Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/47462
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dc.contributor.authorVAN HOORNWEDER, Sybren-
dc.contributor.authorStagg, Charlotte J.-
dc.contributor.authorWischnewski, Miles-
dc.date.accessioned2025-10-06T08:58:52Z-
dc.date.available2025-10-06T08:58:52Z-
dc.date.issued2025-
dc.date.submitted2025-10-02T11:10:51Z-
dc.identifier.citationTrends in neurosciences, 48 (9) , p. 663 -678-
dc.identifier.urihttp://hdl.handle.net/1942/47462-
dc.description.abstractTranscranial electrical stimulation (tES) encompasses non-invasive neuromodulation techniques, such as transcranial direct and alternating current stimulation, which modulate the central nervous system to probe causal links between the brain and behavior and treat disorders. Unfortunately, fixed stimulation paradigms induce variable effects due to intra-and interindividual factors. Consequently, personalized approaches to tES are increasingly used. In this review, we highlight this emerging domain of human brain stimulation, examining strategies for the personalization of stimulation parameters and their underlying rationales. Multiparameter personalization and the identification of markers indicating tES efficacy represent promising directions. Personalization is not a panacea for all the challenges of tES, but marks an essential step toward reducing the variability of this technique.-
dc.description.sponsorshipWe thank Marten Nuyts and Raf L.J. Meesen for the helpful discussions leading up to this manuscript. S.V.H. is funded by an FWO fellowship fundamental research (G1129923N and G1129925N) and the BOF Incentive fund (BOF22INCENT19). C.J.S. holds a Senior Research Fellowship, funded by the Wellcome Trust (224430/Z/21/Z). M.W. has received a seed grant by the Research School for Behavioral and Cognitive Neurosciences.-
dc.language.isoen-
dc.publisherCELL PRESS-
dc.rights2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. Open access-
dc.subject.otherdosing strategies-
dc.subject.otherindividual variability-
dc.subject.othernon-invasive brain stimulation-
dc.subject.otherprecision neuromodulation-
dc.subject.othertranscranial alternating current stimulation (tACS)-
dc.subject.othertranscranial direct current stimulation (tDCS)-
dc.subject.otherHumans-
dc.subject.otherTranscranial Direct Current Stimulation-
dc.subject.otherBrain-
dc.subject.otherPrecision Medicine-
dc.titlePersonalizing transcranial electrical stimulation-
dc.typeJournal Contribution-
dc.identifier.epage678-
dc.identifier.issue9-
dc.identifier.spage663-
dc.identifier.volume48-
local.format.pages16-
local.bibliographicCitation.jcatA1-
dc.description.notesVan Hoornweder, S (corresponding author), Univ Hasselt, Fac Rehabil Sci, REVAL Rehabil Res Ctr, B-3590 Diepenbeek, Belgium.-
dc.description.notessybren.vanhoornweder@uhasselt.be-
local.publisher.place50 HAMPSHIRE ST, FLOOR 5, CAMBRIDGE, MA 02139 USA-
local.type.refereedRefereed-
local.type.specifiedReview-
dc.identifier.doi10.1016/j.tins.2025.07.007-
dc.identifier.pmid40780974-
dc.identifier.isi001568986300001-
dc.contributor.orcidWischnewski, Miles/0000-0002-0056-6464;-
local.provider.typewosris-
local.description.affiliation[Van Hoornweder, Sybren] Univ Hasselt, Fac Rehabil Sci, REVAL Rehabil Res Ctr, B-3590 Diepenbeek, Belgium.-
local.description.affiliation[Stagg, Charlotte J.] Univ Oxford, John Radcliffe Hosp, Wellcome Ctr Integrat Neuroimaging, Nuffield Dept Clin Neurosci,FMRIB, FMRIB Bldg, Oxford OX3 9DU, England.-
local.description.affiliation[Stagg, Charlotte J.] Univ Oxford, Med Res Council Brain Network Dynam Unit, Nuffield Dept Clin Neurosci, Mansfield Rd, Oxford OX1 3TH, England.-
local.description.affiliation[Wischnewski, Miles] Univ Groningen, Dept Expt Psychol, NL-9712 Groningen, Netherlands.-
local.uhasselt.internationalyes-
item.accessRightsOpen Access-
item.fulltextWith Fulltext-
item.contributorVAN HOORNWEDER, Sybren-
item.contributorStagg, Charlotte J.-
item.contributorWischnewski, Miles-
item.fullcitationVAN HOORNWEDER, Sybren; Stagg, Charlotte J. & Wischnewski, Miles (2025) Personalizing transcranial electrical stimulation. In: Trends in neurosciences, 48 (9) , p. 663 -678.-
crisitem.journal.issn0166-2236-
crisitem.journal.eissn1878-108X-
Appears in Collections:Research publications
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