Importance of basic science and research training for the future generation of cardiologists

Abstract

Advances in the battle against cardiovascular diseases depend upon continuously translating emerging scientific knowledge from preclinical studies and clinical trials into innovative and effective therapeutic strategies. Over the past three decades, molecular and cellular biology have undergone a profound transformation, and large-scale, single-cell, and multi-omics studies have enabled investigations on cardiac disease mechanisms with unprecedented precision. However, these rapid advancements have also contributed to a divergence between the needs and aspirations of basic researchers and those of clinical scientists and practicians, to the detriment of discovery science, precision medicine, and cardiovascular healthcare. The present document highlights the importance of education and training in overcoming the gap between discovery and clinical science, by promoting a common language aimed at designing more translationally relevant and impactful discovery science. To achieve this aim, multidisciplinary efforts will be required to better define learning objectives within training programmes, including education in discovery and clinical sciences, promotion of specific mentorship paths, collaborative research efforts, promotion of equality, diversity, and inclusion, and protection of research time and activity within academic, clinical, and research careers.