Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/9216
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dc.contributor.authorVAN EFFELTERRE, Thierry-
dc.contributor.authorSHKEDY, Ziv-
dc.contributor.authorAERTS, Marc-
dc.contributor.authorMOLENBERGHS, Geert-
dc.contributor.authorVan Damme, P.-
dc.contributor.authorBeutels, P.-
dc.date.accessioned2009-01-29T15:53:28Z-
dc.date.issued2009-
dc.identifier.citationEPIDEMIOLOGY AND INFECTION, 137(1). p. 48-57-
dc.identifier.issn0950-2688-
dc.identifier.urihttp://hdl.handle.net/1942/9216-
dc.description.abstractThe WAIFW matrix (Who Acquires Infection From Whom) is a central parameter in modelling the spread of infectious diseases. The calculation of the basic reproductive number (R-0) depends on the assumptions made about the transmission within and between age groups through the structure of the WAIFW matrix and different structures might lead to different estimates for R-0 and hence different estimates for the minimal immunization coverage needed for the elimination of the infection in the population. In this paper, we estimate R-0 for varicella in Belgium. The force of infection is estimated from seroprevalence data using fractional polynomials and we show how the estimate of R-0 is heavily influenced by the structure of the WAIFW matrix.-
dc.description.sponsorshipThis paper is based on T.v.E.’s M.Sc. thesis in Biostatistics, at Hasselt University. Z.S., M.A., P.V.D. and P.B. acknowledge funding from ‘SIMID’, a strategic basic research project of the Institute for the Promotion of Innovation by Science and Technology in Flanders (IWT), project no. 060081 and POLYMOD, a European Commission project funded within the Sixth Framework Programme, Contract no.: SSP22-CT-2004-502084. Z.S., M.A. and G.M. gratefully acknowledge the financial support from the IAP research network no. P5/24 of the Belgian Government (Belgian Science Policy).-
dc.language.isoen-
dc.publisherCAMBRIDGE UNIV PRESS-
dc.rights© 2008 Cambridge University Press-
dc.titleContact patterns and their implied basic reproductive numbers: an illustration for varicella-zoster virus-
dc.typeJournal Contribution-
dc.identifier.epage57-
dc.identifier.issue1-
dc.identifier.spage48-
dc.identifier.volume137-
local.format.pages10-
local.bibliographicCitation.jcatA1-
dc.description.notes[Van Effelterre, T.; Shkedy, Z.; Aerts, M.; Molenberghs, G.] Hasselt Univ, Ctr Stat Biostat, B-3590 Diepenbeek, Belgium. [Van Damme, P.; Beutels, P.] Univ Antwerp, Ctr Evaluat Vaccinat, B-2020 Antwerp, Belgium. [Beutels, P.] Univ Sydney, Natl Ctr Immunizat Res & Surveillance, Sydney, NSW 2006, Australia.-
local.type.refereedRefereed-
local.type.specifiedArticle-
dc.bibliographicCitation.oldjcatA1-
dc.identifier.doi10.1017/S0950268808000563-
dc.identifier.isi000262067800005-
item.validationecoom 2010-
item.contributorVAN EFFELTERRE, Thierry-
item.contributorSHKEDY, Ziv-
item.contributorAERTS, Marc-
item.contributorMOLENBERGHS, Geert-
item.contributorVan Damme, P.-
item.contributorBeutels, P.-
item.fullcitationVAN EFFELTERRE, Thierry; SHKEDY, Ziv; AERTS, Marc; MOLENBERGHS, Geert; Van Damme, P. & Beutels, P. (2009) Contact patterns and their implied basic reproductive numbers: an illustration for varicella-zoster virus. In: EPIDEMIOLOGY AND INFECTION, 137(1). p. 48-57.-
item.fulltextWith Fulltext-
item.accessRightsRestricted Access-
crisitem.journal.issn0950-2688-
crisitem.journal.eissn1469-4409-
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