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http://hdl.handle.net/1942/4499
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DC Field | Value | Language |
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dc.contributor.author | Flameng, W.J. | - |
dc.contributor.author | Herijgers, P. | - |
dc.contributor.author | DEWILDE, Sylvia | - |
dc.contributor.author | LESAFFRE, Emmanuel | - |
dc.date.accessioned | 2007-12-20T15:49:58Z | - |
dc.date.available | 2007-12-20T15:49:58Z | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | The journal of thoracic and cardiovascular surgery, 125(1). p. 121-125 | - |
dc.identifier.issn | 0022-5223 | - |
dc.identifier.uri | http://hdl.handle.net/1942/4499 | - |
dc.description.abstract | Objective: Myocardial preservation studies comparing blood and crystalloid cardioplegia techniques were almost exclusively performed on patients undergoing coronary bypass, and they were unable to show a difference in hospital mortality. We investigated possible factors, including cardioplegia techniques, influencing hospital mortality in patients undergoing cardiac valve surgery. Methods: We evaluated hospital mortality in 1098 consecutive patients undergoing cardiac valve surgery by using a multivariate logistic regression with propensity score balancing of the groups. In 25% of the patients, multiple valve or Bentall procedures were performed, and in 46% of all patients, coronary bypass grafting was associated with valve surgery. A first cohort of 504 consecutive patients were operated on by using single-shot antegrade cold crystalloid cardioplegia, and a second cohort of 594 patients were operated on by using continuous retrograde cold blood cardioplegia. Results: After correction for patient-related and operative risk factors, lower hospital mortality was found in patients who received retrograde blood cardioplegia (P = .020). The odds ratio of in-hospital death when using blood cardioplegia was 0.44 (95% confidence interval, 0.22-0.88). Further predictors of hospital mortality were age, advanced New York Heart Association functional class, cardiopulmonary bypass time, reoperation, active endocarditis, and renal failure. Conclusions: This study shows that continuous retrograde blood cardioplegia is associated with lower hospital mortality in heart valve operations. | - |
dc.language.iso | en | - |
dc.publisher | MOSBY, INC | - |
dc.title | Continuous retrograde blood cardioplegia is associated with lower hospital mortality after heart valve surgery | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 125 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 121 | - |
dc.identifier.volume | 125 | - |
local.bibliographicCitation.jcat | A1 | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.bibliographicCitation.oldjcat | A1 | - |
dc.identifier.doi | 10.1067/mtc.2003.77 | - |
dc.identifier.isi | 000180579300023 | - |
item.fullcitation | Flameng, W.J.; Herijgers, P.; DEWILDE, Sylvia & LESAFFRE, Emmanuel (2003) Continuous retrograde blood cardioplegia is associated with lower hospital mortality after heart valve surgery. In: The journal of thoracic and cardiovascular surgery, 125(1). p. 121-125. | - |
item.accessRights | Closed Access | - |
item.fulltext | No Fulltext | - |
item.contributor | Flameng, W.J. | - |
item.contributor | Herijgers, P. | - |
item.contributor | DEWILDE, Sylvia | - |
item.contributor | LESAFFRE, Emmanuel | - |
crisitem.journal.issn | 0022-5223 | - |
crisitem.journal.eissn | 1097-685X | - |
Appears in Collections: | Research publications |
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