HELLINGS, Niels

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HELLINGS, Niels
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niels.hellings@uhasselt.be
 
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Publications

Results 125-186 of 217 (Search time: 0.003 seconds).

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Issue DateTitleContributor(s)TypeCat.
1252012Circulating dendritic cells of multiple sclerosis patients are dysregulated and their frequency is correlated with MS-associated genetic risk factorsHELLINGS, Niels; THEWISSEN, Kristof; Nuyts, A. H.; Deckx, N.; Van Tendeloo, V. F. I.; STINISSEN, Piet; Berneman, Zwi N.; Cools, N.Journal ContributionM
1262012Is there a functional role for KCNMA1 in the multiple sclerosis?VANHEEL, Annelies; BRONE, Bert; DANIELS, Ruth; STINISSEN, Piet; NOBEN, Jean-Paul; HELLINGS, NielsJournal ContributionM
1272012Interleukin-6 class cytokines regulate the development of inflammatory CNS lesionsHELLINGS, Niels; JANSSENS, Kris; HENDRIKS, Jerome; de Vries, H.; Vanwijmeersch, B.; OP 'T EIJNDE, Bert; Van den Haute, C.; Baekelandt, Veerle; STINISSEN, Piet; Slaets, H.Journal ContributionM
1282012Myelin-Derived Lipids Modulate Macrophage Activity by Liver X Receptor ActivationBOGIE, Jeroen; TIMMERMANS, Silke; Huynh-Thu, V.; Irrthum, A.; Smeets, H.J.M.; Gustafsson, J.A.; Steffensen, K.R.; Mulder, M.T.; STINISSEN, Piet; HELLINGS, Niels; HENDRIKS, JeromeJournal ContributionA1
1292012CX(3)CR1 drives cytotoxic CD4(+)CD28(-) T cells into the brain of multiple sclerosis patientsBROUX, Bieke; PANNEMANS, Kim; Zhang, Xin; Markovic-Plese, Silva; BROEKMANS, Tom; OP 'T EIJNDE, Bert; VAN WIJMEERSCH, Bart; SOMERS, Veerle; GEUSENS, Piet; van der Pol, Susanne; VAN HORSSEN, Jack; STINISSEN, Piet; HELLINGS, NielsJournal ContributionA1
1302012B-Cell Depletion Abrogates T Cell-Mediated Demyelination in an Antibody-Nondependent Common Marmoset Experimental Autoimmune Encephalomyelitis ModelJagessar, S.A.; Heijmans, N.; Bauer, J.; Blezer, Erwin L. A.; Laman, Jon D.; HELLINGS, Niels; 't Hart, Bert A.Journal ContributionA1
1312012Pathogenic features of CD4(+)CD28(-) T cells in immune disordersBROUX, Bieke; Markovic-Plese, Silva; STINISSEN, Piet; HELLINGS, NielsJournal ContributionA1
1322012Identification of Protein Networks Involved in the Disease Course of Experimental Autoimmune Encephalomyelitis, an Animal Model of Multiple SclerosisVANHEEL, Annelies; DANIELS, Ruth; Plaisance, Stephane; BAETEN, Kurt; HENDRIKS, Jerome; Leprince, Pierre; DUMONT, Debora; ROBBEN, Johan; BRONE, Bert; STINISSEN, Piet; NOBEN, Jean-Paul; HELLINGS, NielsJournal ContributionA1
1332011Glycine enhances microglial intracellular calcium signaling. A role for sodium-coupled neutral amino acid transportersVAN DEN EYNDEN, Jimmy; NOTELAERS, Kristof; BRONE, Bert; JANSSEN, Daniel; NELISSEN, Katherine; SAHEBALI, Sheen; SMOLDERS, Inge; HELLINGS, Niels; STEELS, Paul; RIGO, Jean-MichelJournal ContributionA1
1342011Preclinical evaluation of mesenchymal-like stem cells derived from umbilical cord matrix as a possible therapeutic tool in multiple sclerosisDONDERS, Raf; MOREELS, Marjan; LAMBRICHTS, Ivo; HENDRIKS, Jerome; HELLINGS, NielsJournal ContributionM
