Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/48523
Title: Prevention of aortic valve stenosis through modulation of LXRb using saringosterol
Authors: Noethel, M.
Schmidt, A.
Bloemer, H.
Mulder, M. T.
VANMIERLO, Tim 
Friedrichs, S.
Voortman, G.
Goody, P. R.
Zimmer, S.
Nickenig, G.
Luetjohann, D.
Jehle, J.
Issue Date: 2025
Publisher: OXFORD UNIV PRESS
Source: European heart journal, 46 (Supplement_1)
Abstract: Funding Acknowledgements: Type of funding sources: Public grant(s)-National budget only. Main funding source(s): TRR259 BONFOR Background: The liver X receptor-beta (LXRβ) is a regulator of inflammation and cellular cholesterol metabolism. Saringosterol is a ligand of LXR. Both, inflammation and lipid dysregulation promote calcific aortic valve stenosis (AS). Whether saringosterol alleviates AS through LXR signalling is unknown.
Document URI: http://hdl.handle.net/1942/48523
ISSN: 0195-668X
e-ISSN: 1522-9645
DOI: 10.1093/eurheartj/ehaf784.4796
ISI #: 001675719600001
Category: M
Type: Journal Contribution
Appears in Collections:Research publications

Files in This Item:
File Description SizeFormat 
ehaf784.4796.pdfPublished version25.29 kBAdobe PDFView/Open
Show full item record

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.