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http://hdl.handle.net/1942/44273
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DC Field | Value | Language |
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dc.contributor.author | COLSON, Dries | - |
dc.contributor.author | YALVAC, Burak | - |
dc.contributor.author | Weterings, Jan | - |
dc.contributor.author | Verrijssen, An-Sofie | - |
dc.contributor.author | van Haaren, Paul | - |
dc.contributor.author | Bellezzo, Murillo | - |
dc.contributor.author | Berbee, Maaike | - |
dc.contributor.author | Van Limbergen, Evert J. | - |
dc.contributor.author | Croce, Olivier | - |
dc.contributor.author | Verhaegen, Frank | - |
dc.contributor.author | RENIERS, Brigitte | - |
dc.date.accessioned | 2024-09-20T07:53:41Z | - |
dc.date.available | 2024-09-20T07:53:41Z | - |
dc.date.issued | 2024 | - |
dc.date.submitted | 2024-09-17T11:55:04Z | - |
dc.identifier.citation | Brachytherapy, 23 (5) , p. 535 -548 | - |
dc.identifier.uri | http://hdl.handle.net/1942/44273 | - |
dc.description.abstract | PURPOSE: This study aimed to develop and validate a Monte Carlo (MC) model for the Papillon + contact x-ray brachytherapy (CXB) device, producing 50 kilovolt (kV) X-rays, specifically focusing on its application with a 25 mm diameter rectal applicator for contact therapy. MATERIAL AND METHODS: The validation process involved depth dose and transverse dose profile measurements using EBT3 gafchromic films positioned in a plastic water low energy range phantom. The half-value layer (HVL) was further measured and derived from the simulated X-ray spectra. RESULTS: Excellent agreement within +/- 2% was achieved between the measured and simulated on-axis depth dose curves for the 25 mm rectal applicator. Transverse dose profile measurements showed a high level of agreement between the simulation and measurements, on average 3.1% in contact with the applicator at the surface of the phantom and on average 1.7% at 10 mm depth. A close agreement within 5.5% was noticed concerning the HVL between the measurement and simulation. The simulated gamma spectra and 2D-dose distribution demonstrated a soft X-ray energy spectrum and a uniform dose distribution in contact with the applicator. CONCLUSIONS: An MC model was successfully developed for the Papillon + eBT device with a 25 mm diameter rectal applicator. The validated model, with its demonstrated accuracy in depth dose and transverse dose profile simulations, is a valuable tool for quality assurance and patient safety and, in a later phase, may be used for treatment planning, dose calculations and tissue inhomogeneity corrections. (c) 2024 American Brachytherapy Society. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies. | - |
dc.description.sponsorship | We gratefully acknowledge the financial support provided by the Special Research Fund (Bijzonder Onderzoeksfonds, BOF). This research was made possible through the grant BOF19DOC28 awarded to Dries Colson. We further thank Ariane Medical Systems for providing the data and discussion that made it possible to create the MC model. We also thank prof. Jean-Pierre Gérard for discussion. The PRISM-eBT project with project number 18NRM02 has received funding from the EMPIR programme co-financed by the Participating States and from the European Union’s Horizon 2020 research and innovation programme. The computational resources and services used in this work were provided by the VSC (Flemish Supercomputer Center), funded by the Research Foundation - Flanders (FWO) and the Flemish Government. | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.rights | 2024 American Brachytherapy Society. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies. | - |
dc.subject.other | Monte Carlo modelling | - |
dc.subject.other | Contact X-ray brachytherapy | - |
dc.subject.other | Papillon treatment | - |
dc.subject.other | Rectal cancer | - |
dc.title | Dosimetry and Monte Carlo modelling of the Papillon plus contact X-ray brachytherapy device | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 548 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 535 | - |
dc.identifier.volume | 23 | - |
local.format.pages | 14 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Reniers, B (corresponding author), Hasselt Univ, Nucl Technol Ctr NuTeC, Fac Engn Technol, Martelarenlaan 42, B-3500 Hasselt, Belgium. | - |
dc.description.notes | brigitte.reniers@uhasselt.be | - |
local.publisher.place | STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.brachy.2024.06.003 | - |
dc.identifier.pmid | 38969605 | - |
dc.identifier.isi | 001301531700001 | - |
dc.contributor.orcid | Van Limbergen, Evert/0000-0002-6405-322X; Verrijssen, | - |
dc.contributor.orcid | An-Sofie/0000-0002-5193-2831; verhaegen, frank/0000-0001-8470-386X; van | - |
dc.contributor.orcid | Haaren, Paul/0000-0003-0199-1945; Yalvac, Burak/0000-0003-0262-9980 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Colson, Dries; Yalvac, Burak; Reniers, Brigitte] Hasselt Univ, Nucl Technol Ctr NuTeC, Fac Engn Technol, Martelarenlaan 42, B-3500 Hasselt, Belgium. | - |
local.description.affiliation | [Weterings, Jan; Verrijssen, An-Sofie; van Haaren, Paul] Catharina Hosp, Dept Radiat Oncol, Eindhoven, Netherlands. | - |
local.description.affiliation | [Bellezzo, Murillo; Berbee, Maaike; Van Limbergen, Evert J.; Verhaegen, Frank] Maastricht Univ, GROW Res Inst Oncol & Reprod, Dept Radiat Oncol MAASTRO, Med Ctr, Maastricht, Netherlands. | - |
local.description.affiliation | [Croce, Olivier] Univ Cote dAzur, Inst Res Canc & Aging Nice IRCAN, CNRS, INSERM, Nice, France. | - |
local.uhasselt.international | yes | - |
item.contributor | COLSON, Dries | - |
item.contributor | YALVAC, Burak | - |
item.contributor | Weterings, Jan | - |
item.contributor | Verrijssen, An-Sofie | - |
item.contributor | van Haaren, Paul | - |
item.contributor | Bellezzo, Murillo | - |
item.contributor | Berbee, Maaike | - |
item.contributor | Van Limbergen, Evert J. | - |
item.contributor | Croce, Olivier | - |
item.contributor | Verhaegen, Frank | - |
item.contributor | RENIERS, Brigitte | - |
item.fullcitation | COLSON, Dries; YALVAC, Burak; Weterings, Jan; Verrijssen, An-Sofie; van Haaren, Paul; Bellezzo, Murillo; Berbee, Maaike; Van Limbergen, Evert J.; Croce, Olivier; Verhaegen, Frank & RENIERS, Brigitte (2024) Dosimetry and Monte Carlo modelling of the Papillon plus contact X-ray brachytherapy device. In: Brachytherapy, 23 (5) , p. 535 -548. | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
crisitem.journal.issn | 1538-4721 | - |
crisitem.journal.eissn | 1873-1449 | - |
Appears in Collections: | Research publications |
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ACFrOgDDT7lDYN-J7UgwV2QaRtVid7f3Vr7B98vB80aXUb_DAyrAAMMe6.pdf | Peer-reviewed author version | 1.76 MB | Adobe PDF | View/Open |
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