Bijl, Pieter | - |
dc.contributor.author | Marsan, Nina Ajmone | - |
dc.contributor.author | Delgado, Victoria | - |
dc.contributor.author | Bax, Jeroen | - |
dc.date.accessioned | 2024-09-06T14:35:05Z | - |
dc.date.available | 2024-09-06T14:35:05Z | - |
dc.date.issued | 2024 | - |
dc.date.submitted | 2024-09-05T11:30:52Z | - |
dc.identifier.citation | International Journal of Cardiology (print), 414 (Art N° 132414) | - |
dc.identifier.uri | http://hdl.handle.net/1942/43693 | - |
dc.description.abstract | Background: The pulmonary vein (PV) flow pattern is influenced by the presence of mitral regurgitation (MR). After a successful reduction in MR severity, the pattern is expected to be changed. We aimed to evaluate the prognostic value of a change in the PV flow pattern in patients with primary MR undergoing mitral valve repair (MVR). Methods: The PV flow pattern was assessed with transthoracic echocardiography in 216 patients (age 65 [IQR 56-72] years, 70% male) with primary MR before and after surgical MVR. The population was divided according to a change in the PV flow pattern following MVR into 'improvers' and 'non-improvers'. Results: Nonimprovers (15%) had a higher prevalence of paroxysmal AF at baseline (46% vs. 22%, p = 0.004), left ventricular dysfunction (LVEF <= 60%) (39% vs. 21%, p = 0.020), and had lower systolic pulmonary artery pressure (28[IQR 25-38] vs. 35[IQR 26-48] mmHg, p = 0.018) compared to improvers (85%). After a median follow-up of 83[IQR 43-140] months, 26(12%) patients died. Non-improvers had higher mortality rates than improvers (p = 0.009). On multivariable Cox regression analysis, a lack of improvement in the PV flow pattern remained independently associated with all-cause mortality (HR 2.322, 95% CI 1.140 to 4.729, P = 0.020). Conclusion: A lack of improvement in the PV flow pattern is independently associated with worse long-term survival in patients with primary MR undergoing MVR. | - |
dc.description.sponsorship | The Department of Cardiology of the Leiden University Medical Center received research grants from Medtronic, Biotronik, Boston Scientific, GE Healthcare, and Edwards Lifesciences. Idit Yedidya received a fellowship grant from Rabin Medical Center, Israel. Steele C Butcher received funding from European Society of Cardiology (grant number 000080404). | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER IRELAND LTD | - |
dc.rights | 2024 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/bync-nd/4.0/). | - |
dc.subject.other | Pulmonary vein flow changes | - |
dc.subject.other | Prognosis | - |
dc.subject.other | Primary mitral regurgitation. | - |
dc.title | The prognostic value of changes in pulmonary vein flow patterns after surgical repair for primary mitral regurgitation | - |
dc.type | Journal Contribution | - |
dc.identifier.volume | 414 | - |
local.format.pages | 6 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Yedidya, I (corresponding author), Heart Lung Ctr, Dept Cardiol, Albinusdreef 2, NL-2300 RC Leiden, Netherlands. | - |
dc.description.notes | I.Yedidya@lumc.nl | - |
local.publisher.place | ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 132414 | - |
dc.identifier.doi | 10.1016/j.ijcard.2024.132414 | - |
dc.identifier.pmid | 39098612 | - |
dc.identifier.isi | 001291758500001 | - |
dc.contributor.orcid | Delgado, Victoria/0000-0002-9841-2737 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Yedidya, Idit; Stassen, Jan; Butcher, Steele; van Wijngaarden, Aniek L.; Wu, Yoska; van der Bijl, Pieter; Marsan, Nina Ajmone; Delgado, Victoria; Bax, Jeroen] Leiden Univ, Med Ctr, Dept Cardiol, Albinusdreef 2, NL-2300 RC Leiden, Netherlands. | - |
local.description.affiliation | [Yedidya, Idit] Rabin Med Ctr, Dept Cardiol, 39 Jabotinsky St, IL-49100 Petah Tiqwa, Israel. | - |
local.description.affiliation | [Stassen, Jan] Jessa Hosp, Dept Cardiol, Stadsomvaart 11, B-3500 Hasselt, Belgium. | - |
local.description.affiliation | [Butcher, Steele] Royal Perth Hosp, Dept Cardiol, Victoria Sq, Perth, WA 6000, Australia. | - |
local.description.affiliation | [Bax, Jeroen] Univ Turku, Turku PET Ctr, Kiinamyllynkatu 4-8, FI-20520 Turku, Finland. | - |
local.description.affiliation | [Bax, Jeroen] Turku Univ Hosp, Kiinamyllynkatu 4-8, FI-20520 Turku, Finland. | - |
local.description.affiliation | [Yedidya, Idit] Tel Aviv Univ, Fac Med, Tel Aviv, Israel. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.contributor | Yedidya, Idit | - |
item.contributor | STASSEN, Jan | - |
item.contributor | Butcher, Steele | - |
item.contributor | van Wijngaarden, Aniek L. | - |
item.contributor | Wu, Yoska | - |
item.contributor | van der Bijl, Pieter | - |
item.contributor | Marsan, Nina Ajmone | - |
item.contributor | Delgado, Victoria | - |
item.contributor | Bax, Jeroen | - |
item.accessRights | Open Access | - |
item.fullcitation | Yedidya, Idit; STASSEN, Jan; Butcher, Steele; van Wijngaarden, Aniek L.; Wu, Yoska; van der Bijl, Pieter; Marsan, Nina Ajmone; Delgado, Victoria & Bax, Jeroen (2024) The prognostic value of changes in pulmonary vein flow patterns after surgical repair for primary mitral regurgitation. In: International Journal of Cardiology (print), 414 (Art N° 132414). | - |
crisitem.journal.issn | 0167-5273 | - |
crisitem.journal.eissn | 1874-1754 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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The prognostic value of changes in pulmonary vein flow patterns after surgical repair for primary mitral regurgitation.pdf | Published version | 1.06 MB | Adobe PDF | View/Open |
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