1352011IMMUNOMODULATORY AND THERAPEUTIC PROPERTIES OF LIF IN MULTIPLE SCLEROSISJANSSENS, Kris; SLAETS, Leen; Baekelandt, Veerle; Van den Haute, C.; Vanwijmeersch, B.; OP 'T EIJNDE, Bert; STINISSEN, Piet; HENDRIKS, Jerome; HELLINGS, NielsJournal ContributionM
1362011CX3CR1 DRIVES CD4+CD28NULL CYTOTOXIC T CELLS INTO THE CENTRAL NERVOUS SYSTEM OF MS PATIENTSHELLINGS, Niels; BROUX, Bieke; PANNEMANS, Kim; ZHANG, Xiaoe; Markovic-Plese, Silva; BROEKMANS, Tom; OP 'T EIJNDE, Bert; SOMERS, Veerle; GEUSENS, Piet; STINISSEN, PietJournal ContributionM
1372011NEUROPOIETIC CYTOKINES REGULATE THE DEVELOPMENT OF INFLAMMATORY CNS LESIONSSLAETS, Leen; HENDRIKS, Jerome; de Vries, H.; Van den Haute, C.; Baekelandt, Veerle; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1382011Myelin-phagocytosing macrophages modulate autoreactive T cell proliferationBOGIE, Jeroen; STINISSEN, Piet; HELLINGS, Niels; HENDRIKS, JeromeJournal ContributionA1
1392010Memory CD4(+)CD127(high) T cells from patients with multiple sclerosis produce IL-17 in response to myelin antigensVENKEN, Koen; HELLINGS, Niels; HENSEN, Karen; RUMMENS, Jean-Luc; STINISSEN, PietJournal ContributionA1
1402010Haplotype 4 of the multiple sclerosis-associated interleukin-7 receptor alpha gene influences the frequency of recent thymic emigrants.BROUX, Bieke; HELLINGS, Niels; VENKEN, Koen; RUMMENS, Jean-Luc; HENSEN, Karen; VAN WIJMEERSCH, Bart; STINISSEN, PietJournal ContributionA1
1412010The inhibitory neurotransmitters glycine and GABA ameliorate the disease course of experimental autoimmune encephalomyelitisCARMANS, Sofie; HENDRIKS, Jerome; RIGO, Jean-Michel; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1422010Myelin-phagocytosing macrophages show immunomodulatory propertiesBOGIE, Jeroen; TIMMERMANS, Silke; STINISSEN, Piet; HELLINGS, Niels; HENDRIKS, JeromeJournal ContributionM
1432010Quantitative analysis of brain proteins in an multiple sclerosisDANIELS, Ruth; VANHEEL, Annelies; BAETEN, Kurt; HENDRIKS, Jerome; Stephane, Plaisance; Pierre, Leprince; Debora, Dumont; Johan, Robben; NOBEN, Jean-Paul; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1442010Alterations in phosphorylation status of brain proteins in an animal model of multiple sclerosisVANHEEL, Annelies; DANIELS, Ruth; STINISSEN, Piet; NOBEN, Jean-Paul; HELLINGS, NielsJournal ContributionM
1452010Oncostatin M regulates the development of inflammatory CNS lesionsSLAETS, Leen; HENDRIKS, Jerome; de Vries, Elga; Van den Haute, Chris; Baekelandt, Veerle; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1462010HLA-restricted regulatory CD8 T cells are immunologically altered in multiple sclerosisPANNEMANS, Kim; Goris, An; Dubois, enedicte; BROEKMANS, Tom; VAN WIJMEERSCH, Bart; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1472010CX3CR1 is a marker for senescent CD4+T cells and potentiates migration into the brain of Multiple Sclerosis patientsBROUX, Bieke; HELLINGS, Niels; PANNEMANS, Kim; BROEKMANS, Tom; OP 'T EIJNDE, Bert; VAN WIJMEERSCH, Bart; SOMERS, Veerle; GEUSENS, Piet; STINISSEN, PietJournal ContributionM
