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http://hdl.handle.net/1942/49340| Title: | Evaluating surrogates for overall survival in the adjuvant treatment of bladder cancer with chemotherapy | Authors: | Sternberg, CN Squifflet, P Saad, ED Burdett, S Fisher, D Kurt, M Teitsson, S May, JR Patel, MY Stoeckle, M Torti, F Cote, R Ruggeri, EM Zhegalik, A Tierney, JF Collette, L BURZYKOWSKI, Tomasz BUYSE, Marc |
Issue Date: | 2025 | Publisher: | ELSEVIER SCIENCE INC | Source: | Urologic oncology, 43 (11) , p. 661e9 -661e17 | Abstract: | Surrogates for overall survival (OS) can expedite the development of adjuvant treatments for bladder cancer. We evaluated whether disease-free survival (DFS) or distant metastasis-free survival (DMFS) are valid surrogates for OS in patients with muscle-invasive disease treated with cisplatin-based chemotherapy after radical cystectomy. | Keywords: | Bladder neoplasms;Platinum compounds;Adjuvant therapy;Surrogate endpoints;Overall survival;Disease-free survival | Document URI: | http://hdl.handle.net/1942/49340 | ISSN: | 1078-1439 | e-ISSN: | 1873-2496 | DOI: | 10.1016/j.urolonc.2025.07.013 | ISI #: | 001588656100006 | Rights: | 2025 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) | Category: | A1 | Type: | Journal Contribution |
| Appears in Collections: | Research publications |
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