A new, fast algorithm to find the regions of possible support for bivariate interval-censored data

Abstract

The estimation of the nonparametric maximum likelihood estimate (NPMLE) of the bivariate distribution function on interval-censored data is a recent topic of research. Among other things, it provides a basic tool for checking a parametric model for the bivariate failure times. As a first step in the estimation of the NPMLE for bivariate interval-censored data, the regions of possible support-that is, the rectangles with nonzero mass-are calculated. For this step a new, fast algorithm is introduced here and compared with two existing algorithms. The advantages of our algorithm will be illustrated on the emergence times of permanent teeth on data from the longitudinal Signal(R) Tandmobiel study.