1482010Tracking of myelin-reactive T cells in EAE animals using small particles of iron oxide and MRI.BAETEN, Kurt; ADRIAENSENS, Peter; HENDRIKS, Jerome; THEUNISSEN, Evi; LAMBRICHTS, Ivo; GELAN, Jan; HELLINGS, Niels; STINISSEN, PietJournal ContributionA1
1492010The inhibitory neurotransmitter glycine modulates macrophage activity by activation of neutral amino acid transportersCARMANS, Sofie; HENDRIKS, Jerome; THEWISSEN, Kristof; VAN DEN EYNDEN, Jimmy; STINISSEN, Piet; RIGO, Jean-Michel; HELLINGS, NielsJournal ContributionA1
1502010Therapeutic potential of LIF in multiple sclerosisSLAETS, Leen; HENDRIKS, Jerome; STINISSEN, Piet; Kilpatrick, Trevor J.; HELLINGS, NielsJournal ContributionA1
1512010Disturbed regulatory T cell homeostasis in multiple sclerosis.VENKEN, Koen; HELLINGS, Niels; Liblau, Roland; STINISSEN, PietJournal ContributionA1
1522010Involvement of T-cell receptor-beta alterations in the development of otosclerosis linked to OTSC2.Schrauwen, Isabelle; VENKEN, Koen; Vanderstraeten, K; THYS, Melissa; Hendrickx, JJ; Fransen, E; Van Laer, L; Govaerts, PJ; Versteken, M; Schatteman, I; STINISSEN, Piet; HELLINGS, Niels; Van Camp, GJournal ContributionA1
1532010CNS-targeted LIF Expression Improves Therapeutic Efficacy and Limits Autoimmune-mediated Demyelination in a Model of Multiple Sclerosis.SLAETS, Leen; HENDRIKS, Jerome; Van den Haute, Chris; Coun, Freya; Baekelandt, Veerle; STINISSEN, Piet; HELLINGS, NielsJournal ContributionA1
1542010Therapeutic vaccines for autoimmune DiseasesPANNEMANS, Kim; HELLINGS, Niels; STINISSEN, PietJournal ContributionA1
1552009LOCAL LIF PRODUCTION IN THE CNS LIMITS AUTOIMMUNE DEMYELINATIONHENDRIKS, Jerome; SLAETS, Leen; Van den Haute, C.; Baekelandt, Veerle; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1562009ONCOSTATIN M IS A POTENT INDUCER OF CNS INFLAMMATIONSLAETS, Leen; HENDRIKS, Jerome; de Vries, H.; Van den Haute, C.; Baekelandt, Veerle; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1572009Are HLA-E Restricted CD8(+) T Cells Functionally Altered in Multiple Sclerosis?PANNEMANS, Kim; Goris, An; Dobosi, Rita; Dubois, Benedicte; VAN WIJMEERSCH, Bart; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1582009Local LIF Production in the CNS Limits Autoimmune DemyelinationSLAETS, Leen; HENDRIKS, Jerome; Van den Haute, Chris; Baekelandt, Veerle; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1592009A Single Nucleotide Polymorphism within the Interleukin-7 Receptor Alpha Promoter Influences Recent Thymic Emigrants in Multiple SclerosisBROUX, Bieke; HELLINGS, Niels; VENKEN, Koen; VAN WIJMEERSCH, Bart; STINISSEN, PietJournal ContributionM
1602009Oncostatin M is a Potent Inducer of CNS InflammationSLAETS, Leen; HENDRIKS, Jerome; de Vries, Helga; Baekelandt, Veerle; Van den Haute, Chris; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1612009Glycine and glycine receptor signalling in non-neuronal cellsVAN DEN EYNDEN, Jimmy; SAHEBALI, Sheen; HORWOOD, N; CARMANS, Sofie; BRONE, Bert; HELLINGS, Niels; STEELS, Paul; HARVEY, RJ; RIGO, Jean-MichelJournal ContributionA2
