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http://hdl.handle.net/1942/8243
Title: | Cadmium-induced transcriptional and enzymatic alterations related to oxidative stress | Authors: | SMEETS, Karen RUYTINX, Joske SEMANE, Brahim VAN BELLEGHEM, Frank REMANS, Tony VAN SANDEN, Suzy VANGRONSVELD, Jaco CUYPERS, Ann |
Issue Date: | 2008 | Publisher: | PERGAMON-ELSEVIER SCIENCE LTD | Source: | ENVIRONMENTAL AND EXPERIMENTAL BOTANY, 63(1-3). p. 1-8 | Abstract: | The early antioxidative defence mechanisms were studied in Arabidopsis thaliana by applying a range of realistic Cd concentrations. Our data suggest that a 24 h exposure to 20 mu M CdSO4 is already too toxic to study moderate toxicity, whereas a highly coordinated oxidative stress-related defence response could be observed after Cd application of 5 and 10 mu M. Significant differences in transcript abundance of several genes involved in antioxidative defence were observed. The generation of superoxide seems the main cause of oxidative stress in the roots, whereas in the leaves hydrogen peroxide appears to be an important player. Furthermore, an increased transcript level of lipoxygenase, a potential inducer of oxidative stress, suggests a central role of this gene in causing the Cd-related redox imbalance. Our results show that Cd as a non-redox-active metal induces oxidative stress and indicate that the antioxidative defence system is moderated by the activation of different genes in different organs and cellular compartments. | Notes: | Hasselt Univ, Ctr Environm Sci, B-3590 Diepenbeek, Belgium. Vrije Univ Brussel VIB, B-1050 Brussels, Belgium. Open Univ Netherlands, Sch Sci, NL-6401 DL Heerlen, Netherlands. Hasselt Univ, Ctr Stat, B-3590 Diepenbeek, Belgium.Smeets, K, Hasselt Univ, Ctr Environm Sci, Agoralaan Bldg D, B-3590 Diepenbeek, Belgium.karen.smeets@uhasselt.be | Keywords: | antioxidative defence; Arabidopsis thaliana; cadmium toxicity; environmentally realistic metal concentrations; gene expression; oxidative stress;antioxidative defence; Arabidopsis thaliana; cadmium toxicity; environmentally realistic metal concentrations; gene expression; oxidative stress | Document URI: | http://hdl.handle.net/1942/8243 | ISSN: | 0098-8472 | e-ISSN: | 1873-7307 | DOI: | 10.1016/j.envexpbot.2007.10.028 | ISI #: | 000254671700001 | Rights: | © 2007 Elsevier B.V. All rights reserved. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2009 |
Appears in Collections: | Research publications |
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