1622008T Cell Vaccination with CNS-derived CD4+ T-cells in Multiple Sclerosis: Rationale and immunological responsesHELLINGS, Niels; STINISSEN, PietBook SectionB2
1632008Tovaxin, radiation-attenuated, patient-specific T-cells for the therapeutic vaccination of multiple sclerosisHELLINGS, Niels; STINISSEN, PietJournal ContributionA1
1642008Compromised CD4(+) CD25(high) regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell levelVENKEN, Koen; HELLINGS, Niels; THEWISSEN, Marielle; SOMERS, Veerle; HENSEN, Karen; RUMMENS, Jean-Luc; MEDAER, Rob; Hupperts, Raymond; STINISSEN, PietJournal ContributionA1
1652008Natural naive regulatory T cell development and function are disturbed in multiple sclerosis patientsVENKEN, Koen; HELLINGS, Niels; BROEKMANS, Tom; HENSEN, Karen; RUMMENS, Jean-Luc; STINISSEN, PietJournal ContributionM
1662008Natural naive CD4(+)CD25(+)CD127(low) regulatory T cell (Treg) development and function are disturbed in multiple sclerosis patients: Recovery of memory treg homeostasis during disease progressionVENKEN, Koen; HELLINGS, Niels; BROEKMANS, Tom; HENSEN, Karen; RUMMENS, Jean-Luc; STINISSEN, PietJournal ContributionA1
1672008Natural naive regulatory T cell development and function are disturbed in multiple sclerosis patientsVENKEN, Koen; HELLINGS, Niels; HENSEN, Karen; RUMMENS, Jean-Luc; STINISSEN, PietJournal ContributionM
1682008Activation of myelin reactive T cells in multiple sclerosis: A possible role for T cell degeneracy?STINISSEN, Piet; HELLINGS, NielsJournal ContributionA2
1692008Neuroprotective and immunomodulatory effects of leukemia inhibitory factor during neuroinflammatory responses in multiple sclerosisSLAETS, Leen; HENDRIKS, Jerome; CARMANS, Sofie; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1702008Leukemia inhibitory factor modulates production of inflammatory mediators and myelin phagocytosis by macrophagesHENDRIKS, Jerome; SLAETS, Leen; CARMANS, Sofie; de Vries, Helga; Dijkstra, Christine; STINISSEN, Piet; HELLINGS, NielsJournal ContributionA1
1712008Visualisation of the kinetics of macrophage infiltration during experimental autoimmune encephalomyelitis by magnetic resonance imagingBAETEN, Kurt; HENDRIKS, Jerome; HELLINGS, Niels; THEUNISSEN, Evi; VANDERLOCHT, Joris; DE RYCK, Leen; GELAN, Jan; STINISSEN, Piet; ADRIAENSENS, PeterJournal ContributionA1
1722008Molecular evidence of glycine receptors on macrophages: A possible relationship with multiple sclerosisCARMANS, Sofie; HENDRIKS, Jerome; RIGO, Jean-Michel; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1732008The central nervous system is still susceptible to the infiltration of myelin reactive T cells during the recovery phase of experimental autoimmune encephalomyelitisBAETEN, Kurt; HENDRIKS, Jerome; HELLINGS, Niels; BROUX, Bieke; GELAN, Jan; ADRIAENSENS, Peter; STINISSEN, PietJournal ContributionM
1742008Leukaemia inhibitory factor induces an anti-apoptotic response in oligodendrocytes through Akt-phosphorylation and upregulation of 14-3-3SLAETS, Leen; DUMONT, Debora; VANDERLOCHT, Joris; NOBEN, Jean-Paul; Leprince, P.; ROBBEN, Johan; HENDRIKS, Jerome; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1752008Leukemia inhibitory factor is immunomodulatoryHENDRIKS, Jerome; SLAETS, Leen; CARMANS, Sofie; de Vries, E.; Dijkstra, C.; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1762008Mesenchymal stromal cells derived from bone marrow and Wharton's Jelly as potential sources for cell-based therapies in multiple sclerosisTHEUNISSEN, Evi; MOREELS, Marjan; Ponsaerts, Peter; LAMBRICHTS, Ivo; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1772008Neuroprotective and immunomodulatory effects of leukemia inhibitory factor during neuroinflammatory responses in multiple sclerosisSlaets, Helena; HENDRIKS, Jerome; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1782008Leukemia inhibitory factor induces an antiapoptotic response in oligodendrocytes through Akt-phosphorylation and up-regulation of 14-3-3SLAETS, Leen; DUMONT, Debora; VANDERLOCHT, Joris; NOBEN, Jean-Paul; Leprince, P.; ROBBEN, Johan; HENDRIKS, Jerome; STINISSEN, Piet; HELLINGS, NielsJournal ContributionA1
1792007Leukemia inhibitory factor is immunomodulatory and is secreted by activated macrophages during myelin uptakeHENDRIKS, Jerome; CARMANS, Sofie; SLAETS, Leen; de Vries, Elga; Dijkstra, Christine; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1802007Leukemia inhibitory factor-mediated protection of oligodendrocytes: implications for multiple sclerosisSLAETS, Leen; DUMONT, Debora; VANDERLOCHT, Joris; Leprince, P.; ROBBEN, Johan; HENDRIKS, Jerome; STINISSEN, Piet; HELLINGS, NielsJournal ContributionM
1812007CD4(+)CD28(null) T cells in autoimmune disease: Pathogenic features and decreased susceptibility to immunoregulationTHEWISSEN, Marielle; SOMERS, Veerle; HELLINGS, Niels; FRAUSSEN, Judith; Damoiseaux, Jan; STINISSEN, PietJournal ContributionA1
1822007Characterization of mature rat oligodendrocytes: a proteomic approachDUMONT, Debora; NOBEN, Jean-Paul; MOREELS, Marjan; VANDERLOCHT, Joris; HELLINGS, Niels; VANDENABEELE, Frank; LAMBRICHTS, Ivo; STINISSEN, Piet; ROBBEN, JohanJournal ContributionA1
1832007A CFSE based assay for measuring CD4(+)CD25(+) regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responsesVENKEN, Koen; THEWISSEN, Marielle; HELLINGS, Niels; SOMERS, Veerle; HENSEN, Karen; STINISSEN, Piet; RUMMENS, Jean-LucJournal ContributionA1
1842007The ambivalent nature of T-cell infiltration in the central nervous system of patients with multiple sclerosisVANDERLOCHT, Joris; HELLINGS, Niels; HENDRIKS, Jerome; STINISSEN, PietJournal ContributionA1
1852007Immune mediated protection in multiple sclerosis: A role for neurokines in oligodendrocyte survival and macrophage modulationHELLINGS, Niels; HENDRIKS, Jerome; CARMANS, Sofie; SLAETS, Leen; DUMONT, Debora; VANDERLOCHT, Joris; STINISSEN, PietJournal ContributionM
1862007Reduced number of blood circulating foxp3+CD25highCD4+regulatory T cells and a decreased foxp3 expression at the single-cell level in patients with relapsing-remitting multiple sclerosisVENKEN, Koen; HELLINGS, Niels; SOMERS, Veerle; Meuwissen, Pieter; THEWISSEN, Marielle; HENSEN, Karen; RUMMENS, Jean-Luc; STINISSEN, PietJournal ContributionM
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